RAMIPRIL-HCTZ 25 MG — DIN 02415909
HYDROCHLOROTHIAZIDE : 25 MG RAMIPRIL : 10 MG · PRO DOC LIMITEE · TABLET · wholesale supply in Canada
Health Canada status: CANCELLED POST MARKET
What is RAMIPRIL-HCTZ?
RAMIPRIL-HCTZ 25 MG contains HYDROCHLOROTHIAZIDE : 25 MG RAMIPRIL : 10 MG. It is listed in the Health Canada Drug Product Database under DIN 02415909, held by PRO DOC LIMITEE, supplied as TABLET for ORAL administration. Health Canada currently lists it as cancelled post market, status dated 10-Apr-2019. This Drug Identification Number is no longer authorized for sale in Canada, so Nexara does not supply it. The record is kept here because buyers still meet the number on old formularies, purchase orders and tender documents; Nexara can help identify an authorized alternative.
How much does Ramipril And Diuretics cost around the world?
Ramipril And Diuretics is listed on 21 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Australia publishes a ex-manufacturer; Austria publishes a KVP (Kassenverkaufspreis); Bahrain publishes a retail (max). Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| Spain | PVP con IVA (public price) | 78 | 81 | EUR███.██ |
| Italy | prezzo al pubblico (classe A) | 30 | 79 | EUR███.██ |
| Australia | ex-manufacturer | 17 | 72 | AUD███.██ |
| Czechia | max producer price (ex-factory) | 11 | 55 | CZK███.██ |
| United States | acquisition | 4 | 52 | USD███.██ |
| Austria | KVP (Kassenverkaufspreis) | 43 | 43 | EUR███.██ |
| South Africa | single exit price | 33 | 35 | ZAR███.██ |
| Sweden | AIP (pharmacy purchase price) | 11 | 34 | SEK███.██ |
| Morocco | PPV (public price) | 6 | 24 | MAD███.██ |
| Romania | max producer price | 21 | 23 | RON███.██ |
| Hungary | producer price (ex-factory) | 19 | 19 | HUF███.██ |
| Norway | max AUP (pharmacy retail) | 2 | 15 | NOK███.██ |
| Saudi Arabia | public | 9 | 12 | SAR███.██ |
| Slovakia | categorised final price | 8 | 10 | EUR███.██ |
| Brazil | preco fabrica (ex-factory ceiling) | 2 | 8 | BRL███.██ |
| Greece | producer price (ex-factory) | 7 | 7 | EUR███.██ |
| Belgium | public | 5 | 5 | EUR███.██ |
| United Kingdom | hospital | 5 | 5 | GBP███.██ |
| United Arab Emirates | public | 3 | 3 | AED███.██ |
| Bahrain | retail (max) | 1 | 3 | BHD███.██ |
| Luxembourg | reimbursement | 3 | 3 | EUR███.██ |
588 pack listings across 318 brand entries and 18 price bases, refreshed 08 Sep 2026. Ranges span every Ramipril And Diuretics pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
Is there a generic Ramipril And Diuretics in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
7 holders have a Canadian DIN containing Ramipril And Diuretics, across 32 DINs, of which 7 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| SUN PHARMA CANADA INC | 5 | 5 | TARO-RAMIPRIL HCTZ | Sourceable in Canada |
| PHARMASCIENCE INC | 5 | 2 | PMS-RAMIPRIL-HCTZ | Sourceable in Canada |
| APOTEX INC | 5 | 0 | APO-RAMIPRIL/HCTZ | No marketed DIN |
| BAUSCH HEALTH, CANADA INC. | 5 | 0 | ALTACE HCT | No marketed DIN |
| TEVA CANADA LIMITED | 5 | 0 | TEVA-RAMIPRIL/HCTZ | No marketed DIN |
| SANIS HEALTH INC | 4 | 0 | RAMIPRIL-HCTZ | No marketed DIN |
| PRO DOC LIMITEE | 3 | 0 | RAMIPRIL-HCTZ | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 25 MG |
|---|---|
| Dosage form | TABLET |
| Route | ORAL |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Ramipril And Diuretics |
|---|---|
| ATC code | C09BA05 |
| AHFS class | 40:28.20 ; 24:32.04 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02415909 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2415909 |
| Brand name | RAMIPRIL-HCTZ |
| Generic / active ingredient | HYDROCHLOROTHIAZIDE : 25 MG RAMIPRIL : 10 MG |
| Market authorization holder | PRO DOC LIMITEE |
| Health Canada schedule | Prescription |
| ATC code | C09BA05 |
| ATC anatomical main group | C — Cardiovascular system |
| ATC therapeutic subgroup | C09BA |
| Current status | CANCELLED POST MARKET |
| Status date | 10-Apr-2019 |
| Original market date | 2013-11-28 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
Is Ramipril And Diuretics in shortage in Canada?
A Canadian shortage report is on file for a product containing this molecule: Active — reported by SANIS HEALTH INC, last seen 19 Aug 2026. A shortage on one presentation does not always affect every DIN of the molecule — the alternatives below list what else is marketed in Canada. Nexara can confirm current availability and identify substitutions or import options where permitted.
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
7 of 32 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| PMS-RAMIPRIL-HCTZ | 10.0 MG | TABLET | PHARMASCIENCE INC | MARKETED | 02342170 |
| PMS-RAMIPRIL-HCTZ | 12.5 MG | TABLET | PHARMASCIENCE INC | MARKETED | 02342154 |
| TARO-RAMIPRIL HCTZ | 12.5 MG | TABLET | SUN PHARMA CANADA INC | MARKETED | 02449439 |
| TARO-RAMIPRIL HCTZ | 5 MG | TABLET | SUN PHARMA CANADA INC | MARKETED | 02449463 |
| TARO-RAMIPRIL HCTZ | 12.5 MG | TABLET | SUN PHARMA CANADA INC | MARKETED | 02449447 |
| TARO-RAMIPRIL HCTZ | 12.5 MG | TABLET | SUN PHARMA CANADA INC | MARKETED | 02449455 |
| TARO-RAMIPRIL HCTZ | 25 MG | TABLET | SUN PHARMA CANADA INC | MARKETED | 02449471 |
| ALTACE HCT | 2.5 MG | TABLET | BAUSCH HEALTH, CANADA INC. | DORMANT | 02283131 |
| ALTACE HCT | 10 MG | TABLET | BAUSCH HEALTH, CANADA INC. | DORMANT | 02283166 |
| ALTACE HCT | 10 MG | TABLET | BAUSCH HEALTH, CANADA INC. | DORMANT | 02283182 |
2 · Same class — other molecules in ATC C09BA
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Perindopril And Diuretics | AG-PERINDOPRIL / INDAPAMIDE · APO-PERINDOPRIL-INDAPAMIDE · ARCOSYL PLUS · ARCOSYL PLUS LD · COVERSYL PLUS · COVERSYL PLUS HD · COVERSYL PLUS LD · JAMP PERINDOPRIL/INDAPAMIDE · MYLAN-PERINDOPRIL/INDAPAMIDE · PERINDOPRIL ERBUMINE/ INDAPAMIDE · PERINDOPRIL ERBUMINE/ INDAPAMIDE HD · PERINDOPRIL ERBUMINE/INDAPAMIDE · PERINDOPRIL ERBUMINE/INDAPAMIDE HD · PERINDOPRIL ERBUMINE/INDAPAMIDE LD · PERINDOPRIL/INDAPAMIDE · PMS-PERINDOPRIL-INDAPAMIDE · SANDOZ PERINDOPRIL ERBUMINE/ INDAPAMIDE · SANDOZ PERINDOPRIL ERBUMINE/ INDAPAMIDE HD · SANDOZ PERINDOPRIL ERBUMINE/ INDAPAMIDE LD · TEVA-PERINDOPRIL/INDAPAMIDE | 36 | 25 | Yes |
| Lisinopril And Diuretics | APO-LISINOPRIL/HCTZ · AVA-LISINOPRIL HCT · LISINOPRIL/HCTZ (TYPE Z) · LISNOPRIL/HCTZ (TYPE P) · MYLAN-LISINOPRIL HCTZ · NTP-LISINOPRIL/HCTZ (TYPE P) · NTP-LISINOPRIL/HCTZ (TYPE Z) · NU-LISINOPRIL/HCTZ · PRINZIDE · SANDOZ LISINOPRIL HCT · TEVA-LISINOPRIL/HCTZ (TYPE P) · TEVA-LISINOPRIL/HCTZ (TYPE Z) · ZESTORETIC | 39 | 12 | Yes |
| Quinapril And Diuretics | ACCURETIC · APO-QUINAPRIL / HCTZ TABLETS · APO-QUINAPRIL/HCTZ · AURO-QUINAPRIL HCTZ · GD-QUINAPRIL HCTZ · JAMP QUINAPRIL / HCTZ · TEVA-QUINAPRIL/HCTZ | 20 | 8 | Yes |
| Ramipril And Diuretics | ALTACE HCT · APO-RAMIPRIL/HCTZ · PMS-RAMIPRIL-HCTZ · RAMIPRIL-HCTZ · TARO-RAMIPRIL HCTZ · TEVA-RAMIPRIL/HCTZ | 32 | 7 | Yes |
| Enalapril And Diuretics | ENALAPRIL MALEATE/HCTZ · ENALAPRIL/HCTZ · TEVA-ENALAPRIL/HCTZ · VASERETIC | 7 | 3 | Yes |
| Cilazapril And Diuretics | APO-CILAZAPRIL/HCTZ · INHIBACE PLUS · TEVA-CILAZAPRIL/HCTZ | 3 | 2 | Yes |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC C09B
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| C09BB | Perindopril And Amlodipine · Ramipril And Felodipine · Trandolapril And Verapamil | 15 | 9 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is RAMIPRIL-HCTZ called?
The same molecule, Ramipril And Diuretics, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| Ramipril Hexal | Latin | Norway, Sweden |
| APO-Ramipril | Latin | Australia |
| Ramipril Sandoz | Latin | Australia |
| EGIRAMLON | Latin | Czechia |
| Triatec | Latin | Morocco, Norway |
| AMPRILAN H | Latin | Czechia |
| Prilace | Latin | Australia |
| RAMIL COMBI | Latin | Czechia |
| Ramipril Viatris | Latin | Australia |
| RAMIPRIL WIN | Latin | Morocco |
| RAMIPRIL-WGR | Latin | Australia |
| TRITACE COMBI | Latin | Czechia |
| Ramipril Krka | Latin | Sweden |
| NAPRIX | Latin | Brazil |
| RALBIOR | Latin | Czechia |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
Can this still be bought in Canada?
No. This Drug Identification Number is cancelled post market in Health Canada's Drug Product Database, so the product is no longer authorized for sale in Canada and Nexara does not supply it. This page is kept as a regulatory record.
If you are looking for a current equivalent, the alternatives above list every product sharing this therapeutic class, with the marketed ones first. Ask us to source an alternative
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.