EPINEPHRINE INJECTION USP Strength — DIN 00721891
Active ingredient(s) See footnote 8 : Strength EPINEPHRINE : 1 MG / 1 ML · PFIZER CANADA ULC 17300 Trans-Canada Highway Kirkland Quebec Canada H9J 2M5 · Solution · wholesale supply in Canada
Health Canada status: MARKETED
What is EPINEPHRINE INJECTION USP?
EPINEPHRINE INJECTION USP Strength contains Active ingredient(s) See footnote 8 : Strength EPINEPHRINE : 1 MG / 1 ML. It is listed in the Health Canada Drug Product Database under DIN 00721891, held by PFIZER CANADA ULC 17300 Trans-Canada Highway Kirkland Quebec Canada H9J 2M5, supplied as Solution for Intramuscular , Intravenous , Intracardiac , Intratracheal , Subcutaneous administration. Health Canada currently lists it as marketed, status dated 16-Mar-2018. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is EPINEPHRINE INJECTION USP used for?
In general, the most common uses of parenteral epinephrine are to relieve respiratory distress due to bronchospasm, to provide rapid relief of hypersensitivity (anaphylactic or anaphylactoid) reactions to drugs, animal serums and other allergens, and to prolong the action of infiltration anesthetics. Its cardiac effects may be of use in restoring cardiac rhythm in cardiac arrest due to various causes, and attacks of transitory atrioventricular (A - V) heart block and syncopal seizures (Stokes - Adams syndrome), but it is not used in cardiac failure or in hemorrhagic, traumatic, or cardiogenic shock.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
How much does Epinephrine cost around the world?
Epinephrine is listed on 6 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Bahrain publishes a retail (max); Greece publishes a producer price (ex-factory); Morocco publishes a PPV (public price). Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| United States | acquisition | 3 | 13 | USD███.██ |
| Saudi Arabia | public | 7 | 7 | SAR███.██ |
| Morocco | PPV (public price) | 3 | 6 | MAD███.██ |
| Greece | producer price (ex-factory) | 4 | 4 | EUR███.██ |
| Bahrain | retail (max) | 1 | 1 | BHD███.██ |
| South Africa | single exit price | 1 | 1 | ZAR███.██ |
32 pack listings across 19 brand entries and 6 price bases, refreshed 05 Sep 2026. Ranges span every Epinephrine pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
Is there a generic Epinephrine in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
17 holders have a Canadian DIN containing Epinephrine, across 29 DINs, of which 7 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| MYLAN SPECIALTY LP | 2 | 2 | EPIPEN, EPIPEN JR | Sourceable in Canada |
| HIKMA CANADA LIMITED | 1 | 1 | EPINEPHRINE INJECTION USP | Sourceable in Canada |
| LABORATOIRE AGUETTANT | 1 | 1 | EPINEPHRINE INJECTION | Sourceable in Canada |
| PFIZER CANADA ULC | 1 | 1 | EPINEPHRINE INJECTION USP | Sourceable in Canada |
| PFIZER CANADA ULC 17300 Trans-Canada Highway Kirkland Quebec Canada H9J 2M5 | 1 | 1 | EPINEPHRINE INJECTION USP | Sourceable in Canada |
| SEARCHLIGHT PHARMA INC | 1 | 1 | ADRENALIN | Sourceable in Canada |
| AMEDRA PHARMACEUTICALS LLC | 4 | 0 | ADRENACLICK 0.15MG AUTO-INJECTOR, ADRENACLICK 0.30MG AUTO-INJECTOR, TWINJECT 0.15MG AUTO-INJECTOR, TWINJECT 0.3MG AUTO-INJECTOR | No marketed DIN |
| TARO PHARMACEUTICALS INC | 4 | 0 | TARO-EPINEPHRINE AUTO-INJECTOR, TAROCLICK EPINEPHRINE, TAROCLICK EPINEPHRINE JUNIOR | No marketed DIN |
| BAUSCH HEALTH, CANADA INC. | 3 | 0 | EMERADE | No marketed DIN |
| ENDO OPERATIONS LTD. | 2 | 0 | ANAPEN, ANAPEN JUNIOR | No marketed DIN |
| INTERNATIONAL MEDICATION SYSTEMS LTD. | 2 | 0 | EPINEPHRINE 1:1000 INJ 1MG/ML USP, EPINEPHRINE INJ 1:10000 STERILE | No marketed DIN |
| VALEO PHARMA INC | 2 | 0 | ALLERJECT | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | Strength |
|---|---|
| Dosage form | Solution |
| Route | Intramuscular , Intravenous , Intracardiac , Intratracheal , Subcutaneous |
| Pack configuration (monograph) | Ampoule 1 mL, Abboject® Syringe 10 mL (Adult or Pediatric), LifeShield® Abboject® Syringe 10 mL (Adult or Pediatric) |
| Storage | Store between 20 and 25°C. Protect from light, freezing and excessive heat. |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Epinephrine |
|---|---|
| ATC code | C01CA24 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 00721891 |
|---|---|
| DIN (unpadded, as printed on some documents) | 721891 |
| Brand name | EPINEPHRINE INJECTION USP |
| Generic / active ingredient | Active ingredient(s) See footnote 8 : Strength EPINEPHRINE : 1 MG / 1 ML |
| Market authorization holder | PFIZER CANADA ULC 17300 Trans-Canada Highway Kirkland Quebec Canada H9J 2M5 |
| Health Canada schedule | ETHICAL |
| ATC code | C01CA24 |
| ATC anatomical main group | C — Cardiovascular system |
| ATC therapeutic subgroup | C01CA |
| Current status | MARKETED |
| Status date | 16-Mar-2018 |
| Original market date | 1988-12-31 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
Is Epinephrine in shortage in Canada?
A Canadian shortage report is on file for a product containing this molecule: Active — reported by PFIZER CANADA ULC, last seen 09 Sep 2026. A shortage on one presentation does not always affect every DIN of the molecule — the alternatives below list what else is marketed in Canada. Nexara can confirm current availability and identify substitutions or import options where permitted.
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
7 of 29 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| ADRENALIN | 1 MG | SOLUTION | SEARCHLIGHT PHARMA INC | MARKETED | 00155357 |
| EPINEPHRINE INJECTION | 1 MG / 10 ML | SOLUTION | LABORATOIRE AGUETTANT | MARKETED | 02521148 |
| EPINEPHRINE INJECTION USP | 1 MG / 10 ML | SOLUTION | PFIZER CANADA ULC | MARKETED | 00710814 |
| EPINEPHRINE INJECTION USP | 1 MG / 1 ML | SOLUTION | HIKMA CANADA LIMITED | MARKETED | 02435810 |
| EPIPEN | 0.3 MG / 0.3 ML | SOLUTION | MYLAN SPECIALTY LP | MARKETED | 00509558 |
| EPIPEN JR | 0.15 MG / 0.3 ML | SOLUTION | MYLAN SPECIALTY LP | MARKETED | 00578657 |
| ADRENACLICK 0.15MG AUTO-INJECTOR | 0.15 MG / 0.15 ML | SOLUTION | AMEDRA PHARMACEUTICALS LLC | CANCELLED PRE MARKET | 02354322 |
| ADRENACLICK 0.30MG AUTO-INJECTOR | 0.30 MG / 0.30 ML | SOLUTION | AMEDRA PHARMACEUTICALS LLC | CANCELLED PRE MARKET | 02354330 |
| ALLERJECT | 0.15 MG / 0.15 ML | SOLUTION | VALEO PHARMA INC | CANCELLED POST MARKET | 02382059 |
| ALLERJECT | 0.3 MG / 0.3 ML | SOLUTION | VALEO PHARMA INC | CANCELLED POST MARKET | 02382067 |
2 · Same class — other molecules in ATC C01CA
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Midodrine | AMATINE · APO-MIDODRINE · JAMP MIDODRINE · M-MIDODRINE · +2 more | 12 | 10 | Yes |
| Epinephrine | ADRENACLICK 0.15MG AUTO-INJECTOR · ADRENACLICK 0.30MG AUTO-INJECTOR · ADRENALIN · ALLERJECT · +17 more | 29 | 7 | Yes |
| Phenylephrine | NEO-SYNEPHRINE · NEO-SYNEPHRINE INJ LIQ 10MG/ML · NEO-SYNEPHRINE LIQ 1% · PHENYLEPHRINE HYDROCHLORIDE INJECTION · +4 more | 15 | 5 | Yes |
| Norepinephrine | LEVOPHED · LEVOPHED LIQ IV 1.0MG/ML · NOREPINEPHRINE BITARTRATE IN 5% DEXTROSE INJECTION · NOREPINEPHRINE BITARTRATE INJECTION · +2 more | 10 | 5 | Yes |
| Dopamine | DOPAMINE HCL 0.8MG/ML DEXTROSE 5% INJ USP · DOPAMINE HCL 1.6MG/ML DEXTROSE 5% INJ USP · DOPAMINE HCL 3.2MG/ML DEXTROSE 5% INJ USP · DOPAMINE HCL INJ 4% · +2 more | 8 | 3 | Yes |
| Isoprenaline | ISOPROTERENOL HCL INJ 1:5000 · ISOPROTERENOL HYDROCHLORIDE INJECTION USP · ISUPREL INJ 0.2MG/ML · ISUPREL LIQ 0.2MG/ML | 7 | 3 | Yes |
| Dobutamine | DOBUTAMINE 12.5MG/ML · DOBUTAMINE HYDROCHLORIDE INJECTION-12.5MG/ML · DOBUTAMINE INJECTION SDZ · DOBUTAMINE INJECTION USP · +1 more | 9 | 2 | Yes |
| Ephedrine | EPHEDRINE SULFATE INJECTION USP · EPHEDRINE SULFATE INJECTION USP, 50MG/ML · EPHEDRINE SULFATE INJECTION, USP · EPHEDRINE SULPHATE INJECTION, USP | 6 | 1 | Yes |
| Epinephrine, Combinations | ANA-KIT · ANA-KIT (2MG/TAB ORL, 1MG/ML LIQ SC IM) · ANAKIT INSECT STING TREATMENT KIT | 3 | 0 | Not in Canada |
| Mephentermine | WYAMINE SULFATE INJECTION LIQ 30MG/ML | 1 | 0 | Not in Canada |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC C01C
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| C01CE | Amrinone · Milrinone | 12 | 2 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.