POTASSIUM PHOSPHATES INJECTION, USP 224 MG

What is POTASSIUM PHOSPHATES INJECTION, USP?

POTASSIUM PHOSPHATES INJECTION, USP 224 MG contains POTASSIUM PHOSPHATE MONOBASIC : 224 MG POTASSIUM PHOSPHATE DIBASIC : 236 MG. It is listed in the Health Canada Drug Product Database under DIN 02139545, held by FRESENIUS KABI CANADA LTD, supplied as SOLUTION for INTRAVENOUS administration. Health Canada currently lists it as marketed, status dated 22-Dec-2015. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.

What is POTASSIUM PHOSPHATES INJECTION, USP used for?

Potassium Phosphates Injection, USP is indicated as a source of phosphate, for addition to large volume intravenous fluids to prevent or correct hypophosphatemia in patients with restricted or no oral intake. It is also useful as an additive for preparing specific intravenous fluid formulas when the needs of the patient cannot be met by standard electrolyte or nutrient solutions.

Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.

Product details and regulatory record

How is it administered?

Potassium Phosphates Injection, USP, is administered intravenously only after dilution in a larger volume of fluid. The dose and rate of administration are dependent upon the individual needs of the patient. Serum potassium, inorganic phosphorus and calcium levels should be monitored as a guide to dosage. Withdraw the calculated volume aseptically and transfer to appropriate intravenous fluid to provide the desired number of millimoles (mmol) of phosphorus and milliequivalents (mEq) of potassium (K+).

Included because it drives pack selection and wastage. Consult the monograph.

How is it stored and handled?

Store at 15 °C to 30 °C.

How is it supplied?

The format 5mL (C860529), 15mL (C860539) and 50mL (C860569) are packaged in Polypropylene plastic clear vials of 20mm of size of 10mL, 20mL and 50mL closed with 20mm gray, chlorobutyl latex free rubber stoppers and sealed with light green aluminum flip cap. The products do not contain a bacteriostatic agent or other preservatives. They are packaged 25 vials per tray. Any unused portion should be discarded. The Potassium Phosphate Injection, USP in the glass vials contains no more than 32,800 mcg/L of aluminum. The Potassium Phosphate Injection, USP in the plastic vials contains no more than 2000 mcg/L of aluminum.

Contraindications

Potassium Phosphates Injection, USP is contraindicated in diseases where high potassium, high phosphate or low calcium levels may be encountered.

Warnings and precautions

Potassium Phosphates Injection, USP must be diluted before use. To avoid potassium or phosphate intoxication, infuse solutions containing potassium phosphates slowly. In patients with severe renal or adrenal insufficiency, administration of potassium phosphates may cause potassium intoxication, infusing high concentrations of phosphate may cause hypocalcemia, and calcium levels should be monitored. This product contains aluminum that may be toxic. Aluminum may reach toxic levels with prolonged parenteral administration if kidney function is impaired. Premature neonates are particularly at risk because their kidneys are immature, and they require large amounts of calcium and phosphate solutions which contain aluminum. Research indicates that patients with impaired kidney function, including premature neonates, who receive parenteral levels of aluminum at greater than 4 to 5 mcg per kg per day accumulate aluminum at levels associated with central nervous system and bone toxicity. Tissue loading may occur at even lower rates of administration of TPN products and of the lock-flush solutions used in their administration.

What can be used instead?

Other Canadian products sharing ATC code B05XA06 POTASSIUM PHOS INCL COMB W/0TH POT. SALTS. 3 of 5 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.

Who else supplies POTASSIUM PHOS INCL COMB W/0TH POT. SALTS worldwide?

Nexara tracks national medicine registries and published price lists across multiple markets. POTASSIUM PHOS INCL COMB W/0TH POT. SALTS appears in 158 registered pack listings across 8 markets, published on 6 different national price bases. Where a Canadian route is closed, that is where an alternative route of supply starts — subject to the import rules in both countries.

Registered listings are not stock. Ask us to confirm what can actually be sourced for your order.