DIFFERIN 0.1 %
ADAPALENE : 0.1 % · DIN 02231592 · GALDERMA CANADA INC
Health Canada status: MARKETED
What is DIFFERIN?
DIFFERIN 0.1 % contains ADAPALENE : 0.1 %. It is listed in the Health Canada Drug Product Database under DIN 02231592, held by GALDERMA CANADA INC, supplied as CREAM for TOPICAL administration. Health Canada currently lists it as marketed, status dated 08-Jan-1998. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is DIFFERIN used for?
Treatment of acne vulgaris in patients 12 years of age and older.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
Product details and regulatory record
| DIN | 02231592 |
|---|---|
| Brand name | DIFFERIN |
| Generic / active ingredient | ADAPALENE : 0.1 % |
| Manufacturer | GALDERMA CANADA INC |
| Strength | 0.1 % |
| Dosage form | CREAM |
| Route of administration | TOPICAL |
| Schedule | Prescription |
| ATC code | D10AD03 ADAPALENE |
| AHFS class | 84:04.92 |
| Biosimilar | No |
| Health Canada status | MARKETED |
| Status date | 08-Jan-1998 |
| Original market date | 1998-08-26 00:00:00 |
How is it administered?
Apply a thin film to affected areas of face, chest, and back once daily before retiring and after washing. Ensure skin is dry. Avoid eyes, lips, and mucous membranes.
Included because it drives pack selection and wastage. Consult the monograph.
How is it stored and handled?
Not explicitly detailed in the provided text sections (refer to section 11).
How is it supplied?
60 g laminate tubes (Cream, Gel 0.1%, Gel 0.3%); 60 mL and 120 mL HDPE bottles with pump (Lotion 0.1%).
Contraindications
Hypersensitivity to ingredients; patients with eczema or seborrheic dermatitis; pregnancy; women planning a pregnancy.
Warnings and precautions
For external use only. Avoid excessive sunlight/UV exposure. Use sunscreen. Avoid "waxing" on treated skin. May cause local irritation (erythema, dryness, burning).
What can be used instead?
Other Canadian products sharing ATC code D10AD03 ADAPALENE. 3 of 5 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.
| Product | Strength | Form | Manufacturer | Health Canada status | DIN |
|---|---|---|---|---|---|
| DIFFERIN | 0.1 % | GEL | GALDERMA CANADA INC | MARKETED | DIN 02148749 |
| DIFFERIN XP | 0.3 % | GEL | GALDERMA CANADA INC | MARKETED | DIN 02274000 |
| DIFFERIN | 0.1 % | LIQUID | GALDERMA CANADA INC | CANCELLED POST MARKET | DIN 02148757 |
| DIFFERIN | 0.1 % | LOTION | GALDERMA CANADA INC | APPROVED | DIN 02376660 |
Who else supplies ADAPALENE worldwide?
Nexara tracks national medicine registries and published price lists across multiple markets. ADAPALENE appears in 2012 registered pack listings across 7 markets, published on 6 different national price bases. Where a Canadian route is closed, that is where an alternative route of supply starts — subject to the import rules in both countries.
Registered listings are not stock. Ask us to confirm what can actually be sourced for your order.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.