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ECRAN TOTAL ANTI-INTOLERANCE SPF 30-CRM 2.5 % — DIN 02159422

TITANIUM DIOXIDE : 2.5 % ENZACAMENE : 5 % TEREPHTHALYLIDENE DICAMPHOR SULFONIC ACID : 3 % AVOBENZONE : 2 % · BIOTHERM CANADA · CREAM · wholesale supply in Canada

Health Canada status: CANCELLED POST MARKET

What is ECRAN TOTAL ANTI-INTOLERANCE SPF 30-CRM?

ECRAN TOTAL ANTI-INTOLERANCE SPF 30-CRM 2.5 % contains TITANIUM DIOXIDE : 2.5 % ENZACAMENE : 5 % TEREPHTHALYLIDENE DICAMPHOR SULFONIC ACID : 3 % AVOBENZONE : 2 %. It is listed in the Health Canada Drug Product Database under DIN 02159422, held by BIOTHERM CANADA, supplied as CREAM for TOPICAL administration. Health Canada currently lists it as cancelled post market, status dated 27-Jul-2001. This Drug Identification Number is no longer authorized for sale in Canada, so Nexara does not supply it. The record is kept here because buyers still meet the number on old formularies, purchase orders and tender documents; Nexara can help identify an authorized alternative.

How much does Combinations Of Protectives Against Uv-Radiation cost around the world?

Combinations Of Protectives Against Uv-Radiation is listed on 4 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.

What a market publishes matters more than the number it publishes. Czechia publishes a max producer price (ex-factory); Hungary publishes a producer price (ex-factory); Iceland publishes a max wholesale. Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.

MarketPrice basis published thereBrandsPacks listedRange
Hungaryproducer price (ex-factory)55HUF███.██
Czechiamax producer price (ex-factory)11CZK███.██
Icelandmax wholesale11ISK███.██
Luxembourgreimbursement11EUR███.██

8 pack listings across 8 brand entries and 4 price bases, refreshed 05 Sep 2026. Ranges span every Combinations Of Protectives Against Uv-Radiation pack in that market, so a high figure is usually a larger pack rather than the same product.

Figures are held for the Nexara team. Cross-market prices are published on incompatible bases and are not an offer, a landed cost, or a guide to what any buyer can obtain. Nexara publishes which markets list the product and on what basis; the numbers stay internal.

Team sign-in

This table is a regulatory record of where the molecule is listed. The DIN on this page is no longer authorized for sale in Canada, so Nexara does not quote it — see the alternatives above.

Is there a generic Combinations Of Protectives Against Uv-Radiation in Canada, and who makes it?

Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.

510 holders have a Canadian DIN containing Combinations Of Protectives Against Uv-Radiation, across 4952 DINs, of which 485 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.

Market authorization holderDINsMarketedBrand namesPosition
EDGEWELL PERSONAL CARE CANADA, ULC12236BANANA BOAT BABY SUNSCREEN LOTION SPF/FPS 60, BANANA BOAT DAILY PROTECT FACE SUNSCREEN LOTION, BANANA BOAT DAILY PROTECT SUNSCREEN LOTION SPF 30, BANANA BOAT DAILY PROTECT SUNSCREEN LOTION SPF 50+, BANANA BOAT DAILY PROTECT SUNSCREEN SPRAY SPF 30, +117 moreSourceable in Canada
FRUIT OF THE EARTH, INC15831BABY MINERAL SUNSCREEN LOTION, BABY SUN PROTECTION LOTION, BABY SUNSCREEN BROAD SPECTRUM SPF 60 LOTION, BLOCK UP OIL FREE 30 SPF, BLOCK-UP OIL FREE 15 SPF, +153 moreSourceable in Canada
BEIERSDORF CANADA INC6929AQUAPHOR LIP REPAIR STICK, COPPERTONE CLEAR BLUE SUNSCREEN, COPPERTONE CLEAR ORANGE SUNSCREEN, COPPERTONE CLEAR SUNSCREEN SPF 30 SPORT, COPPERTONE CLEAR SUNSCREEN SPF 50 SPORT, +64 moreSourceable in Canada
PROCTER & GAMBLE INC110267 IN ONE TONE CORRECTING CC CREAM WITH SPF, AGE DEFYING ANTI-WRINKLE LOTION WITH SPF, AGE DEFYING CLASSIC LOTION WITH SPF, CG SMOOTHERS SPF 15 TINTED MOISTURE, COMPLETE + FACIAL MOISTURIZER WITH SPF BROAD SPECTRUM SPF 40, +102 moreSourceable in Canada
PRIME ENTERPRISES, LLC1142115 CONTINUOUS SPRAY SUNSCREEN WITH INSTANT BRONZER, 15 SPRAY GEL SUNSCREEN WITH INSTANT BRONZER, 30 CONTINUOUS SPRAY SUNSCREEN WITH INSTANT BRONZER, 30 LOTION SUNSCREEN MOISTURE MAX, 30 SPF OIL FREE, +109 moreSourceable in Canada
OMBRELLE CANADA8219AUTOBRONZANT CREME FPS 15, AUTOBRONZANT VAPO FPS 15, BAUME LEVRES ANTI-DESSECHEMENT TRANSPARENT SPF 30, COMPLETE + CARE & PROTECT (80 MINUTES) WATER / SWEAT RESISTANT LOTION SPF 30, COMPLETE + CARE & PROTECT (80 MINUTES) WATER / SWEAT RESISTANT LOTION SPF 50+, +74 moreSourceable in Canada
COOLA LLC3318COOLA CITRUS MIMOSA SCENT SUNSCREEN SPRAY, COOLA CLASSIC BODY SPF 30 SUNSCREEN LOTION TROPICAL COCONUT SCENT, COOLA CLASSIC BODY SPF 50 SUNSCREEN LOTION FRAGRANCE-FREE, COOLA CLASSIC FACE MIST SUNSCREEN, COOLA CLASSIC FACE SPF 30 SUNSCREEN LOTION CUCUMBER SCENT, +28 moreSourceable in Canada
SUN BUM LLC3118CLEAR SUNSCREEN FACE STICK, CONTINUOUS SPRAY SUNSCREEN SUN BUM BROAD SPECTRUM SPF 15, CONTINUOUS SPRAY SUNSCREEN SUN BUM BROAD SPECTRUM SPF 30, CONTINUOUS SPRAY SUNSCREEN SUN BUM BROAD SPECTRUM SPF 50, FACE CREAM 50, +26 moreSourceable in Canada
CLINIQUE LABORATORIES DIST9917ALMOST POWDER MAKEUP TEINT POUDRE NATUREL SPF 18 / FPS 18, CLINIQUE ACNE SOLUTIONS BB CREAM SPF 40 COMBINATION OILY TO OILY, CLINIQUE ADVANCED STOP SIGNS EYE PREVENTIVE CREAM SPF 15, CLINIQUE ADVANCED STOP SIGNS EYE PREVENTIVE CREAM SPF15, CLINIQUE AGE DEFENSE BB CREAM SPF 30, +87 moreSourceable in Canada
KENVUE CANADA INC.1817AVEENO DAILY MOISTURIZING FACE LOTION SPF 30, CLEAR BODY SUNSCREEN SPRAY, DRY-TOUCH SUNSCREEN SPF 45, HYDRO BOOST GEL CREAM SPF 25, HYDRO BOOST HYALURONIC ACID MOISTURIZER SPF 50, +13 moreSourceable in Canada
JOHNSON & JOHNSON INC2411614-DAY SKIN RESCUE SPF 30, ABSOLUTELY AGELESS DAILY MOISTURIZER, ACTIVE BREATHABLE SUNBLOCK SPF 30, ACTIVE BREATHABLE SUNBLOCK SPF 45, ADVANCED SOLUTIONS DAILY MOISTURIZER SPF 15, +227 moreSourceable in Canada
SUPERGOOP, LLC2115DAILY DOSE HYDRATING-CERAMIDE BOOST, DAILYSCREEN, DAILYSCREEN HYDRATING DAILY CREAM, EVERY. SINGLE. FACE. WATERY LOTION, GLOW GLOSS, +16 moreSourceable in Canada

Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.

How is it supplied and stored?

Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.

Strength on the label2.5 %
Dosage formCREAM
RouteTOPICAL

Pack detail is kept as a regulatory record. This DIN is no longer authorized for sale in Canada, so Nexara does not quote this pack.

Substance and classification

Active substanceCombinations Of Protectives Against Uv-Radiation
ATC codeD02BA30
AHFS class84:80.00
Biosimilar biologicNo

Health Canada record and identifiers

The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.

DIN (8-digit, as used in ordering)02159422
DIN (unpadded, as printed on some documents)2159422
Brand nameECRAN TOTAL ANTI-INTOLERANCE SPF 30-CRM
Generic / active ingredientTITANIUM DIOXIDE : 2.5 % ENZACAMENE : 5 % TEREPHTHALYLIDENE DICAMPHOR SULFONIC ACID : 3 % AVOBENZONE : 2 %
Market authorization holderBIOTHERM CANADA
Health Canada scheduleNON-PRESCRIPTION DRUGS
ATC codeD02BA30
ATC anatomical main groupD — Dermatologicals
ATC therapeutic subgroupD02BA
Current statusCANCELLED POST MARKET
Status date27-Jul-2001
Original market date1995-12-31 00:00:00
Status sourceLive Health Canada DPD sync

Verify on the primary sources

Health Canada DPD record

What can be used instead?

Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.

1 · Same molecule, other Canadian presentations

485 of 4952 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.

ProductStrengthFormHolderHealth Canada statusDIN
7 IN ONE TONE CORRECTING CC CREAM WITH SPF3 %CREAMPROCTER & GAMBLE INCMARKETED02514419
ABSOLUTELY AGELESS DAILY MOISTURIZER4 %LOTIONJOHNSON & JOHNSON INCMARKETED02440873
ADAPTASUN SEA AND TROPICS PROTECTIVE BODY LOTION SPF 302.7 %LOTIONNAOS CANADA INC.MARKETED02528029
AGE DEFYING ANTI-WRINKLE LOTION WITH SPF3 %LOTIONPROCTER & GAMBLE INCMARKETED02444208
AGE DEFYING CLASSIC LOTION WITH SPF3 %LOTIONPROCTER & GAMBLE INCMARKETED02460882
ANEW PLATINUM DAY CREAM4.75 %CREAMTHE AVON COMPANY CANADA LIMITEDMARKETED02353873
ANEW ULTIMATE MULTI-PERFORMANCE DAY CREAM CRÈME DE JOUR BROAD SPECTRUM SPF25 À LARGE SPECTRE FPS 254 %CREAMTHE AVON COMPANY CANADA LIMITEDMARKETED02431432
ANTHELIOS 50+10 %LOTIONLABORATOIRES LA ROCHE-POSAY CANADAMARKETED02538938
ANTHELIOS DERMO-KIDS 50+5 %CREAMLABORATOIRES LA ROCHE-POSAY CANADAMARKETED02527766
ANTI-AGING COMPLEX EMULSION BROAD SPECTRUM SPF 302.35 %EMULSIONMERLE NORMAN COSMETICS INCMARKETED02399113

2 · Same class — other molecules in ATC D02BA

MoleculeCanadian brandsDINsMarketedSourceable
Combinations Of Protectives Against Uv-Radiation100 SPF CREAM · 14-DAY SKIN RESCUE SPF 30 · 15 CONTINUOUS SPRAY SUNSCREEN WITH INSTANT BRONZER · 15 SPF FPS PREMIUM SUNSCREEN · +4802 more4952485Yes
Octyl Methoxycinnamate125 FL MOISTURE WHIP LIPSTICK-STK TOP 50MG/G · 25 CREME 410 · 275LW LONG WEARING LIPSTICK 50MG/G · 4-IN-1 LIQUID 14-HOUR WEAR FOUNDATION SPF 15 · +210 more2161Yes
Protectives Against Uv-Radiation For Topical UseA M HAND CREAM SPF 15 · A M INTENSIFIED EMULSION SPF 8 · ADAPTIVE FPS 10 · ALMAY AMAZING LASTING 16 HOUR CONCEALER SPF 6 (SHADES LIGHT AND MEDIUM) · +187 more1971Yes
Aminobenzoic AcidBANANA BOAT DARK TANNING LOTION SPF 4 · BANANA BT.ALOE V.DRY SK.PR.B.LOT W/SS.SPF 4 · BLUE GREEN ALGAE WITH GRAPE SEED EXTRACT MOISTURIZER SPF 10 · BODY SATIN LOTION 4.85% · +10 more140Not in Canada

A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.

3 · Adjacent classes in ATC D02B

ATC subgroupMoleculesDINsMarketed
D02BProtectives Against Uv-Radiation10

Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.

What else is ECRAN TOTAL ANTI-INTOLERANCE SPF 30-CRM called?

The same molecule, Combinations Of Protectives Against Uv-Radiation, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:

NameScriptRegistered in
EkyflogylLatinIceland
OTIPAXLatinCzechia

Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.

Can this still be bought in Canada?

No. This Drug Identification Number is cancelled post market in Health Canada's Drug Product Database, so the product is no longer authorized for sale in Canada and Nexara does not supply it. This page is kept as a regulatory record.

If you are looking for a current equivalent, the alternatives above list every product sharing this therapeutic class, with the marketed ones first. Ask us to source an alternative

Ordering questions

Who can buy this from Nexara?

Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.

Is there a minimum order?

Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.

What is the lead time?

Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.

Why is there no price on this page?

Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.

Can Nexara supply this for a clinical trial?

Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.

Sources and disclaimer

Product data sourced from the Health Canada Drug Product Database. Health Canada status reconciled against the live DPD sync. Last reviewed 10 Sep 2026.

Nothing on this page is medical advice. Nexara Health is a licensed wholesale distributor and supplies licensed entities only; consumer orders are routed to a partner pharmacy. Alternatives tables describe supply, not clinical equivalence.

Health Canada Drug Product Database (DPD), DIN 02159422. Last reviewed 2026-09-10. Nexara Health is a licensed wholesaler and supplies licensed entities only; consumer orders are routed to a partner pharmacy.