APO-CALCITONIN NASAL SPRAY 200 UNIT — DIN 02247585
CALCITONIN (SALMON SYNTHETIC) : 200 UNIT · APOTEX INC · SOLUTION · wholesale supply in Canada
Health Canada status: CANCELLED POST MARKET
What is APO-CALCITONIN NASAL SPRAY?
APO-CALCITONIN NASAL SPRAY 200 UNIT contains CALCITONIN (SALMON SYNTHETIC) : 200 UNIT. It is listed in the Health Canada Drug Product Database under DIN 02247585, held by APOTEX INC, supplied as SOLUTION for NASAL administration. Health Canada currently lists it as cancelled post market, status dated 01-Oct-2013. This Drug Identification Number is no longer authorized for sale in Canada, so Nexara does not supply it. The record is kept here because buyers still meet the number on old formularies, purchase orders and tender documents; Nexara can help identify an authorized alternative.
What is APO-CALCITONIN NASAL SPRAY used for?
Treatment of postmenopausal osteoporosis in females >5 years postmenopause with low bone mass who cannot tolerate estrogens. Used with calcium (1000 mg) and Vitamin D (400 IU).
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
Is there a generic Calcitonin (Salmon Synthetic) in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
7 holders have a Canadian DIN containing Calcitonin (Salmon Synthetic), across 10 DINs, of which 1 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| SANOFI-AVENTIS CANADA INC | 1 | 1 | CALCIMAR | Sourceable in Canada |
| APOTEX INC | 2 | 0 | APO-CALCITONIN INJECTABLE, APO-CALCITONIN NASAL SPRAY | No marketed DIN |
| FERRING INC | 2 | 0 | CALTINE INJ 100 UNIT/ML (1ML AMP), CALTINE INJ 100UNIT/ML (0.5ML AMP) | No marketed DIN |
| NOVARTIS PHARMACEUTICALS CANADA INC | 2 | 0 | MIACALCIN INJECTION 200IU/ML, MIACALCIN NASAL SPRAY 200 IU | No marketed DIN |
| PRO DOC LIMITEE | 1 | 0 | PRO-CALCITONIN - 200 | No marketed DIN |
| SANDOZ CANADA INCORPORATED | 1 | 0 | SANDOZ-CALCITONIN NS | No marketed DIN |
| STERIMAX INC | 1 | 0 | CALCITONIN SALMON INJECTION USP | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 200 UNIT |
|---|---|
| Dosage form | SOLUTION |
| Route | NASAL |
| Pack configuration (monograph) | Packs containing two (2) clear glass bottles (Type I) with metered nasal spray pump, delivering at least 14 doses of 200 IU each. |
| Storage | Unopened: Refrigerate (2-8°C). Protect from freezing. Opened/Primed: Store at room temperature (below 25°C) upright; use within 4 weeks. |
| Shipping class | Cold chain — validated shipper with temperature monitoring |
Pack detail is kept as a regulatory record. This DIN is no longer authorized for sale in Canada, so Nexara does not quote this pack.
Substance and classification
| Active substance | Calcitonin (Salmon Synthetic) |
|---|---|
| ATC code | H05BA01 |
| AHFS class | 68:24.00 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02247585 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2247585 |
| Brand name | APO-CALCITONIN NASAL SPRAY |
| Generic / active ingredient | CALCITONIN (SALMON SYNTHETIC) : 200 UNIT |
| Market authorization holder | APOTEX INC |
| Health Canada schedule | Prescription |
| ATC code | H05BA01 |
| ATC anatomical main group | H — Systemic hormonal preparations |
| ATC therapeutic subgroup | H05BA |
| Current status | CANCELLED POST MARKET |
| Status date | 01-Oct-2013 |
| Original market date | 2003-09-12 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
How is it administered?
One spray (200 IU) per day administered intranasally, alternating nostrils daily. Pump must be primed before first use.
Included because it drives pack selection and wastage. Consult the monograph.
Contraindications
Known hypersensitivity to salmon calcitonin or to any component of the formulation.
Warnings and precautions
Possibility of systemic allergic reactions (bronchospasm, anaphylaxis). Perform nasal examination before and during treatment; discontinue if severe mucosal ulceration occurs.
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
1 of 10 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| CALCIMAR | 200 UNIT | SOLUTION | SANOFI-AVENTIS CANADA INC | MARKETED | 01926691 |
| APO-CALCITONIN INJECTABLE | 200 UNIT | LIQUID | APOTEX INC | CANCELLED POST MARKET | 02246058 |
| CALCITONIN SALMON INJECTION USP | 200 UNIT | SOLUTION | STERIMAX INC | APPROVED | 02383233 |
| CALTINE INJ 100 UNIT/ML (1ML AMP) | 100 UNIT | LIQUID | FERRING INC | CANCELLED POST MARKET | 02007134 |
| CALTINE INJ 100UNIT/ML (0.5ML AMP) | 100 UNIT | LIQUID | FERRING INC | CANCELLED POST MARKET | 01940376 |
| MIACALCIN INJECTION 200IU/ML | 200 UNIT | LIQUID | NOVARTIS PHARMACEUTICALS CANADA INC | APPROVED | 02144301 |
| MIACALCIN NASAL SPRAY 200 IU | 200 UNIT | SPRAY | NOVARTIS PHARMACEUTICALS CANADA INC | CANCELLED POST MARKET | 02240775 |
| PRO-CALCITONIN - 200 | 200 UNIT | SOLUTION | PRO DOC LIMITEE | CANCELLED POST MARKET | 02311046 |
| SANDOZ-CALCITONIN NS | 200 UNIT | LIQUID | SANDOZ CANADA INCORPORATED | CANCELLED POST MARKET | 02261766 |
2 · Same class — other molecules in ATC H05BA
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Calcitonin (Salmon Synthetic) | APO-CALCITONIN INJECTABLE · APO-CALCITONIN NASAL SPRAY · CALCIMAR · CALCITONIN SALMON INJECTION USP · +6 more | 10 | 1 | Yes |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC H05B
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| H05BX | Cinacalcet · Doxercalciferol · Paricalcitol | 47 | 22 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
Can this still be bought in Canada?
No. This Drug Identification Number is cancelled post market in Health Canada's Drug Product Database, so the product is no longer authorized for sale in Canada and Nexara does not supply it. This page is kept as a regulatory record.
If you are looking for a current equivalent, the alternatives above list every product sharing this therapeutic class, with the marketed ones first. Ask us to source an alternative
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.