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ENALAPRIL/HCTZ 25 MG

HYDROCHLOROTHIAZIDE : 25 MG ENALAPRIL SODIUM : 8 MG · DIN 02398478 · FROSST A DIVISION OF MERCK CANADA INC

Health Canada status: CANCELLED PRE MARKET

What is ENALAPRIL/HCTZ?

ENALAPRIL/HCTZ 25 MG contains HYDROCHLOROTHIAZIDE : 25 MG ENALAPRIL SODIUM : 8 MG. It is listed in the Health Canada Drug Product Database under DIN 02398478, held by FROSST A DIVISION OF MERCK CANADA INC, supplied as TABLET for ORAL administration. Health Canada currently lists it as cancelled pre market, status dated 05-May-2016. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.

What is ENALAPRIL/HCTZ used for?

Treatment of essential hypertension in patients for whom this combination therapy is appropriate. In using ENALAPRIL/HCTZ consideration should be given to the risk of angioedema. ENALAPRIL/HCTZ is not indicated for initial therapy. Patients in whom enalapril and diuretic are initiated simultaneously can develop symptomatic hypotension. Patients should be titrated on individual drugs. If the fixed combination represents the dose and dosing frequency determined by this titration, the use of ENALAPRIL/HCTZ may be more convenient in the management of patients. If during maintenance therapy dosage adjustment is necessary it is advisable to use the individual drugs.

Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.

Product details and regulatory record

DIN02398478
Brand nameENALAPRIL/HCTZ
Generic / active ingredientHYDROCHLOROTHIAZIDE : 25 MG ENALAPRIL SODIUM : 8 MG
ManufacturerFROSST A DIVISION OF MERCK CANADA INC
Strength25 MG
Dosage formTABLET
Route of administrationORAL
SchedulePrescription
ATC codeC09BA02 ENALAPRIL AND DIURETICS
AHFS class40:28.20 ; 24:32.04
BiosimilarNo
Health Canada statusCANCELLED PRE MARKET
Status date05-May-2016

How is it stored and handled?

null

How is it supplied?

null

What can be used instead?

Other Canadian products sharing ATC code C09BA02 ENALAPRIL AND DIURETICS. 3 of 7 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.

ProductStrengthFormManufacturerHealth Canada statusDIN
ENALAPRIL MALEATE/HCTZ10 MGTABLETAA PHARMA INCMARKETEDDIN 02352931
ENALAPRIL MALEATE/HCTZ12.5 MGTABLETAA PHARMA INCMARKETEDDIN 02352923
VASERETIC8 MGTABLETORGANON CANADA INC.MARKETEDDIN 00657298
TEVA-ENALAPRIL/HCTZ25 MGTABLETTEVA CANADA LIMITEDCANCELLED POST MARKETDIN 02300230
TEVA-ENALAPRIL/HCTZ4 MGTABLETTEVA CANADA LIMITEDCANCELLED POST MARKETDIN 02300222
VASERETIC4 MGTABLETMERCK CANADA INCCANCELLED POST MARKETDIN 02242826

Who else supplies ENALAPRIL AND DIURETICS worldwide?

Nexara tracks national medicine registries and published price lists across multiple markets. ENALAPRIL AND DIURETICS appears in 2538 registered pack listings across 12 markets, published on 9 different national price bases. Where a Canadian route is closed, that is where an alternative route of supply starts — subject to the import rules in both countries.

Registered listings are not stock. Ask us to confirm what can actually be sourced for your order.

Can this still be bought in Canada?

No. This Drug Identification Number is cancelled pre market in Health Canada's Drug Product Database, so the product is no longer authorized for sale in Canada and Nexara does not supply it. This page is kept as a regulatory record.

If you are looking for a current equivalent, the alternatives above list every product sharing this therapeutic class, with the marketed ones first. Ask us to source an alternative

Ordering questions

Who can buy this from Nexara?

Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.

Is there a minimum order?

Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.

What is the lead time?

Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.

Can Nexara supply this for a clinical trial?

Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.

Health Canada Drug Product Database (DPD), DIN 02398478. Last reviewed 2026-09-09. Nexara Health is a licensed wholesaler and supplies licensed entities only; consumer orders are routed to a partner pharmacy.