ORIGINAL ANTIBIOTIC CREAM 0.25 MG — DIN 02317656
GRAMICIDIN : 0.25 MG POLYMYXIN B SULFATE : 10000 UNIT · TARO PHARMACEUTICALS INC · CREAM · wholesale supply in Canada
Health Canada status: MARKETED
What is ORIGINAL ANTIBIOTIC CREAM?
ORIGINAL ANTIBIOTIC CREAM 0.25 MG contains GRAMICIDIN : 0.25 MG POLYMYXIN B SULFATE : 10000 UNIT. It is listed in the Health Canada Drug Product Database under DIN 02317656, held by TARO PHARMACEUTICALS INC, supplied as CREAM for TOPICAL administration. Health Canada currently lists it as marketed, status dated 26-Oct-2010. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
How much does Combinations Of Antibiotics cost around the world?
Combinations Of Antibiotics is listed on 4 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Czechia publishes a max producer price (ex-factory); Hungary publishes a producer price (ex-factory); Iceland publishes a max wholesale. Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| Hungary | producer price (ex-factory) | 5 | 5 | HUF███.██ |
| Czechia | max producer price (ex-factory) | 1 | 1 | CZK███.██ |
| Iceland | max wholesale | 1 | 1 | ISK███.██ |
| Luxembourg | reimbursement | 1 | 1 | EUR███.██ |
8 pack listings across 8 brand entries and 4 price bases, refreshed 05 Sep 2026. Ranges span every Combinations Of Antibiotics pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
Is there a generic Combinations Of Antibiotics in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
20 holders have a Canadian DIN containing Combinations Of Antibiotics, across 48 DINs, of which 16 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| TARO PHARMACEUTICALS INC | 7 | 7 | ANTIBIOTIC CREAM FOR KIDS, ANTIBIOTIC OINTMENT USP, ANTIBIOTIC PLUS PAIN RELIEF CREAM, COMPLETE ANTIBIOTIC OINTMENT, ORIGINAL ANTIBIOTIC CREAM, +2 more | Sourceable in Canada |
| KENVUE CANADA INC. | 6 | 6 | POLYSPORIN ANTIBIOTIC CREAM, POLYSPORIN ANTIBIOTIC OINTMENT, POLYSPORIN COMPLETE, POLYSPORIN FOR KIDS, POLYSPORIN PLUS PAIN RELIEF, +1 more | Sourceable in Canada |
| JOHNSON & JOHNSON INC | 6 | 1 | BAND-AID BRAND ADHESIVE BANDAGES PLUS ANTIBIOTIC, BAND-AID-S-1, FIRST AID ANTIBIOTIC, FIRST AID ANTIBIOTIC OINTMENT, POLYSPORIN FOR STITCHES, +1 more | Sourceable in Canada |
| EXZELL PHARMA INC | 1 | 1 | OZONOL ANTIBIOTICS PLUS | Sourceable in Canada |
| ODAN LABORATORIES LTD | 1 | 1 | BIODERM OINTMENT | Sourceable in Canada |
| CELLCHEM PHARMACEUTICALS INC. | 5 | 0 | ANTIBIOTIC CREAM, ANTIBIOTIC CREAM FOR KIDS, ANTIBIOTIC CREAM PLUS PAIN RELIEF, ANTIBIOTIC OINTMENT, TRIPLE ANTIBIOTIC OINTMENT | No marketed DIN |
| CANADIAN CUSTOM PACKAGING COMPANY | 3 | 0 | ANTIBIOTIC CREAM, ANTIBIOTIC CREAM PLUS PAIN RELIEF, ANTIBIOTIC CREAM PLUS PAIN RELIEF FOR KIDS | No marketed DIN |
| GLAXO WELLCOME INC. | 3 | 0 | LIDOSPORIN CREAM, POLYSPORIN BURN FORMULA CREAM, POLYSPORIN CREAM | No marketed DIN |
| JAMP PHARMA CORPORATION | 3 | 0 | ANTIBIOTIC OINTMENT, JAMPOLYCIN, TRIPLE ANTIBIOTIC OINTMENT | No marketed DIN |
| CRLS | 2 | 0 | ORIGINAL ANTIBIOTIC CREAM, TOPICAL ANTIBIOTIC OINTMENT | No marketed DIN |
| WARNER-LAMBERT CANADA INC. | 2 | 0 | LIDOSPORIN CREAM, POLYSPORIN ANTIBIOTIC BURN CREAM | No marketed DIN |
| ROUSSEL CANADA INC. | 1 | 0 | SOFRAMYCIN OINTMENT | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 0.25 MG |
|---|---|
| Dosage form | CREAM |
| Route | TOPICAL |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Combinations Of Antibiotics |
|---|---|
| ATC code | D06AX30 |
| AHFS class | 84:04.04 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02317656 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2317656 |
| Brand name | ORIGINAL ANTIBIOTIC CREAM |
| Generic / active ingredient | GRAMICIDIN : 0.25 MG POLYMYXIN B SULFATE : 10000 UNIT |
| Market authorization holder | TARO PHARMACEUTICALS INC |
| Health Canada schedule | NON-PRESCRIPTION DRUGS |
| ATC code | D06AX30 |
| ATC anatomical main group | D — Dermatologicals |
| ATC therapeutic subgroup | D06AX |
| Current status | MARKETED |
| Status date | 26-Oct-2010 |
| Original market date | 2010-10-26 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
16 of 48 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| ANTIBIOTIC CREAM FOR KIDS | 0.25 MG | CREAM | TARO PHARMACEUTICALS INC | MARKETED | 02315033 |
| ANTIBIOTIC OINTMENT USP | 10000 UNIT | OINTMENT | TARO PHARMACEUTICALS INC | MARKETED | 02230251 |
| ANTIBIOTIC PLUS PAIN RELIEF CREAM | 0.25 MG | CREAM | TARO PHARMACEUTICALS INC | MARKETED | 02304457 |
| BAND-AID BRAND ADHESIVE BANDAGES PLUS ANTIBIOTIC | 10000 UNIT | OINTMENT ; PAD | JOHNSON & JOHNSON INC | MARKETED | 02236954 |
| BIODERM OINTMENT | 10000 UNIT | OINTMENT | ODAN LABORATORIES LTD | MARKETED | 00621366 |
| COMPLETE ANTIBIOTIC OINTMENT | 0.25 MG | OINTMENT | TARO PHARMACEUTICALS INC | MARKETED | 02304465 |
| OZONOL ANTIBIOTICS PLUS | 40 MG | OINTMENT | EXZELL PHARMA INC | MARKETED | 02236917 |
| POLYDERM OINTMENT USP | 500 UNIT | OINTMENT | TARO PHARMACEUTICALS INC | MARKETED | 02181908 |
| POLYSPORIN ANTIBIOTIC CREAM | 10000 UNIT | CREAM | KENVUE CANADA INC. | MARKETED | 02230844 |
| POLYSPORIN ANTIBIOTIC OINTMENT | 500 UNIT | OINTMENT | KENVUE CANADA INC. | MARKETED | 02237227 |
2 · Same class — other molecules in ATC D06AX
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Combinations Of Antibiotics | ANTIBIOTIC COLD SORE OINTMENT · ANTIBIOTIC CREAM · ANTIBIOTIC CREAM FOR KIDS · ANTIBIOTIC CREAM PLUS PAIN RELIEF · +34 more | 48 | 16 | Yes |
| Fusidic Acid | FUCIDIN CREAM 2% · FUCIDIN OINTMENT 2% · TARO-FUSIDIC ACID | 3 | 3 | Yes |
| Bacitracin | ANTIBIOTIC OINTMENT · ANTIBIOTIQUE ONGUENT · BACIGUENT FIRST AID OINTMENT · BACIGUENT FIRST AID OINTMENT 500UNITS/GM · +22 more | 33 | 2 | Yes |
| Mupirocin | BACTROBAN · BACTROBAN CREAM · BACTROBAN NASAL OINTMENT · STRAMUCIN · +1 more | 5 | 2 | Yes |
| Bacitracin, Combinations | ANTIBIOTIC OINTMENT · EXTRA STRENGTH BACITRAYCIN PLUS · OZONOL ANTIBIOTIC PLUS - OINTMENT · OZONOL ANTIBIOTIC PLUS ONT · +3 more | 7 | 0 | Not in Canada |
| Gentamicin | GARAMYCIN CREAM 0.1% · GARAMYCIN ONT 0.1% · PMS-GENTAMICIN CREAM 1MG/GM · PMS-GENTAMICIN OINTMENT 1MG/GM · +1 more | 6 | 0 | Not in Canada |
| Neomycin | AMINODERM POUDRE · CICATRIN POWDER · MYCIGUENT OINTMENT · NEOSPORIN ANTIBIOTIC CREAM · +2 more | 6 | 0 | Not in Canada |
| Ozenoxacin | OZANEX | 1 | 0 | Not in Canada |
| Retapamulin | ALTARGO | 1 | 0 | Not in Canada |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC D06A
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| D06AA | Chlortetracycline · Tetracycline | 3 | 0 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is ORIGINAL ANTIBIOTIC CREAM called?
The same molecule, Combinations Of Antibiotics, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| Ekyflogyl | Latin | Iceland |
| OTIPAX | Latin | Czechia |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.