TEVA-ATOVAQUONE PROGUANIL 100 MG — DIN 02380927
PROGUANIL HYDROCHLORIDE : 100 MG ATOVAQUONE : 250 MG · TEVA CANADA LIMITED · TABLET · wholesale supply in Canada
Health Canada status: MARKETED
What is TEVA-ATOVAQUONE PROGUANIL?
TEVA-ATOVAQUONE PROGUANIL 100 MG contains PROGUANIL HYDROCHLORIDE : 100 MG ATOVAQUONE : 250 MG. It is listed in the Health Canada Drug Product Database under DIN 02380927, held by TEVA CANADA LIMITED, supplied as TABLET for ORAL administration. Health Canada currently lists it as marketed, status dated 01-Mar-2012. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is TEVA-ATOVAQUONE PROGUANIL used for?
Prophylaxis of P. falciparum malaria (including chloroquine-resistant areas). Treatment of acute, uncomplicated P. falciparum malaria.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
Is there a generic Proguanil And Atovaquone in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
5 holders have a Canadian DIN containing Proguanil And Atovaquone, across 6 DINs, of which 6 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| GLAXOSMITHKLINE INC | 2 | 2 | MALARONE, MALARONE PEDIATRIC | Sourceable in Canada |
| GLENMARK PHARMACEUTICALS CANADA INC. | 1 | 1 | ATOVAQUONE AND PROGUANIL HYDROCHLORIDE TABLETS | Sourceable in Canada |
| MYLAN PHARMACEUTICALS ULC | 1 | 1 | MYLAN-ATOVAQUONE/PROGUANIL | Sourceable in Canada |
| SANIS HEALTH INC | 1 | 1 | ATOVAQUONE PROGUANIL | Sourceable in Canada |
| TEVA CANADA LIMITED | 1 | 1 | TEVA-ATOVAQUONE PROGUANIL | Sourceable in Canada |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 100 MG |
|---|---|
| Dosage form | TABLET |
| Route | ORAL |
| Pack configuration (monograph) | Not explicitly detailed in provided text (standard tablets). |
| Storage | Not explicitly detailed in provided text. |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Proguanil And Atovaquone |
|---|---|
| ATC code | P01BB51 |
| AHFS class | 08:30.08 ; 08:30.92 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02380927 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2380927 |
| Brand name | TEVA-ATOVAQUONE PROGUANIL |
| Generic / active ingredient | PROGUANIL HYDROCHLORIDE : 100 MG ATOVAQUONE : 250 MG |
| Market authorization holder | TEVA CANADA LIMITED |
| Health Canada schedule | Prescription |
| ATC code | P01BB51 |
| ATC anatomical main group | P — Antiparasitic products, insecticides and repellents |
| ATC therapeutic subgroup | P01BB |
| Current status | MARKETED |
| Status date | 01-Mar-2012 |
| Original market date | 2012-03-01 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
How is it administered?
Take with food or a milky drink. Repeat dose if vomiting occurs within 1 hour. Not recommended for treatment/prophylaxis in children weighing less than 40 kg.
Included because it drives pack selection and wastage. Consult the monograph.
Contraindications
Hypersensitivity to atovaquone, proguanil hydrochloride, or any component. Prophylaxis in patients with severe renal impairment (CrCl < 30 mL/min).
Warnings and precautions
Serious hypersensitivity (anaphylaxis) possible. Not for cerebral or complicated malaria. Monitor parasitemia if diarrhea/vomiting occurs or with certain drug interactions.
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
6 of 6 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| ATOVAQUONE AND PROGUANIL HYDROCHLORIDE TABLETS | 250 MG | TABLET | GLENMARK PHARMACEUTICALS CANADA INC. | MARKETED | 02466783 |
| ATOVAQUONE PROGUANIL | 100 MG | TABLET | SANIS HEALTH INC | MARKETED | 02421429 |
| MALARONE | 100 MG | TABLET | GLAXOSMITHKLINE INC | MARKETED | 02238151 |
| MALARONE PEDIATRIC | 62.5 MG | TABLET | GLAXOSMITHKLINE INC | MARKETED | 02264935 |
| MYLAN-ATOVAQUONE/PROGUANIL | 100 MG | TABLET | MYLAN PHARMACEUTICALS ULC | MARKETED | 02402165 |
2 · Same class — other molecules in ATC P01BB
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Proguanil And Atovaquone | ATOVAQUONE AND PROGUANIL HYDROCHLORIDE TABLETS · ATOVAQUONE PROGUANIL · MALARONE · MALARONE PEDIATRIC · +2 more | 6 | 6 | Yes |
| Proguanil | PALUDRINE TAB 0.1GM · PALUDRINE TAB 100MG | 2 | 0 | Not in Canada |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC P01B
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| P01BA | Chloroquine · Hydroxychloroquine · Primaquine | 15 | 7 |
| P01BC | Mefloquine · Quinine | 21 | 5 |
| P01B | Antimalarials | 1 | 0 |
| P01BD | Pyrimethamine · Pyrimethamine, Combinations | 2 | 0 |
| P01BX | Halofantrine | 1 | 0 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is TEVA-ATOVAQUONE PROGUANIL called?
The same molecule, Proguanil And Atovaquone, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| Malarone | Latin | Slovakia |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.