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DIFFERIN 0.1 %

ADAPALENE : 0.1 % · DIN 02148749 · GALDERMA CANADA INC

Health Canada status: MARKETED

What is DIFFERIN?

DIFFERIN 0.1 % contains ADAPALENE : 0.1 %. It is listed in the Health Canada Drug Product Database under DIN 02148749, held by GALDERMA CANADA INC, supplied as GEL for TOPICAL administration. Health Canada currently lists it as marketed, status dated 31-Dec-1996. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.

What is DIFFERIN used for?

DIFFERIN (adapalene) topical cream, gel and lotion, and DIFFERIN XP (adapalene) topical gel are indicated for: Treatment of acne vulgaris in patients 12 years of age and older.

Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.

Product details and regulatory record

DIN02148749
Brand nameDIFFERIN
Generic / active ingredientADAPALENE : 0.1 %
ManufacturerGALDERMA CANADA INC
Strength0.1 %
Dosage formGEL
Route of administrationTOPICAL
SchedulePrescription
ATC codeD10AD03 ADAPALENE
AHFS class84:92.00
BiosimilarNo
Health Canada statusMARKETED
Status date31-Dec-1996
Original market date1996-12-31 00:00:00

How is it stored and handled?

null

How is it supplied?

DIFFERIN (adapalene) topical cream, 0.1% w/w: 60 g laminate tube DIFFERIN (adapalene) topical gel, 0.1% w/w: 60 g laminate tube DIFFERIN (adapalene) topical lotion, 0.1% w/w: 60 mL HDPE bottle with pump, 120 mL HDPE bottle with pump DIFFERIN XP (adapalene) topical gel, 0.3% w/w: 60 g laminate tube

What can be used instead?

Other Canadian products sharing ATC code D10AD03 ADAPALENE. 3 of 5 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.

ProductStrengthFormManufacturerHealth Canada statusDIN
DIFFERIN0.1 %CREAMGALDERMA CANADA INCMARKETEDDIN 02231592
DIFFERIN XP0.3 %GELGALDERMA CANADA INCMARKETEDDIN 02274000
DIFFERIN0.1 %LIQUIDGALDERMA CANADA INCCANCELLED POST MARKETDIN 02148757
DIFFERIN0.1 %LOTIONGALDERMA CANADA INCAPPROVEDDIN 02376660

Who else supplies ADAPALENE worldwide?

Nexara tracks national medicine registries and published price lists across multiple markets. ADAPALENE appears in 2012 registered pack listings across 7 markets, published on 6 different national price bases. Where a Canadian route is closed, that is where an alternative route of supply starts — subject to the import rules in both countries.

Registered listings are not stock. Ask us to confirm what can actually be sourced for your order.

How can I get it?

Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.

Request a quote for DIFFERIN

Ordering questions

Who can buy this from Nexara?

Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.

Is there a minimum order?

Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.

What is the lead time?

Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.

Can Nexara supply this for a clinical trial?

Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.

Health Canada Drug Product Database (DPD), DIN 02148749. Last reviewed 2026-09-09. Nexara Health is a licensed wholesaler and supplies licensed entities only; consumer orders are routed to a partner pharmacy.