LINESSA 21 0.025 MG — DIN 02272903
ETHINYL ESTRADIOL : 0.025 MG DESOGESTREL : 0.15 MG DESOGESTREL : 0.125 MG ETHINYL ESTRADIOL : 0.025 MG DESOGESTREL : 0.1 MG ETHINYL ESTRADIOL : 0.025 MG · ASPEN PHARMACARE CANADA INC. · TABLET · wholesale supply in Canada
Health Canada status: MARKETED
What is LINESSA 21?
LINESSA 21 0.025 MG contains ETHINYL ESTRADIOL : 0.025 MG DESOGESTREL : 0.15 MG DESOGESTREL : 0.125 MG ETHINYL ESTRADIOL : 0.025 MG DESOGESTREL : 0.1 MG ETHINYL ESTRADIOL : 0.025 MG. It is listed in the Health Canada Drug Product Database under DIN 02272903, held by ASPEN PHARMACARE CANADA INC., supplied as TABLET for ORAL administration. Health Canada currently lists it as marketed, status dated 15-Feb-2019. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is LINESSA 21 used for?
Prevention of pregnancy (Oral Contraceptive).
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
How much does Desogestrel And Estrogen cost around the world?
Desogestrel And Estrogen is listed on 12 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Bahrain publishes a retail (max); Brazil publishes a preco fabrica (ex-factory ceiling); Greece publishes a producer price (ex-factory). Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| Brazil | preco fabrica (ex-factory ceiling) | 12 | 46 | BRL███.██ |
| Spain | PVP con IVA (public price) | 16 | 16 | EUR███.██ |
| Saudi Arabia | public | 8 | 11 | SAR███.██ |
| Sweden | AIP (pharmacy purchase price) | 6 | 11 | SEK███.██ |
| Norway | max AUP (pharmacy retail) | 5 | 5 | NOK███.██ |
| South Africa | single exit price | 4 | 4 | ZAR███.██ |
| Bahrain | retail (max) | 3 | 3 | BHD███.██ |
| United Arab Emirates | public | 2 | 2 | AED███.██ |
| United Kingdom | hospital | 1 | 1 | GBP███.██ |
| Greece | producer price (ex-factory) | 1 | 1 | EUR███.██ |
| Morocco | PPV (public price) | 1 | 1 | MAD███.██ |
| Romania | max producer price | 1 | 1 | RON███.██ |
102 pack listings across 60 brand entries and 11 price bases, refreshed 07 Sep 2026. Ranges span every Desogestrel And Estrogen pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
Is there a generic Desogestrel And Estrogen in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
Only one market authorization holder has a Canadian DIN containing Desogestrel And Estrogen — 2 DINs, of which 2 are currently marketed. There is no second Canadian source today, so a supply interruption on this holder has no domestic substitute at the same molecule.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| ASPEN PHARMACARE CANADA INC. | 2 | 2 | LINESSA 21, LINESSA 28 | Sourceable in Canada |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 0.025 MG |
|---|---|
| Dosage form | TABLET |
| Route | ORAL |
| Pack configuration (monograph) | Blister card dispenser in a sealed aluminum laminated sachet. LINESSA 21 contains 21 tablets; LINESSA 28 contains 28 tablets (21 active, 7 inactive). |
| Storage | Not explicitly stated in the provided text (Section 11 is in the Table of Contents but text ends at Section 7). |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Desogestrel And Estrogen |
|---|---|
| ATC code | G03AB05 |
| AHFS class | 68:12.00 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02272903 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2272903 |
| Brand name | LINESSA 21 |
| Generic / active ingredient | ETHINYL ESTRADIOL : 0.025 MG DESOGESTREL : 0.15 MG DESOGESTREL : 0.125 MG ETHINYL ESTRADIOL : 0.025 MG DESOGESTREL : 0.1 MG ETHINYL ESTRADIOL : 0.025 MG |
| Market authorization holder | ASPEN PHARMACARE CANADA INC. |
| Health Canada schedule | Prescription |
| ATC code | G03AB05 |
| ATC anatomical main group | G — Genito-urinary system and sex hormones |
| ATC therapeutic subgroup | G03AB |
| Current status | MARKETED |
| Status date | 15-Feb-2019 |
| Original market date | 2006-06-13 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
How is it administered?
One tablet daily at the same time for 21 or 28 days. 21-day: 21 active tablets then 7 days off. 28-day: 21 active tablets then 7 green inactive tablets. Start Day 1 or first Sunday of cycle.
Included because it drives pack selection and wastage. Consult the monograph.
Contraindications
Hypersensitivity; history of venous/arterial thrombosis, stroke, or liver tumours; severe hepatic disease; sex steroid-influenced malignancies; undiagnosed vaginal bleeding; pregnancy; smoking >35y.
Warnings and precautions
Cigarette smoking increases risk of serious cardiovascular effect (especially >35 years). Increased risk of VTE, MI, and stroke. Does not protect against HIV/AIDS or STIs.
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
2 of 2 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| LINESSA 28 | 0.025 MG | TABLET | ASPEN PHARMACARE CANADA INC. | MARKETED | 02257238 |
2 · Same class — other molecules in ATC G03AB
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Norgestimate And Ethinylestradiol | TRI-CIRA 21 · TRI-CIRA 28 · TRI-CIRA LO 21 · TRI-CIRA LO 28 · +2 more | 6 | 6 | Yes |
| Norethisterone And Estrogen | LOLO · ORTHO 10/11 TABLETS (21 DAY) · ORTHO 10/11 TABLETS (28 DAY) · ORTHO 7/7/7 TABLETS (21 DAY) · +4 more | 9 | 3 | Yes |
| Levonorgestrel And Estrogen | QUATERNA · SEASONIQUE · TRIPHASIL 21 · TRIPHASIL 21 TAB · +4 more | 8 | 3 | Yes |
| Desogestrel And Estrogen | LINESSA 21 · LINESSA 28 | 2 | 2 | Yes |
| Norgestimate And Estrogen | CENTRISA 21 · CENTRISA 28 · CENTRISA LO 21 · CENTRISA LO 28 · +8 more | 12 | 0 | Not in Canada |
| Progestogens And Estrogens, Sequential Preparations | TRI-PREVIFEM (21 DAY) · TRI-PREVIFEM (28 DAY) | 2 | 0 | Not in Canada |
| Dienogest And Estrogen | NATAZIA | 1 | 0 | Not in Canada |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC G03A
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| G03AA | Desogestrel And Estrogen · Drospirenone And Estetrol · Drospirenone And Estrogen · Etynodiol And Estrogen · Levonorgestrel And Estrogen · +4 more | 105 | 46 |
| G03AC | Drospirenone · Etonogestrel · Levonorgestrel · Medroxyprogesterone · Norethisterone · +1 more | 13 | 6 |
| G03AD | Levonorgestrel · Ulipristal | 14 | 5 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is LINESSA 21 called?
The same molecule, Desogestrel And Estrogen, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| DESOGESTREL | Latin | Brazil |
| Cerazette | Latin | Bahrain, Brazil, Morocco, Norway |
| CARELI | Latin | Brazil |
| KELLY | Latin | Brazil |
| MAYSA | Latin | Brazil |
| Vinelle | Latin | Norway, Sweden |
| Azalia | Latin | Sweden |
| Desogestrel Sandoz | Latin | Sweden |
| Gestrina | Latin | Sweden |
| GRACIAL TABLET | Latin | Saudi Arabia |
| Marvelon | Latin | Bahrain, South Africa |
| MARVELON TAB | Latin | Saudi Arabia |
| MELIK | Latin | Brazil |
| NACTALI | Latin | Brazil |
| ONUA | Latin | Brazil |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.