DUAVIVE 0.45 MG — DIN 02432854
CONJUGATED ESTROGENS 0.45 MG; BAZEDOXIFENE (BAZEDOXIFENE ACETATE) 20 MG · PFIZER CANADA ULC · Tablet (Immediate- And Extended-Release) · wholesale supply in Canada
Health Canada status: MARKETED
What is DUAVIVE?
DUAVIVE 0.45 MG contains CONJUGATED ESTROGENS 0.45 MG; BAZEDOXIFENE (BAZEDOXIFENE ACETATE) 20 MG. It is listed in the Health Canada Drug Product Database under DIN 02432854, held by PFIZER CANADA ULC, supplied as Tablet (Immediate- And Extended-Release) for Oral administration. Health Canada currently lists it as marketed, status dated 09-Jun-2023. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 0.45 MG |
|---|---|
| Dosage form | Tablet (Immediate- And Extended-Release) |
| Route | Oral |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Conjugated Estrogens And Bazedoxifene |
|---|---|
| ATC code | G03CC07 |
| AHFS class | 84:04.92 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02432854 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2432854 |
| Brand name | DUAVIVE |
| Generic / active ingredient | CONJUGATED ESTROGENS 0.45 MG; BAZEDOXIFENE (BAZEDOXIFENE ACETATE) 20 MG |
| Market authorization holder | PFIZER CANADA ULC |
| Health Canada schedule | Prescription |
| ATC code | G03CC07 |
| ATC anatomical main group | G — Genito-urinary system and sex hormones |
| ATC therapeutic subgroup | G03CC |
| Current status | MARKETED |
| Status date | 09-Jun-2023 |
| Original market date | 2016-01-04 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
2 · Same class — other molecules in ATC G03CC
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Conjugated Estrogens And Bazedoxifene | DUAVIVE | 1 | 1 | Yes |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC G03C
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| G03CA | Conjugated Estrogens · Estradiol · Estrone · Ethinylestradiol · Natural And Semisynthetic Estrogens, Plain | 96 | 27 |
| G03CX | Tibolone | 1 | 1 |
| G03CB | Dienestrol · Diethylstilbestrol | 4 | 0 |
4 · Fixed-dose combinations with Canadian supply
| Product | Active ingredients | Holder | Status | DIN |
|---|---|---|---|---|
| DUAVIVE | CONJUGATED ESTROGENS 0.45 MG; BAZEDOXIFENE (BAZEDOXIFENE ACETATE) 20 MG | PFIZER CANADA ULC | MARKETED | 02432854 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is DUAVIVE called?
Also recorded in Canada as: {28 (estrogens, conjugated (USP) 0.625 MG / medroxyprogesterone acetate 2.5 MG Oral Tablet) } Pack (US), {28 (estrogens, conjugated (USP) 0.625 MG / medroxyprogesterone acetate 5 MG Oral Tablet) } Pack (US), {28 (estrogens, conjugated (USP) 0.3 MG / medroxyprogesterone acetate 1.5 MG Oral Tablet) } Pack (US), {28 (estrogens, conjugated (USP) 0.45 MG / medroxyprogesterone acetate 1.5 MG Oral Tablet) } Pack (US), bazedoxifene 20 MG / estrogens, conjugated (USP) 0.45 MG Oral Tablet [Duavee] (US), estrogens, conjugated (USP) 0.625 MG Oral Tablet [Premarin] (US), estrogens, conjugated (USP) 1.25 MG Oral Tablet [Premarin] (US), estrogens, conjugated (USP) 0.3 MG Oral Tablet [Premarin] (US), estrogens, conjugated (USP) 0.9 MG Oral Tablet [Premarin] (US), estrogens, conjugated (USP) 25 MG Injection [Premarin] (US), estrogens, conjugated (USP) 0.45 MG Oral Tablet [Premarin] (US), estrogens, conjugated (USP) 0.625 MG/ML Vaginal Cream [Premarin] (US), estrogens, conjugated (USP) 0.3 MG / medroxyprogesterone acetate 1.5 MG Oral Tablet (US), estrogens, conjugated (USP) 0.45 MG / medroxyprogesterone acetate 1.5 MG Oral Tablet (US), estrogens, conjugated (USP) 0.625 MG / medroxyprogesterone acetate 2.5 MG Oral Tablet (US).
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.