MARCAINE E 0.182 MG / 20 ML
EPINEPHRINE BITARTRATE : 0.182 MG / 20 ML BUPIVACAINE HYDROCHLORIDE : 100 MG / 20 ML · DIN 02241916 · PFIZER CANADA ULC
Health Canada status: MARKETED
What is MARCAINE E?
MARCAINE E 0.182 MG / 20 ML contains EPINEPHRINE BITARTRATE : 0.182 MG / 20 ML BUPIVACAINE HYDROCHLORIDE : 100 MG / 20 ML. It is listed in the Health Canada Drug Product Database under DIN 02241916, held by PFIZER CANADA ULC, supplied as SOLUTION for BLOCK/INFILTRATION ; EPIDURAL administration. Health Canada currently lists it as marketed, status dated 07-Sep-2017. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
Product details and regulatory record
| DIN | 02241916 |
|---|---|
| Brand name | MARCAINE E |
| Generic / active ingredient | EPINEPHRINE BITARTRATE : 0.182 MG / 20 ML BUPIVACAINE HYDROCHLORIDE : 100 MG / 20 ML |
| Manufacturer | PFIZER CANADA ULC |
| Strength | 0.182 MG / 20 ML |
| Dosage form | SOLUTION |
| Route of administration | BLOCK/INFILTRATION ; EPIDURAL |
| Schedule | Ethical |
| ATC code | N01BB51 BUPIVACAINE, COMBINATIONS |
| AHFS class | 72:00.00 |
| Biosimilar | No |
| Health Canada status | MARKETED |
| Status date | 07-Sep-2017 |
| Original market date | 2001-07-15 00:00:00 |
How is this product identified?
Purchase orders, customs paperwork and tender documents each ask for a different identifier, and a DIN written without its leading zeros is the single most common reason an order line fails to match. Every form Nexara accepts for this product is listed here.
| DIN (8-digit, as used in Nexara ordering) | 02241916 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2241916 |
| Brand name | MARCAINE E |
| Active ingredient / INN | EPINEPHRINE BITARTRATE : 0.182 MG / 20 ML BUPIVACAINE HYDROCHLORIDE : 100 MG / 20 ML |
| ATC code | N01BB51 |
| ATC anatomical main group | N — Nervous system |
| ATC therapeutic subgroup | N01 |
| AHFS class | 72:00.00 |
| Health Canada schedule | Ethical |
| Biosimilar biologic | No |
| Market authorization holder | PFIZER CANADA ULC |
Which pack is which?
| Strength on the label | 0.182 MG / 20 ML |
|---|---|
| Dosage form | SOLUTION |
| Route | BLOCK/INFILTRATION ; EPIDURAL |
One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced. Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation, because this listing covers more than one of them.
What can be used instead?
Other Canadian products sharing ATC code N01BB51 BUPIVACAINE, COMBINATIONS. 5 of 12 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.
| Product | Strength | Form | Manufacturer | Health Canada status | DIN |
|---|---|---|---|---|---|
| MARCAINE | 5 MG | SOLUTION | SEPTODONT INC | MARKETED | DIN 02474247 |
| MARCAINE E | 50 MG / 20 ML | SOLUTION | PFIZER CANADA ULC | MARKETED | DIN 02241915 |
| SENSORCAINE WITH EPINEPHRINE | 2.5 MG | SOLUTION | ASPEN PHARMACARE CANADA INC. | MARKETED | DIN 01976184 |
| SENSORCAINE WITH EPINEPHRINE | 5 MG | SOLUTION | ASPEN PHARMACARE CANADA INC. | MARKETED | DIN 01976206 |
| BUPIVACAINE HCL 0.5% AND EPINEPHRINE 1:200,000 INJECTION | 5 MG | SOLUTION | NOVOCOL PHARMACEUTICAL OF CANADA INC | DORMANT | DIN 02381850 |
| MARCAINE | 0.0091 MG | SOLUTION | CARESTREAM HEALTH CANADA COMPANY | CANCELLED POST MARKET | DIN 02311887 |
| MARCAINE 0.5% AND EPINEPHRINE 1:200,000 LIQ | 9.1 MCG | LIQUID | KODAK CANADA INC. | CANCELLED POST MARKET | DIN 01990616 |
| MARCAINE E 0.25% LIQ PRT | 2.5 MG | LIQUID | SANOFI CANADA, INC. | CANCELLED POST MARKET | DIN 02018322 |
| MARCAINE E LIQ PRT 0.50% | 9.1 MCG | LIQUID | SANOFI CANADA, INC. | CANCELLED POST MARKET | DIN 02018330 |
| SENSORCAINE FORTE | 5 MG | SOLUTION | DENTSPLY CANADA LIMITED | CANCELLED POST MARKET | DIN 01976214 |
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.