TIMOLOL MALEATE-EX 0.5 %
TIMOLOL (TIMOLOL MALEATE) : 0.5 % · DIN 02242276 · SANDOZ CANADA INCORPORATED
Health Canada status: MARKETED
What is TIMOLOL MALEATE-EX?
TIMOLOL MALEATE-EX 0.5 % contains TIMOLOL (TIMOLOL MALEATE) : 0.5 %. It is listed in the Health Canada Drug Product Database under DIN 02242276, held by SANDOZ CANADA INCORPORATED, supplied as SOLUTION (EXTENDED RELEASE) for OPHTHALMIC administration. Health Canada currently lists it as marketed, status dated 19-May-2017. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is TIMOLOL MALEATE-EX used for?
T-LO is indicated for the reduction of elevated intraocular pressure (IOP) in adult patients with chronic open glaucoma, ocular hypertension, aphakic patients with glaucoma (including those wearing contact lenses), and narrow angles with a history of spontaneous or iatrogenically-induced narrow-angle closure in the opposite eye where IOP reduction is necessary. TIMOLOL MALEATE-EX is indicated for the reduction of IOP in adult patients with chronic open-angle glaucoma and ocular hypertension.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
Product details and regulatory record
| DIN | 02242276 |
|---|---|
| Brand name | TIMOLOL MALEATE-EX |
| Generic / active ingredient | TIMOLOL (TIMOLOL MALEATE) : 0.5 % |
| Manufacturer | SANDOZ CANADA INCORPORATED |
| Strength | 0.5 % |
| Dosage form | SOLUTION (EXTENDED RELEASE) |
| Route of administration | OPHTHALMIC |
| Schedule | Prescription |
| ATC code | S01ED01 TIMOLOL |
| AHFS class | 88:08.00 |
| Biosimilar | No |
| Health Canada status | MARKETED |
| Status date | 19-May-2017 |
| Original market date | 2000-10-24 00:00:00 |
How is it stored and handled?
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How is it supplied?
T - LO, 0.5%, is supplied in 5 mL and 10 mL white, opaque, plastic ophthalmic DROP - TAINER* dispensers with a controlled drop tip, and the 0.25% is supplied in 10 mL. TIMOLOL MALEATE - EX, 0.25% or 0.5%, is supplied in 5 mL white, opaque, plastic ophthalmic DROP - TAINER* dispensers with a controlled drop tip.
Is TIMOLOL in shortage in Canada?
A Canadian shortage report is on file for this molecule: Active — reported by SANDOZ CANADA INCORPORATED, last seen 04 Sep 2026. A shortage on one presentation does not always affect every DIN of the molecule — the alternatives below list what else is marketed in Canada. Nexara can confirm current availability and identify substitutions or import options where permitted.
What can be used instead?
Other Canadian products sharing ATC code S01ED01 TIMOLOL. 7 of 35 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.
| Product | Strength | Form | Manufacturer | Health Canada status | DIN |
|---|---|---|---|---|---|
| JAMP-TIMOLOL | 0.5 % | SOLUTION | JAMP PHARMA CORPORATION | MARKETED | DIN 02447800 |
| SANDOZ TIMOLOL | 0.25 % | SOLUTION | SANDOZ CANADA INCORPORATED | MARKETED | DIN 02166712 |
| SANDOZ TIMOLOL | 0.5 % | SOLUTION | SANDOZ CANADA INCORPORATED | MARKETED | DIN 02166720 |
| TIMOLOL MALEATE-EX | 0.25 % | SOLUTION (EXTENDED RELEASE) | SANDOZ CANADA INCORPORATED | MARKETED | DIN 02242275 |
| TIMOPTIC | 0.5 % | SOLUTION | ELVIUM LIFE SCIENCES | MARKETED | DIN 00451207 |
| TIMOPTIC-XE | 0.5 % | SOLUTION (EXTENDED RELEASE) | ELVIUM LIFE SCIENCES | MARKETED | DIN 02171899 |
| APO-TIMOP | 0.25 % | SOLUTION | APOTEX INC | DORMANT | DIN 00755826 |
| APO-TIMOP | 0.5 % | SOLUTION | APOTEX INC | DORMANT | DIN 00755834 |
| APO-TIMOP GEL | 0.25 % | SOLUTION (EXTENDED RELEASE) | APOTEX INC | APPROVED | DIN 02315858 |
| APO-TIMOP GEL | 0.5 % | SOLUTION (EXTENDED RELEASE) | APOTEX INC | DORMANT | DIN 02290812 |
Who else supplies TIMOLOL worldwide?
Nexara tracks national medicine registries and published price lists across multiple markets. TIMOLOL appears in 178 registered pack listings across 10 markets, published on 8 different national price bases. Where a Canadian route is closed, that is where an alternative route of supply starts — subject to the import rules in both countries.
Registered listings are not stock. Ask us to confirm what can actually be sourced for your order.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.