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ALEVE NIGHTTIME 220 MG

NAPROXEN SODIUM : 220 MG DIPHENHYDRAMINE HYDROCHLORIDE : 25 MG · DIN 02444593 · BAYER INC

Health Canada status: MARKETED

What is ALEVE NIGHTTIME?

ALEVE NIGHTTIME 220 MG contains NAPROXEN SODIUM : 220 MG DIPHENHYDRAMINE HYDROCHLORIDE : 25 MG. It is listed in the Health Canada Drug Product Database under DIN 02444593, held by BAYER INC, supplied as TABLET for ORAL administration. Health Canada currently lists it as marketed, status dated 24-Feb-2016. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.

What is ALEVE NIGHTTIME used for?

ALEVE® NIGHTTIME (Naproxen Sodium and Diphenhydramine Hydrochloride Tablet) is a non-prescription analgesic and sleep aid preparation to be taken as a single dose of 2 tablets at bedtime. ALEVE® NIGHTTIME is indicated for: • Occasional use, for a limited period of time (five days or less), for fast and effective relief of acute nighttime pain and accompanying sleeplessness caused by aches and pains associated with arthritis, joints, muscles, backache, headache, migraine pain and toothache and, in these circumstances, for increased duration of sleep uninterrupted by pain • Helps you fall asleep and stay asleep

Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.

Product details and regulatory record

DIN02444593
Brand nameALEVE NIGHTTIME
Generic / active ingredientNAPROXEN SODIUM : 220 MG DIPHENHYDRAMINE HYDROCHLORIDE : 25 MG
ManufacturerBAYER INC
Strength220 MG
Dosage formTABLET
Route of administrationORAL
ScheduleNON-PRESCRIPTION DRUGS
ATC codeM01AE02 NAPROXEN
AHFS class28:08.04.92
BiosimilarNo
Health Canada statusMARKETED
Status date24-Feb-2016
Original market date2016-02-24 00:00:00

How is it stored and handled?

null

How is it supplied?

20 and 40 caplets

What can be used instead?

Other Canadian products sharing ATC code M01AE02 NAPROXEN. 31 of 125 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.

ProductStrengthFormManufacturerHealth Canada statusDIN
ALEVE BACK AND BODY PAIN220 MGCAPSULEBAYER INCMARKETEDDIN 02436337
ALEVE CAPLETS220 MGTABLETBAYER INCMARKETEDDIN 02301733
ALEVE LIQUID GELS220 MGCAPSULEBAYER INCMARKETEDDIN 02361795
ANAPROX275 MGTABLETSEARCHLIGHT PHARMA INCMARKETEDDIN 02162725
ANAPROX DS550 MGTABLETSEARCHLIGHT PHARMA INCMARKETEDDIN 02162717
APO-NAPRO-NA275 MGTABLETAPOTEX INCMARKETEDDIN 00784354
APO-NAPRO-NA DS550 MGTABLETAPOTEX INCMARKETEDDIN 01940309
APO-NAPROXEN250 MGTABLETAPOTEX INCMARKETEDDIN 00522651
APO-NAPROXEN375 MGTABLETAPOTEX INCMARKETEDDIN 00600806
APO-NAPROXEN500 MGTABLETAPOTEX INCMARKETEDDIN 00592277

Who else supplies NAPROXEN worldwide?

Nexara tracks national medicine registries and published price lists across multiple markets. NAPROXEN appears in 1493 registered pack listings across 13 markets, published on 10 different national price bases. Where a Canadian route is closed, that is where an alternative route of supply starts — subject to the import rules in both countries.

Registered listings are not stock. Ask us to confirm what can actually be sourced for your order.

How can I get it?

Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.

Request a quote for ALEVE NIGHTTIME

Ordering questions

Who can buy this from Nexara?

Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.

Is there a minimum order?

Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.

What is the lead time?

Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.

Can Nexara supply this for a clinical trial?

Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.

Health Canada Drug Product Database (DPD), DIN 02444593. Last reviewed 2026-09-09. Nexara Health is a licensed wholesaler and supplies licensed entities only; consumer orders are routed to a partner pharmacy.