ALFENTANIL INJECTION USP 500 MCG — DIN 02248181
ALFENTANIL (ALFENTANIL HYDROCHLORIDE) : 500 MCG · SANDOZ CANADA INCORPORATED · SOLUTION · wholesale supply in Canada
Health Canada status: CANCELLED POST MARKET
What is ALFENTANIL INJECTION USP?
ALFENTANIL INJECTION USP 500 MCG contains ALFENTANIL (ALFENTANIL HYDROCHLORIDE) : 500 MCG. It is listed in the Health Canada Drug Product Database under DIN 02248181, held by SANDOZ CANADA INCORPORATED, supplied as SOLUTION for INTRAVENOUS administration. Health Canada currently lists it as cancelled post market, status dated 01-Aug-2019. This Drug Identification Number is no longer authorized for sale in Canada, so Nexara does not supply it. The record is kept here because buyers still meet the number on old formularies, purchase orders and tender documents; Nexara can help identify an authorized alternative.
What is ALFENTANIL INJECTION USP used for?
For Surgical Patients: As an analgesic adjunct to a barbiturate induction agent during short procedures; as an analgesic adjunct to barbiturate/nitrous oxide/oxygen anesthesia when given in incremental doses for the maintenance of anesthesia at dosages of 5-75 mcg/kg in surgical procedures with an expected duration of up to one hour; as an analgesic adjunct given as a continuous infusion at a rate of 0.5 to 1.5 mcg/kg/min with nitrous oxide/oxygen in the maintenance of general anesthesia. For Mechanically Ventilated Patients in the Intensive Care Unit: As an analgesic and suppressant of respiratory drive, to aid compliance with the ventilator and to facilitate toleration of the endotracheal tube, when given as a continuous infusion; as an additional analgesic during brief painful procedures, when given in bolus doses to supplement continuous infusion.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
How much does Alfentanil cost around the world?
Alfentanil is listed on 4 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Iceland publishes a max wholesale; Saudi Arabia publishes a public; South Africa publishes a single exit price. Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| United Kingdom | hospital | 5 | 5 | GBP███.██ |
| Saudi Arabia | public | 1 | 2 | SAR███.██ |
| Iceland | max wholesale | 1 | 1 | ISK███.██ |
| South Africa | single exit price | 1 | 1 | ZAR███.██ |
9 pack listings across 8 brand entries and 4 price bases, refreshed 02 Sep 2026. Ranges span every Alfentanil pack in that market, so a high figure is usually a larger pack rather than the same product.
This table is a regulatory record of where the molecule is listed. The DIN on this page is no longer authorized for sale in Canada, so Nexara does not quote it — see the alternatives above.
Is there a generic Alfentanil in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
2 holders have a Canadian DIN containing Alfentanil, across 2 DINs, of which 0 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| JANSSEN INC | 1 | 0 | ALFENTA INJ 500MCG/ML | No marketed DIN |
| SANDOZ CANADA INCORPORATED | 1 | 0 | ALFENTANIL INJECTION USP | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 500 MCG |
|---|---|
| Dosage form | SOLUTION |
| Route | INTRAVENOUS |
| Pack configuration (monograph) | 2 mL amber vials (boxes of 10) |
| Storage | null |
Pack detail is kept as a regulatory record. This DIN is no longer authorized for sale in Canada, so Nexara does not quote this pack.
Substance and classification
| Active substance | Alfentanil |
|---|---|
| ATC code | N01AH02 |
| AHFS class | 28:08.08 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02248181 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2248181 |
| Brand name | ALFENTANIL INJECTION USP |
| Generic / active ingredient | ALFENTANIL (ALFENTANIL HYDROCHLORIDE) : 500 MCG |
| Market authorization holder | SANDOZ CANADA INCORPORATED |
| Health Canada schedule | NARCOTICS (CDSA I) |
| ATC code | N01AH02 |
| ATC anatomical main group | N — Nervous system |
| ATC therapeutic subgroup | N01AH |
| Current status | CANCELLED POST MARKET |
| Status date | 01-Aug-2019 |
| Original market date | 2004-11-01 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
0 of 2 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| ALFENTA INJ 500MCG/ML | 500 MCG | SOLUTION | JANSSEN INC | CANCELLED POST MARKET | 00755818 |
2 · Same class — other molecules in ATC N01AH
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Fentanyl | FENTANYL CITRATE INJECTION · FENTANYL CITRATE INJECTION SDZ · FENTANYL CITRATE INJECTION U.S.P.-LIQ IV IM EPD · FENTANYL CITRATE INJECTION USP · +4 more | 13 | 8 | Yes |
| Remifentanil | REMIFENTANIL FOR INJECTION · REMIFENTANIL HYDROCHLORIDE FOR INJECTION · ULTIVA | 10 | 2 | Yes |
| Sufentanil | SUFENTA INJ 50MCG/ML · SUFENTANIL CITRATE INJECTION · SUFENTANIL CITRATE INJECTION USP | 5 | 2 | Yes |
| Alfentanil | ALFENTA INJ 500MCG/ML · ALFENTANIL INJECTION USP | 2 | 0 | Not in Canada |
| Anileridine | LERITINE INJ 25MG/ML · LERITINE TABLETS 25MG | 2 | 0 | Not in Canada |
| Fentanyl, Combinations | INNOVAR INJ | 1 | 0 | Not in Canada |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC N01A
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| N01AX | Droperidol · Etomidate · Ketamine · Nitrous Oxide · Nitrous Oxide,Combinations · +1 more | 38 | 19 |
| N01AB | Desflurane · Enflurane · Halothane · Isoflurane · Sevoflurane | 19 | 6 |
| N01AF | Methohexital · Thiopental | 6 | 0 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is ALFENTANIL INJECTION USP called?
The same molecule, Alfentanil, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| Rapifen | Latin | Iceland |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
Can this still be bought in Canada?
No. This Drug Identification Number is cancelled post market in Health Canada's Drug Product Database, so the product is no longer authorized for sale in Canada and Nexara does not supply it. This page is kept as a regulatory record.
If you are looking for a current equivalent, the alternatives above list every product sharing this therapeutic class, with the marketed ones first. Ask us to source an alternative
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.