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ALLERGY EYE DROPS 0.25 % — DIN 02248660

ZINC SULFATE : 0.25 % TETRAHYDROZOLINE HYDROCHLORIDE : 0.05 % · ALCON CANADA INC · DROPS · wholesale supply in Canada

Health Canada status: CANCELLED POST MARKET

What is ALLERGY EYE DROPS?

ALLERGY EYE DROPS 0.25 % contains ZINC SULFATE : 0.25 % TETRAHYDROZOLINE HYDROCHLORIDE : 0.05 %. It is listed in the Health Canada Drug Product Database under DIN 02248660, held by ALCON CANADA INC, supplied as DROPS for OPHTHALMIC administration. Health Canada currently lists it as cancelled post market, status dated 24-Apr-2009. This Drug Identification Number is no longer authorized for sale in Canada, so Nexara does not supply it. The record is kept here because buyers still meet the number on old formularies, purchase orders and tender documents; Nexara can help identify an authorized alternative.

How much does Tetryzoline, Combinations cost around the world?

Tetryzoline, Combinations is listed on 4 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.

What a market publishes matters more than the number it publishes. Austria publishes a KVP (Kassenverkaufspreis); Czechia publishes a max producer price (ex-factory); Luxembourg publishes a reimbursement. Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.

MarketPrice basis published thereBrandsPacks listedRange
Romaniamax producer price6496RON███.██
AustriaKVP (Kassenverkaufspreis)33EUR███.██
Czechiamax producer price (ex-factory)23CZK███.██
Luxembourgreimbursement33EUR███.██

105 pack listings across 72 brand entries and 4 price bases, refreshed 05 Sep 2026. Ranges span every Tetryzoline, Combinations pack in that market, so a high figure is usually a larger pack rather than the same product.

Figures are held for the Nexara team. Cross-market prices are published on incompatible bases and are not an offer, a landed cost, or a guide to what any buyer can obtain. Nexara publishes which markets list the product and on what basis; the numbers stay internal.

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This table is a regulatory record of where the molecule is listed. The DIN on this page is no longer authorized for sale in Canada, so Nexara does not quote it — see the alternatives above.

Is there a generic Tetryzoline, Combinations in Canada, and who makes it?

Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.

8 holders have a Canadian DIN containing Tetryzoline, Combinations, across 19 DINs, of which 8 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.

Market authorization holderDINsMarketedBrand namesPosition
JOHNSON & JOHNSON INC84RED EYE TRIPLE ACTION, RED EYE WORKPLACE, VISINE COOL, VISINE FOR ALLERGY 3 SYMPTOM RELIEF, VISINE FOR RED EYE COOL, +3 moreSourceable in Canada
JUNO OTC INC338-SYMPTOM RELIEF, ADVANCED RELIEF EYE DROPS, ALLERGY EYE DROPSSourceable in Canada
PRESTIGE BRANDS INC11CLEAR EYES TRIPLE ACTION RELIEFSourceable in Canada
KC PHARMACEUTICALS INC20ADVANCED RELIEF EYE DROPS, ALLERGY EYE DROPSNo marketed DIN
PFIZER CANADA INC., CONSUMER HEALTHCARE DIVISION20VISINE A.C. OPHTHALMIC SOL, VISINE EXTRA OPHTHALMIC SOLNo marketed DIN
ALCON CANADA INC10ALLERGY EYE DROPSNo marketed DIN
LABORATOIRES CHARTON LABORATORIES10COLLYRIUM EYE DROPSNo marketed DIN
WYETH-AYERST CANADA INC.10COLLYRIUM EYE DROPSNo marketed DIN

Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.

How is it supplied and stored?

Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.

Strength on the label0.25 %
Dosage formDROPS
RouteOPHTHALMIC

Pack detail is kept as a regulatory record. This DIN is no longer authorized for sale in Canada, so Nexara does not quote this pack.

Substance and classification

Active substanceTetryzoline, Combinations
ATC codeS01GA52
AHFS class52:32.00
Biosimilar biologicNo

Health Canada record and identifiers

The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.

DIN (8-digit, as used in ordering)02248660
DIN (unpadded, as printed on some documents)2248660
Brand nameALLERGY EYE DROPS
Generic / active ingredientZINC SULFATE : 0.25 % TETRAHYDROZOLINE HYDROCHLORIDE : 0.05 %
Market authorization holderALCON CANADA INC
Health Canada scheduleNON-PRESCRIPTION DRUGS
ATC codeS01GA52
ATC anatomical main groupS — Sensory organs
ATC therapeutic subgroupS01GA
Current statusCANCELLED POST MARKET
Status date24-Apr-2009
Original market date2005-06-24 00:00:00
Status sourceLive Health Canada DPD sync

Verify on the primary sources

Health Canada DPD record

What can be used instead?

Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.

1 · Same molecule, other Canadian presentations

8 of 19 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.

ProductStrengthFormHolderHealth Canada statusDIN
8-SYMPTOM RELIEF0.25 %SOLUTIONJUNO OTC INCMARKETED02448955
ADVANCED RELIEF EYE DROPS1 %SOLUTIONJUNO OTC INCMARKETED02344319
ALLERGY EYE DROPS0.05 %SOLUTIONJUNO OTC INCMARKETED02290596
CLEAR EYES TRIPLE ACTION RELIEF0.6 %SOLUTIONPRESTIGE BRANDS INCMARKETED02301687
RED EYE TRIPLE ACTION1 %DROPSJOHNSON & JOHNSON INCMARKETED02518201
RED EYE WORKPLACE0.05 %DROPSJOHNSON & JOHNSON INCMARKETED02518228
VISINE FOR ALLERGY 3 SYMPTOM RELIEF0.25 %DROPSJOHNSON & JOHNSON INCMARKETED02144093
VISINE MULTI-SYMPTOM0.25 %DROPSJOHNSON & JOHNSON INCMARKETED02338602
ADVANCED RELIEF EYE DROPS0.1 %SOLUTIONKC PHARMACEUTICALS INCAPPROVED02455293
ALLERGY EYE DROPS0.25 %SOLUTIONKC PHARMACEUTICALS INCAPPROVED02455285

2 · Same class — other molecules in ATC S01GA

MoleculeCanadian brandsDINsMarketedSourceable
Tetryzoline, Combinations8-SYMPTOM RELIEF · ADVANCED RELIEF EYE DROPS · ALLERGY EYE DROPS · CLEAR EYES TRIPLE ACTION RELIEF · +11 more198Yes
Naphazoline, CombinationsALBALON A · ALLERGY EYE DROPS · BLUE COLLYRIUM · CLEAR EYES ACR BY MURINE · +16 more215Yes
NaphazolineALBALON · CLEAR EYES · CLEAR EYES BY MURINE EYE DPS · COLLYRE BLEU LAITER · +12 more162Yes
TetryzolineEYE DROPS · EYE DROPS 0.5MG/ML · ORIGINAL EYE DROPS · R.O.-EYE DROPS · +1 more62Yes
Phenylephrine, CombinationsDIOROUGE LIQ · OCCU-CAL DROPS · OCCU-CAL LOTION · ODAN-VERNACON · +3 more70Not in Canada
OxymetazolineCLARITIN EYE ALLERGY RELIEF · OCUCLEAR OPH DPS 0.025% · VISINE L.R. OPHTHALMIC SOL 0.025% · VISINE WORKPLACE40Not in Canada
PhenylephrinePREFRIN LIQ 0.12%10Not in Canada
Xylomethazoline, CombinationsOPHTRIVIN A OPHTHALMIC DPS10Not in Canada

A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.

3 · Adjacent classes in ATC S01G

ATC subgroupMoleculesDINsMarketed
S01GXCromoglicic Acid · Emedastine · Ketotifen · Levocabastine · Lodoxamide · +2 more3513

Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.

What else is ALLERGY EYE DROPS called?

The same molecule, Tetryzoline, Combinations, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:

NameScriptRegistered in
NUTRIFLEX OMEGA PERI NOVOLatinRomania
NUTRIFLEX OMEGA PLUS NOVOLatinRomania
NUTRIFLEX OMEGA SPECIAL NOVOLatinRomania
SMOFKABIVEN CENTRAL FARA ELECTROLITILatinRomania
FORTRANSLatinRomania
KABIVENLatinRomania
KABIVEN PERIPHERALLatinRomania
SMOFKABIVEN CENTRALLatinRomania
SMOFKABIVEN EXTRA NITROGENLatinRomania
SMOFKABIVEN LOW OSMO PERIPHERALLatinRomania
SMOFKABIVEN PERIPHERALLatinRomania
SOLUTIE RINGER INFOMEDLatinRomania
SOLUTIE RINGER LACTAT INFOMEDLatinRomania
SOLUTIE RINGER LACTAT VIOSERLatinRomania
SOLUTIE RINGER VIOSERLatinRomania

Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.

Can this still be bought in Canada?

No. This Drug Identification Number is cancelled post market in Health Canada's Drug Product Database, so the product is no longer authorized for sale in Canada and Nexara does not supply it. This page is kept as a regulatory record.

If you are looking for a current equivalent, the alternatives above list every product sharing this therapeutic class, with the marketed ones first. Ask us to source an alternative

Ordering questions

Who can buy this from Nexara?

Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.

Is there a minimum order?

Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.

What is the lead time?

Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.

Why is there no price on this page?

Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.

Can Nexara supply this for a clinical trial?

Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.

Sources and disclaimer

Product data sourced from the Health Canada Drug Product Database. Health Canada status reconciled against the live DPD sync. Last reviewed 11 Sep 2026.

Nothing on this page is medical advice. Nexara Health is a licensed wholesale distributor and supplies licensed entities only; consumer orders are routed to a partner pharmacy. Alternatives tables describe supply, not clinical equivalence.

Health Canada Drug Product Database (DPD), DIN 02248660. Last reviewed 2026-09-11. Nexara Health is a licensed wholesaler and supplies licensed entities only; consumer orders are routed to a partner pharmacy.