OCTAPLEX 1240 UNIT
PROTEIN C : 1240 UNIT PROTEIN S : 1280 UNIT COAGULATION FACTOR VII (HUMAN) : 960 UNIT COAGULATION FACTOR IX (HUMAN) : 1000 UNIT COAGULATION FACTOR X (HUMAN) : 1200 UNIT COAGULATION FACTOR II (HUMAN) : 1520 UNIT · DIN 02434970 · OCTAPHARMA PHARMAZEUTIKA PRODUKTIONSGES M B H
Health Canada status: MARKETED
What is OCTAPLEX?
OCTAPLEX 1240 UNIT contains PROTEIN C : 1240 UNIT PROTEIN S : 1280 UNIT COAGULATION FACTOR VII (HUMAN) : 960 UNIT COAGULATION FACTOR IX (HUMAN) : 1000 UNIT COAGULATION FACTOR X (HUMAN) : 1200 UNIT COAGULATION FACTOR II (HUMAN) : 1520 UNIT. It is listed in the Health Canada Drug Product Database under DIN 02434970, held by OCTAPHARMA PHARMAZEUTIKA PRODUKTIONSGES M B H, supplied as POWDER FOR SOLUTION ; KIT for INTRAVENOUS administration. Health Canada currently lists it as marketed, status dated 11-Aug-2015. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is OCTAPLEX used for?
octaplex® (Human Prothrombin Complex) is indicated for: • The treatment of bleeding and perioperative prophylaxis of bleeding in acquired deficiency of the prothrombin complex coagulation factors, such as deficiency caused by treatment with vitamin K antagonists, or in case of overdose of vitamin K antagonists, when rapid correction of the deficiency is required.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
Product details and regulatory record
| DIN | 02434970 |
|---|---|
| Brand name | OCTAPLEX |
| Generic / active ingredient | PROTEIN C : 1240 UNIT PROTEIN S : 1280 UNIT COAGULATION FACTOR VII (HUMAN) : 960 UNIT COAGULATION FACTOR IX (HUMAN) : 1000 UNIT COAGULATION FACTOR X (HUMAN) : 1200 UNIT COAGULATION FACTOR II (HUMAN) : 1520 UNIT |
| Manufacturer | OCTAPHARMA PHARMAZEUTIKA PRODUKTIONSGES M B H |
| Strength | 1240 UNIT |
| Dosage form | POWDER FOR SOLUTION ; KIT |
| Route of administration | INTRAVENOUS |
| Schedule | Schedule D |
| ATC code | B02BD01 COAGULATION FACTOR IX, II, VII AND X IN COMB |
| AHFS class | 20:28.16 |
| Biosimilar | No |
| Health Canada status | MARKETED |
| Status date | 11-Aug-2015 |
| Original market date | 2015-08-11 00:00:00 |
How is it stored and handled?
Do not store above 25 °C. Do not freeze. Store in the original package in order to protect from light. The reconstituted solution can be stored for up to 8 hours at 2°C to 25°C, provided sterility of the stored product is maintained.
How is it supplied?
octaplex® 500 in 20 mL, octaplex® 1000 in 40 mL
What can be used instead?
Other Canadian products sharing ATC code B02BD01 COAGULATION FACTOR IX, II, VII AND X IN COMB. 4 of 4 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.
| Product | Strength | Form | Manufacturer | Health Canada status | DIN |
|---|---|---|---|---|---|
| BERIPLEX P/N 1000 | 1240 UNIT | POWDER FOR SOLUTION | CSL BEHRING CANADA INC | MARKETED | DIN 02410826 |
| BERIPLEX P/N 500 | 680 UNIT | POWDER FOR SOLUTION | CSL BEHRING CANADA INC | MARKETED | DIN 02359251 |
| OCTAPLEX | 480 UNIT | KIT ; POWDER FOR SOLUTION | OCTAPHARMA PHARMAZEUTIKA PRODUKTIONSGES M B H | MARKETED | DIN 02294664 |
Who else supplies COAGULATION FACTOR IX, II, VII AND X IN COMB worldwide?
Nexara tracks national medicine registries and published price lists across multiple markets. COAGULATION FACTOR IX, II, VII AND X IN COMB appears in 109 registered pack listings across 5 markets, published on 3 different national price bases. Where a Canadian route is closed, that is where an alternative route of supply starts — subject to the import rules in both countries.
Registered listings are not stock. Ask us to confirm what can actually be sourced for your order.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.