PROCTOSEDYL 1 % — DIN 02223252
FRAMYCETIN SULFATE : 1 % ESCULIN : 1 % DIBUCAINE HYDROCHLORIDE : 0.5 % HYDROCORTISONE : 0.5 % · APTALIS PHARMA CANADA ULC · OINTMENT · wholesale supply in Canada
Health Canada status: CANCELLED POST MARKET
What is PROCTOSEDYL?
PROCTOSEDYL 1 % contains FRAMYCETIN SULFATE : 1 % ESCULIN : 1 % DIBUCAINE HYDROCHLORIDE : 0.5 % HYDROCORTISONE : 0.5 %. It is listed in the Health Canada Drug Product Database under DIN 02223252, held by APTALIS PHARMA CANADA ULC, supplied as OINTMENT for RECTAL administration. Health Canada currently lists it as cancelled post market, status dated 14-May-2024. This Drug Identification Number is no longer authorized for sale in Canada, so Nexara does not supply it. The record is kept here because buyers still meet the number on old formularies, purchase orders and tender documents; Nexara can help identify an authorized alternative.
What is PROCTOSEDYL used for?
The reduction of swelling, pain and inflammation of hemorrhoids and other rectal lesions. The management of acute and chronic nonspecific proctitis, acute internal hemorrhoids, cryptitis, fissures and incomplete fistulas, internal and external pruritus ani. May be used in pre- and postoperative hemorrhoidectomy and repair of fissures. PROCTOSEDYL contains an antibacterial ingredient, framycetin. To reduce the development of drug-resistant bacteria and maintain the effectiveness of framycetin, PROCTOSEDYL should only be used for the authorized indication and clinical use.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
How much does Hydrocortisone cost around the world?
Hydrocortisone is listed on 15 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Australia publishes a ex-manufacturer; Austria publishes a KVP (Kassenverkaufspreis); Bahrain publishes a retail (max). Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| United States | acquisition | 11 | 71 | USD███.██ |
| South Africa | single exit price | 15 | 22 | ZAR███.██ |
| Saudi Arabia | public | 16 | 16 | SAR███.██ |
| Greece | producer price (ex-factory) | 15 | 15 | EUR███.██ |
| Austria | KVP (Kassenverkaufspreis) | 9 | 9 | EUR███.██ |
| Czechia | max producer price (ex-factory) | 5 | 9 | CZK███.██ |
| Australia | ex-manufacturer | 4 | 8 | AUD███.██ |
| United Arab Emirates | public | 4 | 6 | AED███.██ |
| Bahrain | retail (max) | 4 | 6 | BHD███.██ |
| Morocco | PPV (public price) | 5 | 6 | MAD███.██ |
| United Kingdom | hospital | 5 | 5 | GBP███.██ |
| Luxembourg | reimbursement | 4 | 4 | EUR███.██ |
| Iceland | max wholesale | 3 | 3 | ISK███.██ |
| Norway | max AUP (pharmacy retail) | 2 | 2 | NOK███.██ |
| Lebanon | public price (USD, Decision 119/1) | 1 | 1 | USD███.██ |
183 pack listings across 103 brand entries and 14 price bases, refreshed 08 Sep 2026. Ranges span every Hydrocortisone pack in that market, so a high figure is usually a larger pack rather than the same product.
This table is a regulatory record of where the molecule is listed. The DIN on this page is no longer authorized for sale in Canada, so Nexara does not quote it — see the alternatives above.
Is there a generic Hydrocortisone in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
13 holders have a Canadian DIN containing Hydrocortisone, across 32 DINs, of which 10 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| ODAN LABORATORIES LTD | 7 | 6 | ANODAN-HC 10MG SUPPOSITORIES, ANODAN-HC OINTMENT, ODAN PROCTOMYXIN HC, PROCTODAN-HC OINTMENT, PROCTODAN-HC SUPPOSITORIES, +2 more | Sourceable in Canada |
| CHURCH & DWIGHT CANADA CORP | 2 | 2 | ANUSOL-HC OINTMENT, ANUSOL-HC SUPPOSITORIES | Sourceable in Canada |
| TEVA CANADA LIMITED | 4 | 1 | RATIO-HEMCORT-HC, TEVA-PROCTOSONE | Sourceable in Canada |
| JAMP PHARMA CORPORATION | 1 | 1 | JAMPZINC-HC | Sourceable in Canada |
| LABORATOIRE RIVA INC. | 3 | 0 | RECTOGEL HC, RIVA-SOL HC OINTMENT, RIVASOL-HC SUPPOSITORIES | No marketed DIN |
| APTALIS PHARMA CANADA ULC | 2 | 0 | PROCTOSEDYL | No marketed DIN |
| HOECHST ROUSSEL CANADA INC. | 2 | 0 | PROCTOSEDYL OINTMENT, PROCTOSEDYL SUPPOSITORIES | No marketed DIN |
| PHARMASCIENCE INC | 2 | 0 | EGOZINC-HC | No marketed DIN |
| ROUSSEL CANADA INC. | 2 | 0 | PROCTOSEDYL OINTMENT, PROCTOSEDYL SUP | No marketed DIN |
| SANDOZ CANADA INCORPORATED | 2 | 0 | SANDOZ ANUZINC HC, SANDOZ ANUZINC HC PLUS | No marketed DIN |
| TECHNILAB PHARMA INC. | 2 | 0 | PROCTOSONE ONT, PROCTOSONE SUP | No marketed DIN |
| WELCKER-LYSTER LTD., DIVISION OF TECHNILAB INC. | 2 | 0 | RECTOCORT ONT, RECTOCORT SUP | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 1 % |
|---|---|
| Dosage form | OINTMENT |
| Route | RECTAL |
| Pack configuration (monograph) | Ointment, tubes of 15 and 30 g with rectal cannula; suppositories, boxes of 12 and 24. |
| Storage | Store between 15° and 30° C. |
Pack detail is kept as a regulatory record. This DIN is no longer authorized for sale in Canada, so Nexara does not quote this pack.
Substance and classification
| Active substance | Hydrocortisone |
|---|---|
| ATC code | C05AA01 |
| AHFS class | 84:06.00 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02223252 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2223252 |
| Brand name | PROCTOSEDYL |
| Generic / active ingredient | FRAMYCETIN SULFATE : 1 % ESCULIN : 1 % DIBUCAINE HYDROCHLORIDE : 0.5 % HYDROCORTISONE : 0.5 % |
| Market authorization holder | APTALIS PHARMA CANADA ULC |
| Health Canada schedule | Prescription |
| ATC code | C05AA01 |
| ATC anatomical main group | C — Cardiovascular system |
| ATC therapeutic subgroup | C05AA |
| Current status | CANCELLED POST MARKET |
| Status date | 14-May-2024 |
| Original market date | 2003-04-01 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
How is it administered?
Ointment: Apply small quantity morning, evening, and after bowel movements. Suppositories: One suppository morning, evening, and after bowel movements.
Included because it drives pack selection and wastage. Consult the monograph.
Contraindications
Presence of tuberculosis, fungal and viral infections. Sensitivity to any of the components.
Warnings and precautions
Discontinue if sensitization occurs. Complete proctologic exam before use. Prolonged use may produce systemic corticosteroid effects. Misuse may lead to drug-resistant bacteria.
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
10 of 32 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| ANODAN-HC 10MG SUPPOSITORIES | 10 MG | SUPPOSITORY | ODAN LABORATORIES LTD | MARKETED | 02236399 |
| ANODAN-HC OINTMENT | 0.5 % | OINTMENT | ODAN LABORATORIES LTD | MARKETED | 02128446 |
| ANUSOL-HC OINTMENT | 0.5 % | OINTMENT | CHURCH & DWIGHT CANADA CORP | MARKETED | 00505773 |
| ANUSOL-HC SUPPOSITORIES | 10 MG | SUPPOSITORY | CHURCH & DWIGHT CANADA CORP | MARKETED | 00476285 |
| JAMPZINC-HC | 0.5 % | OINTMENT | JAMP PHARMA CORPORATION | MARKETED | 02387239 |
| PROCTODAN-HC OINTMENT | 1 % | OINTMENT | ODAN LABORATORIES LTD | MARKETED | 02234466 |
| PROCTODAN-HC SUPPOSITORIES | 10 MG | SUPPOSITORY | ODAN LABORATORIES LTD | MARKETED | 02240851 |
| PROCTOL OINTMENT | 0.5 % | OINTMENT | ODAN LABORATORIES LTD | MARKETED | 02247322 |
| PROCTOL SUPPOSITORIES | 10 MG | SUPPOSITORY | ODAN LABORATORIES LTD | MARKETED | 02247882 |
| TEVA-PROCTOSONE | 1 % | OINTMENT | TEVA CANADA LIMITED | MARKETED | 02226383 |
2 · Same class — other molecules in ATC C05AA
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Hydrocortisone | ANODAN-HC 10MG SUPPOSITORIES · ANODAN-HC OINTMENT · ANUSOL-HC OINTMENT · ANUSOL-HC SUPPOSITORIES · +23 more | 32 | 10 | Yes |
| Hydrocortisone, Combinations | ANUGESIC-HC OINTMENT · ANUGESIC-HC SUPPOSITORIES · ANUZINC HC · ANUZINC HC PLUS · +1 more | 5 | 0 | Not in Canada |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC C05A
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| C05AD | Anesthetics, Combinations · Benzocaine · Cinchocaine · Lidocaine · Pramocaine · +1 more | 23 | 3 |
| C05AX | Other Agents For Treatment Of Hemorrhoids And Anal Fissures For Topical Use · Other Preparations, Combinations · Zinc Preparations | 20 | 2 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is PROCTOSEDYL called?
The same molecule, Hydrocortisone, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| Alfacort | Latin | Bahrain, Saudi Arabia, United Arab Emirates |
| HYDROCORTISON VUAB | Latin | Czechia |
| Dilucort | Latin | South Africa |
| HYDROCORTISONE LEURQUIN | Latin | Morocco |
| Macleods Hydrocortisone Injection | Latin | South Africa |
| Softacort | Latin | Czechia, Iceland |
| Terracortril | Latin | South Africa |
| Acecort | Latin | Norway |
| CANDICORT CREAM | Latin | Saudi Arabia |
| COLIRCUSI H.C WITH NEOM | Latin | Saudi Arabia |
| CORTIDERM | Latin | Bahrain |
| Cortotic Vet | Latin | Iceland |
| Covocort | Latin | South Africa |
| Daktacort | Latin | South Africa |
| EFFICORT HYDROPHILE | Latin | Morocco |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
Can this still be bought in Canada?
No. This Drug Identification Number is cancelled post market in Health Canada's Drug Product Database, so the product is no longer authorized for sale in Canada and Nexara does not supply it. This page is kept as a regulatory record.
If you are looking for a current equivalent, the alternatives above list every product sharing this therapeutic class, with the marketed ones first. Ask us to source an alternative
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.