DOXORUBICIN HYDROCHLORIDE INJECTION 2 MG — DIN 02409275
DOXORUBICIN HYDROCHLORIDE : 2 MG · TEVA CANADA LIMITED · SOLUTION · wholesale supply in Canada
Health Canada status: MARKETED
What is DOXORUBICIN HYDROCHLORIDE INJECTION?
DOXORUBICIN HYDROCHLORIDE INJECTION 2 MG contains DOXORUBICIN HYDROCHLORIDE : 2 MG. It is listed in the Health Canada Drug Product Database under DIN 02409275, held by TEVA CANADA LIMITED, supplied as SOLUTION for INTRAVENOUS ; INTRAVESICAL administration. Health Canada currently lists it as marketed, status dated 27-Feb-2014. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is DOXORUBICIN HYDROCHLORIDE INJECTION used for?
Acute leukemias, Wilms’ tumor, neuroblastomas, soft tissue/bone sarcomas, breast, gynecologic, testicular, bronchogenic, thyroid, bladder, gastric, and head/neck carcinomas; Hodgkin's/non-Hodgkin's.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
How much does Doxorubicin cost around the world?
Doxorubicin is listed on 6 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Australia publishes a ex-manufacturer; Greece publishes a producer price (ex-factory); Hungary publishes a producer price (ex-factory). Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| South Africa | single exit price | 19 | 19 | ZAR███.██ |
| Romania | max producer price | 5 | 11 | RON███.██ |
| Greece | producer price (ex-factory) | 10 | 10 | EUR███.██ |
| Hungary | producer price (ex-factory) | 4 | 9 | HUF███.██ |
| Australia | ex-manufacturer | 2 | 4 | AUD███.██ |
| United Kingdom | hospital | 3 | 3 | GBP███.██ |
56 pack listings across 43 brand entries and 5 price bases, refreshed 08 Sep 2026. Ranges span every Doxorubicin pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
Is there a generic Doxorubicin in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
15 holders have a Canadian DIN containing Doxorubicin, across 25 DINs, of which 7 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| PFIZER CANADA ULC | 8 | 3 | ADRIAMYCIN PFS, ADRIAMYCIN RDF, DOXORUBICIN, DOXORUBICIN HYDROCHLORIDE FOR INJECTION USP | Sourceable in Canada |
| ACCORD HEALTHCARE INC | 1 | 1 | DOXORUBICIN INJECTION, BP | Sourceable in Canada |
| BAXTER CORPORATION | 1 | 1 | CAELYX | Sourceable in Canada |
| TARO PHARMACEUTICALS INC | 1 | 1 | TARO-DOXORUBICIN LIPOSOMAL | Sourceable in Canada |
| TEVA CANADA LIMITED | 1 | 1 | DOXORUBICIN HYDROCHLORIDE INJECTION | Sourceable in Canada |
| DAVID BULL LABORATORIES (PTY) LTD. | 3 | 0 | DOXORUBICIN HCL FOR INJ. U.S.P. 10MG/VIAL, DOXORUBICIN HCL FOR INJ. U.S.P. 150MG/VIAL, DOXORUBICIN HCL FOR INJ. U.S.P. 50MG/VIAL | No marketed DIN |
| CARLO ERBA FARMITALIA SPA | 2 | 0 | ADRIAMYCIN RDF INJ 10MG/VIAL, ADRIAMYCIN RDF INJ 50MG/VIAL | No marketed DIN |
| ADRIA LABORATORIES OF CANADA LTD. | 1 | 0 | ADRIAMYCIN RDF INJ 150MG/VIAL | No marketed DIN |
| DR REDDY'S LABORATORIES LTD | 1 | 0 | PEGYLATED LIPOSOMAL DOXORUBICIN HYDROCHLORIDE FOR INJECTION | No marketed DIN |
| OMEGA LABORATORIES LIMITED | 1 | 0 | DOXORUBICIN HYDROCHLORIDE INJECTION | No marketed DIN |
| PANDA PHARMACEUTICALS INC. | 1 | 0 | DOXORUBICIN HYDROCHLORIDE FOR INJECTION USP | No marketed DIN |
| SOPHERION THERAPEUTICS LLC | 1 | 0 | MYOCET | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 2 MG |
|---|---|
| Dosage form | SOLUTION |
| Route | INTRAVENOUS ; INTRAVESICAL |
| Pack configuration (monograph) | Single-use vials: 10 mg (5 mL), 50 mg (25 mL), and 200 mg (100 mL pharmacy bulk vial). Stoppers not made with natural rubber latex. |
| Storage | Ready to use solution (specific temperature not in provided text, but listed as preservative-free). |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Doxorubicin |
|---|---|
| ATC code | L01DB01 |
| AHFS class | 10:00.00 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02409275 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2409275 |
| Brand name | DOXORUBICIN HYDROCHLORIDE INJECTION |
| Generic / active ingredient | DOXORUBICIN HYDROCHLORIDE : 2 MG |
| Market authorization holder | TEVA CANADA LIMITED |
| Health Canada schedule | Prescription |
| ATC code | L01DB01 |
| ATC anatomical main group | L — Antineoplastic and immunomodulating agents |
| ATC therapeutic subgroup | L01DB |
| Current status | MARKETED |
| Status date | 27-Feb-2014 |
| Original market date | 2014-02-27 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
How is it administered?
IV: 60-75 mg/m2 every 21 days or 20 mg/m2 weekly. Intravesical: 50-80 mg in 50-100 mL saline weekly for 4 weeks. Reduce dose for hepatic dysfunction (bilirubin >1.2 mg/dL).
Included because it drives pack selection and wastage. Consult the monograph.
Contraindications
Hypersensitivity to doxorubicin/anthracyclines; persistent myelosuppression; severe hepatic impairment; severe myocardial insufficiency; recent MI; severe arrhythmias; max cumulative dose reached.
Warnings and precautions
Cardiomyopathy/CHF (max cumulative dose 550 mg/m2); Secondary malignancies (AML/MDS); Severe myelosuppression; Extravasation causes tissue necrosis; Hepatic impairment increases toxicity.
Is Doxorubicin in shortage in Canada?
A Canadian shortage report is on file for a product containing this molecule: Active — reported by TEVA CANADA LIMITED, last seen 09 Sep 2026. A shortage on one presentation does not always affect every DIN of the molecule — the alternatives below list what else is marketed in Canada. Nexara can confirm current availability and identify substitutions or import options where permitted.
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
7 of 25 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| CAELYX | 2 MG | SUSPENSION | BAXTER CORPORATION | MARKETED | 02238389 |
| DOXORUBICIN | 2 MG | SOLUTION | PFIZER CANADA ULC | MARKETED | 02410397 |
| DOXORUBICIN HYDROCHLORIDE FOR INJECTION USP | 150 MG | POWDER FOR SOLUTION | PFIZER CANADA ULC | MARKETED | 02194473 |
| DOXORUBICIN HYDROCHLORIDE FOR INJECTION USP | 50 MG | POWDER FOR SOLUTION | PFIZER CANADA ULC | MARKETED | 02194465 |
| DOXORUBICIN INJECTION, BP | 2 MG | SOLUTION | ACCORD HEALTHCARE INC | MARKETED | 02381982 |
| TARO-DOXORUBICIN LIPOSOMAL | 2 MG | SUSPENSION | TARO PHARMACEUTICALS INC | MARKETED | 02493020 |
| ADRIAMYCIN PFS | 2 MG | SOLUTION | PFIZER CANADA ULC | DORMANT | 02071002 |
| ADRIAMYCIN RDF | 150 MG | POWDER FOR SOLUTION | PFIZER CANADA ULC | CANCELLED POST MARKET | 02069563 |
| ADRIAMYCIN RDF | 50 MG | POWDER FOR SOLUTION | PFIZER CANADA ULC | CANCELLED POST MARKET | 02069555 |
| ADRIAMYCIN RDF | 10 MG | POWDER FOR SOLUTION | PFIZER CANADA ULC | CANCELLED POST MARKET | 02065657 |
2 · Same class — other molecules in ATC L01DB
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Doxorubicin | ADRIAMYCIN PFS · ADRIAMYCIN RDF · ADRIAMYCIN RDF INJ 10MG/VIAL · ADRIAMYCIN RDF INJ 150MG/VIAL · +13 more | 25 | 7 | Yes |
| Daunorubicin | CERUBIDINE · DAUNORUBICIN HYDROCHLORIDE FOR INJECTION · DAUNORUBICIN HYDROCHLORIDE INJECTION · DAUNORUBICIN INJECTABLE SOLUTION · +1 more | 6 | 3 | Yes |
| Epirubicin | EPIRUBICIN FOR INJECTION · EPIRUBICIN HYDROCHLORIDE FOR INJECTION · EPIRUBICIN HYDROCHLORIDE INJECTION · PHARMORUBICIN PFS · +3 more | 15 | 1 | Yes |
| Idarubicin | AJ-IDARUBICIN · IDAMYCIN - CAP 10MG · IDAMYCIN - CAP 25MG · IDAMYCIN - CAP 5MG · +7 more | 12 | 1 | Yes |
| Mitoxantrone | MITOXANTRONE INJECTION · MITOXANTRONE INJECTION USP · NOVANTRONE · NOVANTRONE INJ 2MG/ML | 5 | 1 | Yes |
| Valrubicin | VALTAXIN | 1 | 0 | Not in Canada |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC L01D
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| L01DC | Bleomycin · Mitomycin | 13 | 5 |
| L01DA | Dactinomycin | 1 | 1 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is DOXORUBICIN HYDROCHLORIDE INJECTION called?
The same molecule, Doxorubicin, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| Adriamycin | Latin | Australia |
| Doxorubicin ACC | Latin | Australia |
| Doxorubicin Pch | Latin | South Africa |
| Doxorubicin Rtu | Latin | South Africa |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.