APO-LEVOFLOXACIN 750 MG — DIN 02325942
LEVOFLOXACIN (LEVOFLOXACIN HEMIHYDRATE) : 750 MG · APOTEX INC · TABLET · wholesale supply in Canada
Health Canada status: MARKETED
What is APO-LEVOFLOXACIN?
APO-LEVOFLOXACIN 750 MG contains LEVOFLOXACIN (LEVOFLOXACIN HEMIHYDRATE) : 750 MG. It is listed in the Health Canada Drug Product Database under DIN 02325942, held by APOTEX INC, supplied as TABLET for ORAL administration. Health Canada currently lists it as marketed, status dated 24-Jun-2009. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is APO-LEVOFLOXACIN used for?
Treatment of adults with bacterial infections: sinusitis, bronchitis exacerbations, pneumonia (community-acquired and nosocomial), skin infections, UTI, pyelonephritis, and chronic prostatitis.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
How much does Levofloxacin cost around the world?
Levofloxacin is listed on 14 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Austria publishes a KVP (Kassenverkaufspreis); Bahrain publishes a retail (max); Czechia publishes a max producer price (ex-factory). Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| Saudi Arabia | public | 50 | 59 | SAR███.██ |
| South Africa | single exit price | 40 | 53 | ZAR███.██ |
| United States | acquisition | 4 | 27 | USD███.██ |
| Greece | producer price (ex-factory) | 25 | 25 | EUR███.██ |
| Bahrain | retail (max) | 15 | 21 | BHD███.██ |
| Romania | max producer price | 18 | 21 | RON███.██ |
| Hungary | producer price (ex-factory) | 10 | 16 | HUF███.██ |
| Austria | KVP (Kassenverkaufspreis) | 11 | 12 | EUR███.██ |
| Czechia | max producer price (ex-factory) | 7 | 11 | CZK███.██ |
| Luxembourg | reimbursement | 11 | 11 | EUR███.██ |
| Sweden | AIP (pharmacy purchase price) | 6 | 10 | SEK███.██ |
| United Arab Emirates | public | 2 | 7 | AED███.██ |
| United Kingdom | hospital | 5 | 5 | GBP███.██ |
| Iceland | max wholesale | 2 | 2 | ISK███.██ |
280 pack listings across 206 brand entries and 12 price bases, refreshed 05 Sep 2026. Ranges span every Levofloxacin pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
Is there a generic Levofloxacin in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
19 holders have a Canadian DIN containing Levofloxacin, across 54 DINs, of which 16 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| TEVA CANADA LIMITED | 10 | 3 | ACT LEVOFLOXACIN, LEVOFLOXACIN INJECTION, NTP-LEVOFLOXACIN, TEVA-LEVOFLOXACIN | Sourceable in Canada |
| APOTEX INC | 3 | 3 | APO-LEVOFLOXACIN | Sourceable in Canada |
| JAMP PHARMA CORPORATION | 3 | 3 | JAMP LEVOFLOXACIN | Sourceable in Canada |
| SANDOZ CANADA INCORPORATED | 3 | 3 | SANDOZ LEVOFLOXACIN | Sourceable in Canada |
| HIKMA CANADA LIMITED | 1 | 1 | LEVOFLOXACIN IN 5% DEXTROSE INJECTION | Sourceable in Canada |
| HORIZON THERAPEUTICS IRELAND DAC | 1 | 1 | QUINSAIR | Sourceable in Canada |
| PFIZER CANADA ULC | 1 | 1 | LEVOFLOXACIN IN 5% DEXTROSE INJECTION | Sourceable in Canada |
| PRO DOC LIMITEE | 1 | 1 | LEVOFLOXACIN | Sourceable in Canada |
| JANSSEN INC | 5 | 0 | LEVAQUIN, LEVAQUIN 25MG/ML, LEVAQUIN 500MG, LEVAQUIN 5MG/ML, LEVAQUIN 750MG | No marketed DIN |
| DOMINION PHARMACAL | 3 | 0 | DOM-LEVOFLOXACIN | No marketed DIN |
| LABORATOIRE RIVA INC. | 3 | 0 | RIVA-LEVOFLOXACIN | No marketed DIN |
| MINT PHARMACEUTICALS INC | 3 | 0 | MINT-LEVOFLOXACIN | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 750 MG |
|---|---|
| Dosage form | TABLET |
| Route | ORAL |
| Pack configuration (monograph) | 250 mg and 500 mg: Bottles of 50 and 100 tablets. 750 mg: Bottles of 30 and 100 tablets. |
| Storage | Not explicitly stated in the provided text (refer to section 11 of full monograph). Typically 15-30°C for such tablets. |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Levofloxacin |
|---|---|
| ATC code | J01MA12 |
| AHFS class | 08:12.18 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02325942 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2325942 |
| Brand name | APO-LEVOFLOXACIN |
| Generic / active ingredient | LEVOFLOXACIN (LEVOFLOXACIN HEMIHYDRATE) : 750 MG |
| Market authorization holder | APOTEX INC |
| Health Canada schedule | Prescription |
| ATC code | J01MA12 |
| ATC anatomical main group | J — Anti-infectives for systemic use |
| ATC therapeutic subgroup | J01MA |
| Current status | MARKETED |
| Status date | 24-Jun-2009 |
| Original market date | 2009-06-24 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
How is it administered?
Adults: 250 mg, 500 mg, or 750 mg orally every 24 hours depending on infection type. Adjust dose for renal impairment (ClCr < 80 mL/min). Take 2 hours before/after antacids or metal cations.
Included because it drives pack selection and wastage. Consult the monograph.
Contraindications
Hypersensitivity to levofloxacin or quinolones; history of tendinitis or tendon rupture associated with quinolone use.
Warnings and precautions
Disabling/persistent reactions (tendonitis, neuropathy, neuropsychiatric); QT prolongation; serious hypersensitivity; seizures; exacerbation of myasthenia gravis; aortic aneurysm/dissection risk.
Is Levofloxacin in shortage in Canada?
A Canadian shortage report is on file for a product containing this molecule: Anticipated — reported by PFIZER CANADA ULC, last seen 09 Sep 2026. A shortage on one presentation does not always affect every DIN of the molecule — the alternatives below list what else is marketed in Canada. Nexara can confirm current availability and identify substitutions or import options where permitted.
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
16 of 54 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| ACT LEVOFLOXACIN | 500 MG | TABLET | TEVA CANADA LIMITED | MARKETED | 02315432 |
| ACT LEVOFLOXACIN | 250 MG | TABLET | TEVA CANADA LIMITED | MARKETED | 02315424 |
| ACT LEVOFLOXACIN | 750 MG | TABLET | TEVA CANADA LIMITED | MARKETED | 02315440 |
| APO-LEVOFLOXACIN | 500 MG | TABLET | APOTEX INC | MARKETED | 02284715 |
| APO-LEVOFLOXACIN | 250 MG | TABLET | APOTEX INC | MARKETED | 02284707 |
| JAMP LEVOFLOXACIN | 250 MG | TABLET | JAMP PHARMA CORPORATION | MARKETED | 02508443 |
| JAMP LEVOFLOXACIN | 750 MG | TABLET | JAMP PHARMA CORPORATION | MARKETED | 02508478 |
| JAMP LEVOFLOXACIN | 500 MG | TABLET | JAMP PHARMA CORPORATION | MARKETED | 02508451 |
| LEVOFLOXACIN | 500 MG | TABLET | PRO DOC LIMITEE | MARKETED | 02415879 |
| LEVOFLOXACIN IN 5% DEXTROSE INJECTION | 5 MG | SOLUTION | PFIZER CANADA ULC | MARKETED | 02314932 |
2 · Same class — other molecules in ATC J01MA
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Ciprofloxacin | ACT CIPROFLOXACIN · AG-CIPROFLOXACIN · APO-CIPROFLOX · AURO-CIPROFLOXACIN · +50 more | 139 | 29 | Yes |
| Levofloxacin | ACT LEVOFLOXACIN · APO-LEVOFLOXACIN · AURO-LEVOFLOXACIN · AVA-LEVOFLOXACIN · +19 more | 54 | 16 | Yes |
| Moxifloxacin | AG-MOXIFLOXACIN · APO-MOXIFLOXACIN · APO-MOXIFLOXACIN HYDROCHLORIDE · AURO-MOXIFLOXACIN · +20 more | 25 | 8 | Yes |
| Delafloxacin | BAXDELA | 2 | 2 | Yes |
| Norfloxacin | AVA-NORFLOXACIN · CO NORFLOXACIN · NORFLOXACIN · NORFLOXACINE-400 · +5 more | 12 | 1 | Yes |
| Ofloxacin | FLOXIN I.V. LIQ 20MG/ML · FLOXIN TABLETS 200MG · FLOXIN TABLETS 300MG · FLOXIN TABLETS 400MG · +2 more | 10 | 0 | Not in Canada |
| Gatifloxacin | NOVO-GATIFLOXACIN · TEQUIN · TEQUIN IV | 5 | 0 | Not in Canada |
| Trovafloxacin | TROVAN I.V. · TROVAN TABLETS 100MG · TROVAN TABLETS 200MG | 3 | 0 | Not in Canada |
| Grepafloxacin | RAXAR | 1 | 0 | Not in Canada |
| Gemifloxacin | FACTIVE | 1 | 0 | Not in Canada |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC J01M
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| J01MB | Nalidixic Acid | 1 | 0 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is APO-LEVOFLOXACIN called?
The same molecule, Levofloxacin, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| LEVOACT | Latin | Saudi Arabia |
| Levofloxacin Krka | Latin | Sweden |
| Levofloxacin Viatris | Latin | Czechia, Sweden |
| Oftaquix | Latin | Saudi Arabia, Sweden |
| RAFLOX | Latin | Saudi Arabia |
| TAVANIC | Latin | Bahrain |
| Eradocin | Latin | Saudi Arabia |
| LEVANIX | Latin | Bahrain |
| LEVOFLOX | Latin | Bahrain |
| Levofloxacin Orion | Latin | Sweden |
| Levonic | Latin | Bahrain, Saudi Arabia |
| MATADOR | Latin | Bahrain |
| MAXITROL | Latin | Czechia |
| Nevotic | Latin | Saudi Arabia |
| SPERSADEX COMP. | Latin | Czechia |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.