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SUPREFACT 100 MCG

BUSERELIN (BUSERELIN ACETATE) : 100 MCG · DIN 02225158 · CHEPLAPHARM ARZNEIMITTEL GMBH

Health Canada status: CANCELLED POST MARKET

What is SUPREFACT?

SUPREFACT 100 MCG contains BUSERELIN (BUSERELIN ACETATE) : 100 MCG. It is listed in the Health Canada Drug Product Database under DIN 02225158, held by CHEPLAPHARM ARZNEIMITTEL GMBH, supplied as SOLUTION for NASAL administration. Health Canada currently lists it as cancelled post market, status dated 29-Apr-2022. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.

What is SUPREFACT used for?

SUPREFACT (buserelin acetate) is indicated for: Subcutaneous injection: The palliative treatment (initial and maintenance treatment) of patients with hormone-dependent advanced carcinoma of the prostate gland (Stage D). Nasal solution: The palliative treatment (maintenance treatment) of patients with hormone-dependent advanced carcinoma of the prostate gland (Stage D). The treatment of endometriosis in patients who do not require surgery as primary therapy. The duration of treatment is usually six months and should not exceed nine months.

Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.

Product details and regulatory record

DIN02225158
Brand nameSUPREFACT
Generic / active ingredientBUSERELIN (BUSERELIN ACETATE) : 100 MCG
ManufacturerCHEPLAPHARM ARZNEIMITTEL GMBH
Strength100 MCG
Dosage formSOLUTION
Route of administrationNASAL
SchedulePrescription
ATC codeL02AE01 BUSERELIN
AHFS class10:00.00
BiosimilarNo
Health Canada statusCANCELLED POST MARKET
Status date29-Apr-2022
Original market date1998-02-03 00:00:00

How is it stored and handled?

null

How is it supplied?

null

What can be used instead?

Other Canadian products sharing ATC code L02AE01 BUSERELIN. 1 of 7 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.

ProductStrengthFormManufacturerHealth Canada statusDIN
SUPREFACT1 MGSOLUTIONCHEPLAPHARM ARZNEIMITTEL GMBHMARKETEDDIN 02225166
SUPREFACT DEPOT 2 MONTHS6.3 MGIMPLANTCHEPLAPHARM ARZNEIMITTEL GMBHDORMANTDIN 02228955
SUPREFACT DEPOT 3 MONTHS9.45 MGIMPLANTCHEPLAPHARM ARZNEIMITTEL GMBHDORMANTDIN 02240749
SUPREFACT INJ 1MG/ML1 MGLIQUIDHOECHST CANADA INC.CANCELLED POST MARKETDIN 00680028
SUPREFACT INTRANASAL SOLUTION 1MG/ML1 MGSPRAYHOECHST CANADA INC.CANCELLED POST MARKETDIN 00680036
SUPREFACT LIQ 1MG/ML1 MGLIQUIDHOECHST ROUSSEL CANADA INC.CANCELLED POST MARKETDIN 01989669

Who else supplies BUSERELIN worldwide?

Nexara tracks national medicine registries and published price lists across multiple markets. BUSERELIN appears in 10 registered pack listings across 6 markets, published on 5 different national price bases. Where a Canadian route is closed, that is where an alternative route of supply starts — subject to the import rules in both countries.

Registered listings are not stock. Ask us to confirm what can actually be sourced for your order.

Can this still be bought in Canada?

No. This Drug Identification Number is cancelled post market in Health Canada's Drug Product Database, so the product is no longer authorized for sale in Canada and Nexara does not supply it. This page is kept as a regulatory record.

If you are looking for a current equivalent, the alternatives above list every product sharing this therapeutic class, with the marketed ones first. Ask us to source an alternative

Ordering questions

Who can buy this from Nexara?

Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.

Is there a minimum order?

Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.

What is the lead time?

Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.

Can Nexara supply this for a clinical trial?

Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.

Health Canada Drug Product Database (DPD), DIN 02225158. Last reviewed 2026-09-09. Nexara Health is a licensed wholesaler and supplies licensed entities only; consumer orders are routed to a partner pharmacy.