APO-METHIMAZOLE 5 MG
METHIMAZOLE : 5 MG · DIN 02258935 · APOTEX INC
Health Canada status: DORMANT
What is APO-METHIMAZOLE?
APO-METHIMAZOLE 5 MG contains METHIMAZOLE : 5 MG. It is listed in the Health Canada Drug Product Database under DIN 02258935, held by APOTEX INC, supplied as TABLET for ORAL administration. Health Canada currently lists it as dormant, status dated 04-Aug-2017. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is APO-METHIMAZOLE used for?
Medical treatment of hyperthyroidism; preparation for subtotal thyroidectomy or radioactive iodine therapy; use when thyroidectomy is contraindicated or not advisable.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
Product details and regulatory record
| DIN | 02258935 |
|---|---|
| Brand name | APO-METHIMAZOLE |
| Generic / active ingredient | METHIMAZOLE : 5 MG |
| Manufacturer | APOTEX INC |
| Strength | 5 MG |
| Dosage form | TABLET |
| Route of administration | ORAL |
| Schedule | Prescription |
| ATC code | H03BB02 THIAMAZOLE |
| AHFS class | 68:36.08 |
| Biosimilar | No |
| Health Canada status | DORMANT |
| Status date | 04-Aug-2017 |
| Original market date | 2005-03-18 00:00:00 |
How is it administered?
Adults: Initial daily dose 15-60 mg divided into three doses at 8-hour intervals. Maintenance: 5-15 mg daily. Administered orally.
Included because it drives pack selection and wastage. Consult the monograph.
How is it stored and handled?
Store at room temperature (15°C to 30°C). Preserve in well-closed, light-resistant containers.
How is it supplied?
Bottles of 100 tablets.
Contraindications
Hypersensitivity to methimazole or any ingredient; breastfeeding women; history of acute pancreatitis after administration of methimazole.
Warnings and precautions
Serious: Agranulocytosis and liver toxicity. Risk of vasculitis, acute pancreatitis, and hypothyroidism. Contains lactose. Exercise caution when driving/operating machinery.
What can be used instead?
Other Canadian products sharing ATC code H03BB02 THIAMAZOLE. 4 of 14 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.
| Product | Strength | Form | Manufacturer | Health Canada status | DIN |
|---|---|---|---|---|---|
| JAMP METHIMAZOLE | 10 MG | TABLET | JAMP PHARMA CORPORATION | MARKETED | DIN 02490633 |
| JAMP METHIMAZOLE | 5 MG | TABLET | JAMP PHARMA CORPORATION | MARKETED | DIN 02490625 |
| MAR-METHIMAZOLE | 10 MG | TABLET | MARCAN PHARMACEUTICALS INC | MARKETED | DIN 02480115 |
| MAR-METHIMAZOLE | 5 MG | TABLET | MARCAN PHARMACEUTICALS INC | MARKETED | DIN 02480107 |
| DOM-METHIMAZOLE | 5 MG | TABLET | DOMINION PHARMACAL | CANCELLED PRE MARKET | DIN 02265869 |
| METHIMAZOLE TABLETS USP | 10 MG | TABLET | ENDO OPERATIONS LTD. | CANCELLED PRE MARKET | DIN 02489724 |
| METHIMAZOLE TABLETS USP | 20 MG | TABLET | ENDO OPERATIONS LTD. | CANCELLED PRE MARKET | DIN 02489732 |
| METHIMAZOLE TABLETS USP | 5 MG | TABLET | ENDO OPERATIONS LTD. | CANCELLED PRE MARKET | DIN 02489716 |
| PHL-METHIMAZOLE | 5 MG | TABLET | PHARMEL INC | CANCELLED PRE MARKET | DIN 02265850 |
| PMS-METHIMAZOLE | 5 MG | TABLET | PHARMASCIENCE INC | CANCELLED POST MARKET | DIN 02244323 |
Who else supplies THIAMAZOLE worldwide?
Nexara tracks national medicine registries and published price lists across multiple markets. THIAMAZOLE appears in 22 registered pack listings across 7 markets, published on 7 different national price bases. Where a Canadian route is closed, that is where an alternative route of supply starts — subject to the import rules in both countries.
Registered listings are not stock. Ask us to confirm what can actually be sourced for your order.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.