STERILE WATER FOR INJECTION USP 100 % — DIN 02299186
WATER : 100 % · HIKMA CANADA LIMITED · SOLUTION · wholesale supply in Canada
Health Canada status: MARKETED
What is STERILE WATER FOR INJECTION USP?
STERILE WATER FOR INJECTION USP 100 % contains WATER : 100 %. It is listed in the Health Canada Drug Product Database under DIN 02299186, held by HIKMA CANADA LIMITED, supplied as SOLUTION for INTRAVENOUS ; SUBCUTANEOUS ; INTRAMUSCULAR administration. Health Canada currently lists it as marketed, status dated 08-Jan-2024. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is STERILE WATER FOR INJECTION USP used for?
Sterile Water for Injection USP is indicated for use in adults and pediatric patients as a diluent or solvent in the aseptic preparation of parenteral solutions or as a vehicle for drug administration.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
Is there a generic Solvents And Diluting Agents, Incl Irrigat Solut in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
36 holders have a Canadian DIN containing Solvents And Diluting Agents, Incl Irrigat Solut, across 62 DINs, of which 23 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| PFIZER CANADA ULC | 4 | 4 | BACTERIOSTATIC SODIUM CHLORIDE INJECTION USP, BACTERIOSTATIC WATER FOR INJECTION USP, BACTERIOSTATIC WATER FOR INJECTION USP-PRE-FILLED SYRINGE, STERILE WATER FOR INJECTION USP | Sourceable in Canada |
| ALK-ABELLO INC | 3 | 3 | GLYCERINATED PHENOL SALINE, PHENOL SALINE INJ, STERILE DILUENT FOR ALLERGENIC EXTRACT - ALBUMIN SALINE WITH PHENOL | Sourceable in Canada |
| OMEGA LABORATORIES LIMITED | 6 | 2 | ALBUMIN HUMAN DILUENT, BACTERIOSTATIC WATER FOR INJECTION USP, DILUENT STERILE, SODIUM CHLORIDE BACTERIOSTATIC INJ, STERILE WATER FOR INJECTION USP | Sourceable in Canada |
| ALCON CANADA INC | 4 | 2 | BSS PLUS, BSS STERILE IRRIGATING SOLUTION, EYE STREAM, NAVSTEL | Sourceable in Canada |
| B. BRAUN MEDICAL INC | 3 | 2 | STERILE WATER FOR INJECTION USP, STERILE WATER FOR IRRIGATION USP | Sourceable in Canada |
| BAXTER CORPORATION | 3 | 2 | STERILE WATER FOR INJECTION, USP, STERILE WATER FOR IRRIGATION, USP, SYNOVISOL IRRIGATION SOLUTION 2.6% | Sourceable in Canada |
| HIKMA CANADA LIMITED | 2 | 2 | 0.9% SODIUM CHLORIDE INJECTION USP, STERILE WATER FOR INJECTION USP | Sourceable in Canada |
| ICU MEDICAL CANADA INC | 3 | 1 | STERILE WATER FOR INJECTION USP, STERILE WATER FOR IRRIGATION USP | Sourceable in Canada |
| MERCK CANADA INC | 3 | 1 | STERILE DILUENT FOR MERCK SHARP & DOHME LLC LIVE, ATTENUATED, VIRUS VACCINES, STERILE WATER FOR INJECTION USP | Sourceable in Canada |
| GLAXOSMITHKLINE INC | 2 | 1 | PH 12 STERILE DILUENT FOR FLOLAN, STERILE DILUENT FOR FLOLAN INJECTION | Sourceable in Canada |
| B. BRAUN MELSUNGEN AG | 1 | 1 | STERILE WATER FOR INJECTION USP | Sourceable in Canada |
| BAXTER HEALTHCARE CORPORATION | 1 | 1 | STERILE WATER FOR INJECTION USP | Sourceable in Canada |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 100 % |
|---|---|
| Dosage form | SOLUTION |
| Route | INTRAVENOUS ; SUBCUTANEOUS ; INTRAMUSCULAR |
| Pack configuration (monograph) | Sterile Water for Injection USP is supplied sterile and nonpyrogenic in single use 10 mL LDPE plastic ampoules and in single use 10 mL type I glass vials. The ampoules are available in boxes of 20 and the vials are available in boxes of 10. |
| Storage | Exposure of pharmaceutical products to heat should be minimized. Avoid excessive heat. Protect from freezing. It is recommended that the product be stored at 15 – 30°C. |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation, because this listing covers more than one of them.
Substance and classification
| Active substance | Solvents And Diluting Agents, Incl Irrigat Solut |
|---|---|
| ATC code | V07AB |
| AHFS class | 40:20.00 ; 40:12.00 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02299186 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2299186 |
| Brand name | STERILE WATER FOR INJECTION USP |
| Generic / active ingredient | WATER : 100 % |
| Market authorization holder | HIKMA CANADA LIMITED |
| Health Canada schedule | Ethical |
| ATC code | V07AB |
| ATC anatomical main group | V — Various |
| ATC therapeutic subgroup | V07AB |
| Current status | MARKETED |
| Status date | 08-Jan-2024 |
| Original market date | 2008-04-07 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
How is it administered?
This solution is for intramuscular, intravenous or subcutaneous use. Do not inject until made isotonic by addition of appropriate solute. The dosage and administration of Sterile Water for Injection USP is dependent upon the recommended dosage and administration of the solute used. Some additives may be incompatible. Consult with pharmacist or call the manufacturer at 1-800-656-0793 for any questions or concerns. When introducing additives, use aseptic techniques. Mix thoroughly. Do not store. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration.
Included because it drives pack selection and wastage. Consult the monograph.
Contraindications
Sterile Water for Injection USP is a hemolytic agent due to its hypotonicity. Therefore, it is contraindicated for intramuscular, intravenous, or subcutaneous administration without admixing with solute.
Warnings and precautions
Hypotonic and hemolytic. Do not inject until made isotonic by addition of an appropriate solute, due to the possibility of hemolysis. The administration of intravenous solutions can cause fluid and/or solute overload resulting in dilution of serum electrolyte concentrations, overhydration, congested states or pulmonary edema. The risk of dilutional states is inversely proportional to the electrolyte concentration.
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
23 of 62 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| 0.9% SODIUM CHLORIDE INJECTION USP | 9 MG | SOLUTION | HIKMA CANADA LIMITED | MARKETED | 02304341 |
| BACTERIOSTATIC SODIUM CHLORIDE INJECTION USP | 9 MG | SOLUTION | PFIZER CANADA ULC | MARKETED | 00037818 |
| BACTERIOSTATIC WATER FOR INJECTION USP | 30 ML / 30 ML | SOLUTION | PFIZER CANADA ULC | MARKETED | 00038202 |
| BACTERIOSTATIC WATER FOR INJECTION USP-PRE-FILLED SYRINGE | 99.1 % | LIQUID | PFIZER CANADA ULC | MARKETED | 02215721 |
| BSS PLUS | 0.042 % | SOLUTION ; KIT | ALCON CANADA INC | MARKETED | 00568082 |
| BSS STERILE IRRIGATING SOLUTION | 0.17 % | SOLUTION | ALCON CANADA INC | MARKETED | 00512990 |
| GLYCERINATED PHENOL SALINE | 0.4 % | LIQUID | ALK-ABELLO INC | MARKETED | 00298417 |
| PH 12 STERILE DILUENT FOR FLOLAN | 94 MG | LIQUID | GLAXOSMITHKLINE INC | MARKETED | 02443651 |
| PHENOL SALINE INJ | 0.9 % | LIQUID | ALK-ABELLO INC | MARKETED | 00298409 |
| SODIUM CHLORIDE BACTERIOSTATIC INJ | 9 MG | LIQUID | OMEGA LABORATORIES LIMITED | MARKETED | 00402249 |
2 · Same class — other molecules in ATC V07AB
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Solvents And Diluting Agents, Incl Irrigat Solut | 0.9% SODIUM CHLORIDE INJECTION USP · ALBUMIN HUMAN DILUENT · BACTERIOSTATIC SOD CHLOR DILUENT FOR INH · BACTERIOSTATIC SODIUM CHLORIDE DILUENT FOR INHALATION · +37 more | 62 | 23 | Yes |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC V07A
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| V07AC | Blood Transfusion, Auxiliary Products | 25 | 12 |
| V07AV | Technical Disinfectants | 6 | 1 |
| V07AD | Blood Tests, Auxiliary Products | 2 | 0 |
| V07AT | Cosmetics | 1 | 0 |
| V07AX | Washing Agents Etc. | 3 | 0 |
| V07AY | Other Non-Therapeutic Auxiliary Products | 6 | 0 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is STERILE WATER FOR INJECTION USP called?
Also recorded in Canada as: water 984 MG/ML Ophthalmic Irrigation Solution [Dorama-Neo] (US), water 983 MG/ML Ophthalmic Irrigation Solution [Pur-Wash] (US), water 985 MG/ML Ophthalmic Irrigation Solution [Opticlear] (US), water 988 MG/ML Ophthalmic Irrigation Solution [OcuFresh] (US), water 986 MG/ML Ophthalmic Irrigation Solution [Eye Stream] (US), water 980 MG/ML Ophthalmic Irrigation Solution (US), water 951 MG/ML Ophthalmic Irrigation Solution (US), water 986 MG/ML Ophthalmic Irrigation Solution (US), water 991 MG/ML Ophthalmic Irrigation Solution (US), water 983 MG/ML Ophthalmic Irrigation Solution (US), water 984 MG/ML Ophthalmic Irrigation Solution (US), water 985 MG/ML Ophthalmic Irrigation Solution (US), water 988 MG/ML Ophthalmic Irrigation Solution (US), water 1000 MG/ML Irrigation Solution (US), water 1000 MG/ML Ophthalmic Irrigation Solution (US).
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.