TISSEEL 125 MG
SEALER PROTEIN (HUMAN) : 125 MG THROMBIN (HUMAN) : 500 UNIT APROTININ (SYNTHETIC) : 3000 KIU CALCIUM CHLORIDE : 40 MCMOL · DIN 02326132 · BAXTER CORPORATION
Health Canada status: MARKETED
What is TISSEEL?
TISSEEL 125 MG contains SEALER PROTEIN (HUMAN) : 125 MG THROMBIN (HUMAN) : 500 UNIT APROTININ (SYNTHETIC) : 3000 KIU CALCIUM CHLORIDE : 40 MCMOL. It is listed in the Health Canada Drug Product Database under DIN 02326132, held by BAXTER CORPORATION, supplied as KIT for TOPICAL administration. Health Canada currently lists it as marketed, status dated 15-Feb-2016. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is TISSEEL used for?
TISSEEL (Fibrin Sealant (Human), Vapor Heated, Solvent Detergent Treated) is indicated for: addition to standard measures, to achieve hemostasis, to seal or glue tissue, and to support wound healing. It is also indicated for use in abdominal surgery, cardiovascular surgery, orthopedic surgery, thoracic surgery, and urology.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
Product details and regulatory record
| DIN | 02326132 |
|---|---|
| Brand name | TISSEEL |
| Generic / active ingredient | SEALER PROTEIN (HUMAN) : 125 MG THROMBIN (HUMAN) : 500 UNIT APROTININ (SYNTHETIC) : 3000 KIU CALCIUM CHLORIDE : 40 MCMOL |
| Manufacturer | BAXTER CORPORATION |
| Strength | 125 MG |
| Dosage form | KIT |
| Route of administration | TOPICAL |
| Schedule | Schedule D |
| ATC code | B02BC30 COMBINATIONS |
| Biosimilar | No |
| Health Canada status | MARKETED |
| Status date | 15-Feb-2016 |
How is it stored and handled?
Unopened pouches of TISSEEL 500 IU (Fast Set), thawed at room temperature, may be stored for up to 7 days at room temperature (15°C - 25°C) after removal from the freezer. Prior to use, the product should be warmed to 33°C to 37°C. After thawing, the product must not be refrigerated, refrozen or be exposed to temperatures above 37°C. Keep the product at 33°C - 37°C until needed. The product must be used within 12 hours after warming to 33°C - 37°C or removal from original pouches.
How is it supplied?
2 mL, 4 mL, 10 mL
What can be used instead?
Other Canadian products sharing ATC code B02BC30 COMBINATIONS. 5 of 12 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.
| Product | Strength | Form | Manufacturer | Health Canada status | DIN |
|---|---|---|---|---|---|
| ARTISS | 3000 KIU | SOLUTION | BAXTER CORPORATION | MARKETED | DIN 02326167 |
| TISSEEL | 125 MG | SOLUTION | BAXTER CORPORATION | MARKETED | DIN 02326175 |
| VISTASEAL | 400 MG / 5 ML | SOLUTION | INSTITUTO GRIFOLS S.A. | MARKETED | DIN 02514257 |
| VISTASEAL | 80 MG / 1 ML | SOLUTION | INSTITUTO GRIFOLS S.A. | MARKETED | DIN 02514222 |
| EVICEL | 90 MG | SOLUTION ; KIT | OMRIX BIOPHARMACEUTICALS LTD | CANCELLED POST MARKET | DIN 02348497 |
| QUIXIL | 60.0 MG | KIT ; SOLUTION | OMRIX BIOPHARMACEUTICALS LTD | APPROVED | DIN 02283980 |
| TACHOSIL | 2 UNIT | PATCH | CORZA MEDICAL GMBH | APPROVED | DIN 02439026 |
| TACHOSIL | 2 UNIT | PATCH | CORZA MEDICAL GMBH | APPROVED | DIN 02439034 |
| TACHOSIL | 5.5 MG | PATCH | CORZA MEDICAL GMBH | DORMANT | DIN 02439042 |
| TISSEEL KIT VH 0.5 | 55 MG | KIT ; POWDER FOR SOLUTION ; LIQUID | BAXTER AG | CANCELLED POST MARKET | DIN 02233272 |
Who else supplies COMBINATIONS worldwide?
Nexara tracks national medicine registries and published price lists across multiple markets. COMBINATIONS appears in 5 registered pack listings across 2 markets, published on 2 different national price bases. Where a Canadian route is closed, that is where an alternative route of supply starts — subject to the import rules in both countries.
Registered listings are not stock. Ask us to confirm what can actually be sourced for your order.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.