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TRACLEER 125 MG

BOSENTAN (BOSENTAN MONOHYDRATE) : 125 MG · DIN 02244982 · JANSSEN INC

Health Canada status: MARKETED

What is TRACLEER?

TRACLEER 125 MG contains BOSENTAN (BOSENTAN MONOHYDRATE) : 125 MG. It is listed in the Health Canada Drug Product Database under DIN 02244982, held by JANSSEN INC, supplied as TABLET for ORAL administration. Health Canada currently lists it as marketed, status dated 18-Oct-2019. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.

What else is TRACLEER called?

The same molecule, BOSENTAN, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:

NameScriptRegistered in
Bosentan APOLatinAustralia
BOSENTAN DR.REDDY'SLatinAustralia
Bosentan RBXLatinAustralia
Bosentan GHLatinAustralia
Bosentan ViatrisLatinAustralia
Bosentan AccordLatinSweden
Bosentan AurobindoLatinSweden
Bosentan OHRE PharmaLatinSaudi Arabia
Bosentan SandozLatinSweden
BosfitLatinSaudi Arabia
STAYVEERLatinSweden

Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.

Product details and regulatory record

DIN02244982
Brand nameTRACLEER
Generic / active ingredientBOSENTAN (BOSENTAN MONOHYDRATE) : 125 MG
ManufacturerJANSSEN INC
Strength125 MG
Dosage formTABLET
Route of administrationORAL
SchedulePrescription
ATC codeC02KX01 BOSENTAN
AHFS class48:48.12
BiosimilarNo
Health Canada statusMARKETED
Status date18-Oct-2019
Original market date2001-12-14 00:00:00

How is this product identified?

Purchase orders, customs paperwork and tender documents each ask for a different identifier, and a DIN written without its leading zeros is the single most common reason an order line fails to match. Every form Nexara accepts for this product is listed here.

DIN (8-digit, as used in Nexara ordering)02244982
DIN (unpadded, as printed on some documents)2244982
Brand nameTRACLEER
Active ingredient / INNBOSENTAN (BOSENTAN MONOHYDRATE) : 125 MG
ATC codeC02KX01
ATC anatomical main groupC — Cardiovascular system
ATC therapeutic subgroupC02
AHFS class48:48.12
Health Canada schedulePrescription
Biosimilar biologicNo
Market authorization holderJANSSEN INC

Health Canada approved product monograph (PDF)

Which pack is which?

Strength on the label125 MG
Dosage formTABLET
RouteORAL

One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced. Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.

Confirm the pack and get a price

What can be used instead?

Other Canadian products sharing ATC code C02KX01 BOSENTAN. 6 of 32 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.

ProductStrengthFormManufacturerHealth Canada statusDIN
PMS-BOSENTAN125 MGTABLETPHARMASCIENCE INCMARKETEDDIN 02383020
PMS-BOSENTAN62.5 MGTABLETPHARMASCIENCE INCMARKETEDDIN 02383012
TARO-BOSENTAN125 MGTABLETTARO PHARMACEUTICALS INCMARKETEDDIN 02483149
TARO-BOSENTAN62.5 MGTABLETTARO PHARMACEUTICALS INCMARKETEDDIN 02483130
TRACLEER62.5 MGTABLETJANSSEN INCMARKETEDDIN 02244981
ACCEL-BOSENTAN125 MGTABLETACCEL PHARMA INCCANCELLED PRE MARKETDIN 02435403
ACT BOSENTAN125 MGTABLETACTAVIS PHARMA COMPANYCANCELLED POST MARKETDIN 02386208
ACT BOSENTAN62.5 MGTABLETACTAVIS PHARMA COMPANYCANCELLED POST MARKETDIN 02386194
ALEMBIC-BOSENTAN125 MGTABLETALEMBIC PHARMACEUTICALS LIMITEDAPPROVEDDIN 02423065
ALEMBIC-BOSENTAN62.5 MGTABLETALEMBIC PHARMACEUTICALS LIMITEDAPPROVEDDIN 02423057

Who else supplies BOSENTAN worldwide?

Nexara tracks national medicine registries and published price lists across multiple markets. BOSENTAN appears in 262 registered pack listings across 13 markets, published on 11 different national price bases. Where a Canadian route is closed, that is where an alternative route of supply starts — subject to the import rules in both countries.

Registered listings are not stock. Ask us to confirm what can actually be sourced for your order.

How much does BOSENTAN cost around the world?

BOSENTAN is listed on 9 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.

What a market publishes matters more than the number it publishes. Australia publishes a ex-manufacturer; Bahrain publishes a retail (max); Greece publishes a producer price (ex-factory). Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.

MarketPrice basis published thereBrandsPacks listedRange
Australiaex-manufacturer544AUD███.██
Saudi Arabiapublic1115SAR███.██
Italyprezzo al pubblico (classe A)614EUR███.██
Greeceproducer price (ex-factory)1313EUR███.██
SwedenAIP (pharmacy purchase price)513SEK███.██
Hungaryproducer price (ex-factory)44HUF███.██
Romaniamax producer price24RON███.██
Bahrainretail (max)13BHD███.██
United Kingdomhospital22GBP███.██
Italyex-factory (classe H)11EUR███.██

113 pack listings across 50 brand entries and 9 price bases, refreshed 08 Sep 2026. Ranges span every BOSENTAN pack in that market, so a high figure is usually a larger pack rather than the same product.

Figures are held for the Nexara team. Cross-market prices are published on incompatible bases and are not an offer, a landed cost, or a guide to what any buyer can obtain. Nexara publishes which markets list the product and on what basis; the numbers stay internal.

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Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.

Ask Nexara for a landed Canadian price

How can I get it?

Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.

Request a quote for TRACLEER

Ordering questions

Who can buy this from Nexara?

Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.

Is there a minimum order?

Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.

What is the lead time?

Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.

Can Nexara supply this for a clinical trial?

Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.

Health Canada Drug Product Database (DPD), DIN 02244982. Last reviewed 2026-09-10. Nexara Health is a licensed wholesaler and supplies licensed entities only; consumer orders are routed to a partner pharmacy.