FRAGMIN 10000 UNIT
DALTEPARIN SODIUM : 10000 UNIT · DIN 02132664 · PFIZER CANADA ULC
Health Canada status: CANCELLED POST MARKET
What is FRAGMIN?
FRAGMIN 10000 UNIT contains DALTEPARIN SODIUM : 10000 UNIT. It is listed in the Health Canada Drug Product Database under DIN 02132664, held by PFIZER CANADA ULC, supplied as SOLUTION for INTRAVENOUS ; SUBCUTANEOUS administration. Health Canada currently lists it as cancelled post market, status dated 06-Mar-2024. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is FRAGMIN used for?
Thromboprophylaxis in surgery; treatment of acute deep venous thrombosis; unstable coronary artery disease; prevention of clotting during hemodialysis; extended treatment of VTE in cancer patients.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
Product details and regulatory record
| DIN | 02132664 |
|---|---|
| Brand name | FRAGMIN |
| Generic / active ingredient | DALTEPARIN SODIUM : 10000 UNIT |
| Manufacturer | PFIZER CANADA ULC |
| Strength | 10000 UNIT |
| Dosage form | SOLUTION |
| Route of administration | INTRAVENOUS ; SUBCUTANEOUS |
| Schedule | Prescription |
| ATC code | B01AB04 DALTEPARIN |
| AHFS class | 20:12.04.16 |
| Biosimilar | No |
| Health Canada status | CANCELLED POST MARKET |
| Status date | 06-Mar-2024 |
| Original market date | 1995-12-31 00:00:00 |
How is it administered?
Administered by s.c. injection or i.v. infusion. Dosing varies by indication (e.g., 2500-5000 IU for surgery prophylaxis; 200 IU/kg once daily for DVT treatment). Do not give intramuscularly.
Included because it drives pack selection and wastage. Consult the monograph.
How is it stored and handled?
Store at 15-30°C (implied by standard practice, though specific range text was cut off, the monograph mentions stability for 24h after dilution).
How is it supplied?
3.8 mL multi-dose vials; single-dose prefilled syringes (0.2 mL to 0.72 mL) in packages of 5 or 10.
Contraindications
Hypersensitivity to dalteparin, heparin, or pork products; history of heparin-induced thrombocytopenia; septic endocarditis; active bleeding; major clotting disorders; acute gastroduodenal ulcer.
Warnings and precautions
Risk of spinal/epidural hematoma with neuraxial anesthesia. Multi-dose vial contains benzyl alcohol (fatal 'Gasping Syndrome' risk in neonates). Risk of hemorrhage and thrombocytopenia.
What can be used instead?
Other Canadian products sharing ATC code B01AB04 DALTEPARIN. 10 of 13 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.
| Product | Strength | Form | Manufacturer | Health Canada status | DIN |
|---|---|---|---|---|---|
| FRAGMIN | 10000 UNIT / 0.4 ML | SOLUTION | PFIZER CANADA ULC | MARKETED | DIN 02352656 |
| FRAGMIN | 12500 UNIT / 0.5 ML | SOLUTION | PFIZER CANADA ULC | MARKETED | DIN 02352664 |
| FRAGMIN | 15000 UNIT / 0.6 ML | SOLUTION | PFIZER CANADA ULC | MARKETED | DIN 02352672 |
| FRAGMIN | 16500 UNIT / 0.66 ML | SOLUTION | PFIZER CANADA ULC | MARKETED | DIN 02494582 |
| FRAGMIN | 18000 UNIT / 0.72 ML | SOLUTION | PFIZER CANADA ULC | MARKETED | DIN 02352680 |
| FRAGMIN | 2500 UNIT / 0.2 ML | SOLUTION | PFIZER CANADA ULC | MARKETED | DIN 02132621 |
| FRAGMIN | 25000 UNIT | SOLUTION | PFIZER CANADA ULC | MARKETED | DIN 02231171 |
| FRAGMIN | 3500 UNIT / 0.28 ML | SOLUTION | PFIZER CANADA ULC | MARKETED | DIN 02430789 |
| FRAGMIN | 5000 UNIT / 0.2 ML | SOLUTION | PFIZER CANADA ULC | MARKETED | DIN 02132648 |
| FRAGMIN | 7500 UNIT / 0.3 ML | SOLUTION | PFIZER CANADA ULC | MARKETED | DIN 02352648 |
Who else supplies DALTEPARIN worldwide?
Nexara tracks national medicine registries and published price lists across multiple markets. DALTEPARIN appears in 32 registered pack listings across 4 markets, published on 4 different national price bases. Where a Canadian route is closed, that is where an alternative route of supply starts — subject to the import rules in both countries.
Registered listings are not stock. Ask us to confirm what can actually be sourced for your order.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.