TISSEEL KIT VH 5.0 Strength
Active ingredient(s) See footnote 8 : Strength ANTIHEMOPHILIC FACTOR (HUMAN) : 50 UNIT / ML APROTININ (BOVINE) : 3000 UNIT / ML CALCIUM CHLORIDE : .04 MMOL / ML FIBRINOGEN (HUMAN) : 110 MG / ML PLASMAFIBRONECTIN (CIG) : 9 MG / ML PLASMINOGEN : 120 MCG / ML PROTEIN : 130 MG / ML THROMBIN (BOVINE) : 4 UNIT / ML THROMBIN (BOVINE) : 500 UNIT / ML · DIN 01974327 · OSTERREICHISCHES INSTITUT FUR HAEMODERIVATE GES M.B.H. 67 Industriestrasse Vienna -- Austria 1221
Health Canada status: CANCELLED POST MARKET
What is TISSEEL KIT VH 5.0?
TISSEEL KIT VH 5.0 Strength contains Active ingredient(s) See footnote 8 : Strength ANTIHEMOPHILIC FACTOR (HUMAN) : 50 UNIT / ML APROTININ (BOVINE) : 3000 UNIT / ML CALCIUM CHLORIDE : .04 MMOL / ML FIBRINOGEN (HUMAN) : 110 MG / ML PLASMAFIBRONECTIN (CIG) : 9 MG / ML PLASMINOGEN : 120 MCG / ML PROTEIN : 130 MG / ML THROMBIN (BOVINE) : 4 UNIT / ML THROMBIN (BOVINE) : 500 UNIT / ML. It is listed in the Health Canada Drug Product Database under DIN 01974327, held by OSTERREICHISCHES INSTITUT FUR HAEMODERIVATE GES M.B.H. 67 Industriestrasse Vienna -- Austria 1221, supplied as Powder For Solution for Topical administration. Health Canada currently lists it as cancelled post market, status dated 13-Aug-1998. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What else is TISSEEL KIT VH 5.0 called?
The same molecule, COMBINATIONS, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| Ekyflogyl | Latin | Iceland |
| OTIPAX | Latin | Czechia |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
Product details and regulatory record
| DIN | 01974327 |
|---|---|
| Brand name | TISSEEL KIT VH 5.0 |
| Generic / active ingredient | Active ingredient(s) See footnote 8 : Strength ANTIHEMOPHILIC FACTOR (HUMAN) : 50 UNIT / ML APROTININ (BOVINE) : 3000 UNIT / ML CALCIUM CHLORIDE : .04 MMOL / ML FIBRINOGEN (HUMAN) : 110 MG / ML PLASMAFIBRONECTIN (CIG) : 9 MG / ML PLASMINOGEN : 120 MCG / ML PROTEIN : 130 MG / ML THROMBIN (BOVINE) : 4 UNIT / ML THROMBIN (BOVINE) : 500 UNIT / ML |
| Manufacturer | OSTERREICHISCHES INSTITUT FUR HAEMODERIVATE GES M.B.H. 67 Industriestrasse Vienna -- Austria 1221 |
| Strength | Strength |
| Dosage form | Powder For Solution |
| Route of administration | Topical |
| Schedule | SCHEDULE D , PRESCRIPTION |
| ATC code | B02BD20 COMBINATIONS |
| Biosimilar | No |
| Health Canada status | CANCELLED POST MARKET |
| Status date | 13-Aug-1998 |
| Original market date | 1992-12-31 |
How is this product identified?
Purchase orders, customs paperwork and tender documents each ask for a different identifier, and a DIN written without its leading zeros is the single most common reason an order line fails to match. Every form Nexara accepts for this product is listed here.
| DIN (8-digit, as used in Nexara ordering) | 01974327 |
|---|---|
| DIN (unpadded, as printed on some documents) | 1974327 |
| Brand name | TISSEEL KIT VH 5.0 |
| Active ingredient / INN | Active ingredient(s) See footnote 8 : Strength ANTIHEMOPHILIC FACTOR (HUMAN) : 50 UNIT / ML APROTININ (BOVINE) : 3000 UNIT / ML CALCIUM CHLORIDE : .04 MMOL / ML FIBRINOGEN (HUMAN) : 110 MG / ML PLASMAFIBRONECTIN (CIG) : 9 MG / ML PLASMINOGEN : 120 MCG / ML PROTEIN : 130 MG / ML THROMBIN (BOVINE) : 4 UNIT / ML THROMBIN (BOVINE) : 500 UNIT / ML |
| ATC code | B02BD20 |
| ATC anatomical main group | B — Blood and blood-forming organs |
| ATC therapeutic subgroup | B02 |
| Health Canada schedule | SCHEDULE D , PRESCRIPTION |
| Biosimilar biologic | No |
| Market authorization holder | OSTERREICHISCHES INSTITUT FUR HAEMODERIVATE GES M.B.H. 67 Industriestrasse Vienna -- Austria 1221 |
Which pack is which?
| Strength on the label | Strength |
|---|---|
| Dosage form | Powder For Solution |
| Route | Topical |
One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced. Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
What can be used instead?
Other Canadian products sharing ATC code B02BD20 COMBINATIONS. 0 of 8 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.
| Product | Strength | Form | Manufacturer | Health Canada status | DIN |
|---|---|---|---|---|---|
| TISSEEL KIT VH | 4 UNIT | JELLY | OSTERREICHISCHES INSTITUT FUR HAEMODERIVATE GES M.B.H. | CANCELLED POST MARKET | DIN 00677558 |
| TISSEEL KIT VH 0.5 | 3000 UNIT | POWDER FOR SOLUTION ; LIQUID | OSTERREICHISCHES INSTITUT FUR HAEMODERIVATE GES M.B.H. | CANCELLED POST MARKET | DIN 02017229 |
| TISSEEL KIT VH 1.0 | Strength | Powder For Solution , Liquid | OSTERREICHISCHES INSTITUT FUR HAEMODERIVATE GES M.B.H. 67 Industriestrasse Vienna -- Austria 1221 | CANCELLED POST MARKET | DIN 01949020 |
| TISSEEL KIT VH 1.0 | Strength | Powder For Solution , Kit , Liquid | BAXTER AG Industriestrasse 67 Vienna Saone Et Loire Austria 1220 | CANCELLED POST MARKET | DIN 02233273 |
| TISSEEL KIT VH 2.0 | 100 UNIT / 2 ML | KIT ; POWDER FOR SOLUTION ; LIQUID | BAXTER AG | CANCELLED POST MARKET | DIN 02233274 |
| TISSEEL KIT VH 2.0 | 9 MG | POWDER FOR SOLUTION | OSTERREICHISCHES INSTITUT FUR HAEMODERIVATE GES M.B.H. | CANCELLED POST MARKET | DIN 01949012 |
| TISSEEL KIT VH 5.0 | Strength | Kit , Powder For Solution , Liquid | BAXTER AG Industriestrasse 67 Vienna Saone Et Loire Austria 1220 | CANCELLED POST MARKET | DIN 02233275 |
Who else supplies COMBINATIONS worldwide?
Nexara tracks national medicine registries and published price lists across multiple markets. COMBINATIONS appears in 5 registered pack listings across 2 markets, published on 2 different national price bases. Where a Canadian route is closed, that is where an alternative route of supply starts — subject to the import rules in both countries.
Registered listings are not stock. Ask us to confirm what can actually be sourced for your order.
How much does COMBINATIONS cost around the world?
COMBINATIONS is listed on 4 national price registers Nexara tracks, across 8 pack listings published on 4 different price bases. What each country publishes is set out below.
| Market | What that country publishes | Brands listed | Pack listings | As of |
|---|---|---|---|---|
| Hungary | producer price (ex-factory) | 5 | 5 | 03 Sep 2026 |
| Czechia | max producer price (ex-factory) | 1 | 1 | 03 Sep 2026 |
| Iceland | max wholesale | 1 | 1 | 02 Sep 2026 |
| Luxembourg | reimbursement | 1 | 1 | 05 Sep 2026 |
Why there are no figures here. These bases are not comparable. A Brazilian ex-factory ceiling, a Belgian pharmacy public price and a Japanese reimbursement rate answer three different questions, and none of them is what a product lands in Canada for. Putting them side by side would mislead in both directions, so Nexara publishes where a molecule is listed and on what basis, and quotes the delivered Canadian price per order.
Can this still be bought in Canada?
No. This Drug Identification Number is cancelled post market in Health Canada's Drug Product Database, so the product is no longer authorized for sale in Canada and Nexara does not supply it. This page is kept as a regulatory record.
If you are looking for a current equivalent, the alternatives above list every product sharing this therapeutic class, with the marketed ones first. Ask us to source an alternative
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.