ACT CLOMIPRAMINE 25 MG — DIN 02244817
CLOMIPRAMINE HYDROCHLORIDE : 25 MG · ACTAVIS PHARMA COMPANY · TABLET · wholesale supply in Canada
Health Canada status: CANCELLED POST MARKET
What is ACT CLOMIPRAMINE?
ACT CLOMIPRAMINE 25 MG contains CLOMIPRAMINE HYDROCHLORIDE : 25 MG. It is listed in the Health Canada Drug Product Database under DIN 02244817, held by ACTAVIS PHARMA COMPANY, supplied as TABLET for ORAL administration. Health Canada currently lists it as cancelled post market, status dated 19-Feb-2016. This Drug Identification Number is no longer authorized for sale in Canada, so Nexara does not supply it. The record is kept here because buyers still meet the number on old formularies, purchase orders and tender documents; Nexara can help identify an authorized alternative.
What is ACT CLOMIPRAMINE used for?
Treatment of depression (including associated anxiety) and obsessions/compulsions in patients with obsessive compulsive disorder (OCD).
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
How much does Clomipramine cost around the world?
Clomipramine is listed on 6 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Australia publishes a ex-manufacturer; Greece publishes a producer price (ex-factory); Morocco publishes a PPV (public price). Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| United States | acquisition | 3 | 55 | USD███.██ |
| South Africa | single exit price | 4 | 7 | ZAR███.██ |
| Australia | ex-manufacturer | 4 | 4 | AUD███.██ |
| United Kingdom | hospital | 3 | 3 | GBP███.██ |
| Greece | producer price (ex-factory) | 3 | 3 | EUR███.██ |
| Morocco | PPV (public price) | 1 | 3 | MAD███.██ |
75 pack listings across 18 brand entries and 6 price bases, refreshed 08 Sep 2026. Ranges span every Clomipramine pack in that market, so a high figure is usually a larger pack rather than the same product.
This table is a regulatory record of where the molecule is listed. The DIN on this page is no longer authorized for sale in Canada, so Nexara does not quote it — see the alternatives above.
Is there a generic Clomipramine in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
13 holders have a Canadian DIN containing Clomipramine, across 35 DINs, of which 5 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| APOTEX INC | 6 | 3 | ANAFRANIL, APO-CLOMIPRAMINE | Sourceable in Canada |
| TARO PHARMACEUTICALS INC | 2 | 2 | TARO-CLOMIPRAMINE | Sourceable in Canada |
| ACTAVIS PHARMA COMPANY | 3 | 0 | ACT CLOMIPRAMINE | No marketed DIN |
| ASPRI PHARMA CANADA INC | 3 | 0 | ALTIUS-CLOMIPRAMINE | No marketed DIN |
| GENPHARM ULC | 3 | 0 | GEN-CLOMIPRAMINE - TAB 10MG, GEN-CLOMIPRAMINE - TAB 25MG, GEN-CLOMIPRAMINE - TAB 50MG | No marketed DIN |
| NOVOPHARM LIMITED | 3 | 0 | NOVO-CLOPAMINE TAB 10MG, NOVO-CLOPAMINE TABLETS - 25MG, NOVO-CLOPAMINE TABLETS- 50MG | No marketed DIN |
| PHARMASCIENCE INC | 3 | 0 | PMS-CLOMIPRAMINE | No marketed DIN |
| PREMPHARM INC | 3 | 0 | CLOMIPRAMINE TABLETS 10MG, CLOMIPRAMINE TABLETS 25MG, CLOMIPRAMINE TABLETS 50MG | No marketed DIN |
| PRO DOC LIMITEE | 3 | 0 | CLOMIPRAMINE-10 - TAB 10MG, CLOMIPRAMINE-25 - TAB 25MG, CLOMIPRAMINE-50 - TAB 50MG | No marketed DIN |
| DOMINION PHARMACAL | 2 | 0 | DOM-CLOMIPRAMINE | No marketed DIN |
| PENTAPHARM LTD. | 2 | 0 | PENTA-CLOMIPRAMINE - 25MG, PENTA-CLOMIPRAMINE - 50MG | No marketed DIN |
| MEDICAN PHARMA INCORPORATED | 1 | 0 | MED CLOMIPRAMINE TABLETS - 25MG | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 25 MG |
|---|---|
| Dosage form | TABLET |
| Route | ORAL |
| Pack configuration (monograph) | Not explicitly stated in provided text (mentions 10 mg, 25 mg, 50 mg strengths). |
| Storage | Not explicitly stated in provided text. |
Pack detail is kept as a regulatory record. This DIN is no longer authorized for sale in Canada, so Nexara does not quote this pack.
Substance and classification
| Active substance | Clomipramine |
|---|---|
| ATC code | N06AA04 |
| AHFS class | 28:16.04.28 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02244817 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2244817 |
| Brand name | ACT CLOMIPRAMINE |
| Generic / active ingredient | CLOMIPRAMINE HYDROCHLORIDE : 25 MG |
| Market authorization holder | ACTAVIS PHARMA COMPANY |
| Health Canada schedule | Prescription |
| ATC code | N06AA04 |
| ATC anatomical main group | N — Nervous system |
| ATC therapeutic subgroup | N06AA |
| Current status | CANCELLED POST MARKET |
| Status date | 19-Feb-2016 |
| Original market date | 2003-02-20 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
How is it administered?
Individualized dosage. Recommended total daily doses should not be exceeded due to seizure risk. Taper gradually when discontinuing. Lower doses required for elderly.
Included because it drives pack selection and wastage. Consult the monograph.
Contraindications
Hypersensitivity to clomipramine or dibenzazepine tricyclics; MAOIs; acute recovery phase after MI; congestive heart failure; liver/kidney damage; blood dyscrasias; glaucoma.
Warnings and precautions
Seizure risk (dose-dependent); cardiovascular effects (QTc prolongation, arrhythmias, tachycardia); suicidal potential; anticholinergic effects; may impair mental/physical abilities.
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
5 of 35 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| ANAFRANIL | 50 MG | TABLET | APOTEX INC | MARKETED | 00402591 |
| ANAFRANIL | 10 MG | TABLET | APOTEX INC | MARKETED | 00330566 |
| ANAFRANIL | 25 MG | TABLET | APOTEX INC | MARKETED | 00324019 |
| TARO-CLOMIPRAMINE | 25 MG | CAPSULE | TARO PHARMACEUTICALS INC | MARKETED | 02497506 |
| TARO-CLOMIPRAMINE | 50 MG | CAPSULE | TARO PHARMACEUTICALS INC | MARKETED | 02497514 |
| ACT CLOMIPRAMINE | 50 MG | TABLET | ACTAVIS PHARMA COMPANY | CANCELLED POST MARKET | 02244818 |
| ACT CLOMIPRAMINE | 10 MG | TABLET | ACTAVIS PHARMA COMPANY | CANCELLED POST MARKET | 02244816 |
| ALTIUS-CLOMIPRAMINE | 50 MG | TABLET | ASPRI PHARMA CANADA INC | CANCELLED PRE MARKET | 02446774 |
| ALTIUS-CLOMIPRAMINE | 10 MG | TABLET | ASPRI PHARMA CANADA INC | CANCELLED PRE MARKET | 02446758 |
| ALTIUS-CLOMIPRAMINE | 25 MG | TABLET | ASPRI PHARMA CANADA INC | CANCELLED PRE MARKET | 02446766 |
2 · Same class — other molecules in ATC N06AA
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Doxepin | ALTI-DOXEPIN - CAP 10MG · ALTI-DOXEPIN-CAP 25MG · ALTI-DOXEPIN-CAP 50MG · ALTI-DOXEPIN-CAP 75MG · +22 more | 51 | 22 | Yes |
| Amitriptyline | AG-AMITRIPTYLINE · AMITRIPTYLINE · AMITRIPTYLINE 10 TAB · AMITRIPTYLINE 25 TAB · +28 more | 83 | 15 | Yes |
| Imipramine | APO-IMIPRAMINE · APO-IMIPRAMINE TABLETS · IMIPRAMINE 10TAB · IMIPRAMINE 25TAB · +16 more | 32 | 8 | Yes |
| Desipramine | DESIPRAMINE · DESIPRAMINE-10 - TAB 10MG · DESIPRAMINE-25 - TAB 25MG · DESIPRAMINE-50 - TAB 50MG · +29 more | 49 | 5 | Yes |
| Clomipramine | ACT CLOMIPRAMINE · ALTIUS-CLOMIPRAMINE · ANAFRANIL · APO-CLOMIPRAMINE · +19 more | 35 | 5 | Yes |
| Trimipramine | APO-TRIMIPRAMINE · NOVO-TRIPRAMINE TAB 100MG BP · NOVO-TRIPRAMINE TAB 25MG BP · NOVO-TRIPRAMINE TAB 50MG BP · +15 more | 32 | 5 | Yes |
| Nortriptyline | APO-NORTRIPTYLINE · AVA-NORTRIPTYLINE · AVENTYL · DOM-NORTRIPTYLINE 10MG CAPSULES · +10 more | 24 | 2 | Yes |
| Maprotiline | LUDIOMIL TAB 10MG · LUDIOMIL TAB 25MG · LUDIOMIL TAB 50MG · LUDIOMIL TAB 75MG · +3 more | 12 | 0 | Not in Canada |
| Amoxapine | ASENDIN - TAB 100MG · ASENDIN - TAB 25MG · ASENDIN - TAB 50MG · ASENDIN TAB 100MG · +2 more | 6 | 0 | Not in Canada |
| Protriptyline | TRIPTIL TAB 10MG | 1 | 0 | Not in Canada |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC N06A
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| N06AB | Citalopram · Escitalopram · Fluoxetine · Fluvoxamine · Paroxetine · +1 more | 589 | 248 |
| N06AX | Bupropion · Desvenlafaxine · Duloxetine · Esketamine · Levomilnacipran · +7 more | 386 | 181 |
| N06AG | Moclobemide | 21 | 4 |
| N06AF | Tranylcypromine | 2 | 2 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is ACT CLOMIPRAMINE called?
The same molecule, Clomipramine, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| Anafranil | Latin | Morocco, South Africa |
| Equinorm | Latin | South Africa |
| APO-Clomipramine | Latin | Australia |
| CLOMIPRAMINE-WGR | Latin | Australia |
| Micro-Clomipramine | Latin | South Africa |
| Placil | Latin | Australia |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
Can this still be bought in Canada?
No. This Drug Identification Number is cancelled post market in Health Canada's Drug Product Database, so the product is no longer authorized for sale in Canada and Nexara does not supply it. This page is kept as a regulatory record.
If you are looking for a current equivalent, the alternatives above list every product sharing this therapeutic class, with the marketed ones first. Ask us to source an alternative
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.