OTRIVIN MEDICATED COLD & ALLERGY RELIEF 0.1 % — DIN 00653330
XYLOMETAZOLINE HYDROCHLORIDE : 0.1 % · HALEON CANADA ULC · SPRAY · wholesale supply in Canada
Health Canada status: MARKETED
What is OTRIVIN MEDICATED COLD & ALLERGY RELIEF?
OTRIVIN MEDICATED COLD & ALLERGY RELIEF 0.1 % contains XYLOMETAZOLINE HYDROCHLORIDE : 0.1 %. It is listed in the Health Canada Drug Product Database under DIN 00653330, held by HALEON CANADA ULC, supplied as SPRAY for NASAL administration. Health Canada currently lists it as marketed, status dated 08-Jun-2026. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
How much does Xylometazoline cost around the world?
Xylometazoline is listed on 2 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Morocco publishes a PPV (public price); South Africa publishes a single exit price. Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| South Africa | single exit price | 6 | 6 | ZAR███.██ |
| Morocco | PPV (public price) | 1 | 2 | MAD███.██ |
8 pack listings across 7 brand entries and 2 price bases, refreshed 05 Sep 2026. Ranges span every Xylometazoline pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
Is there a generic Xylometazoline in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
13 holders have a Canadian DIN containing Xylometazoline, across 31 DINs, of which 5 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| HALEON CANADA ULC | 3 | 3 | OTRIVIN MEDICATED COLD & ALLERGY RELIEF, OTRIVIN MEDICATED COLD & ALLERGY RELIEF WITH MOISTURIZERS, OTRIVIN MEDICATED COMPLETE NASAL CARE | Sourceable in Canada |
| CRLS | 2 | 2 | DECONGESTANT NASAL SPRAY, NASAL DECONGESTANT SPRAY WITH MOISTURIZERS | Sourceable in Canada |
| NOVARTIS CONSUMER HEALTH CANADA INC. | 5 | 0 | OTRIVIN DECONGESTANT NOSE DROPS 0.05%, OTRIVIN MENTHOL - ASP-LIQ 0.1%, OTRIVIN PEDIATRIC DECONGESTANT NOSE DROPS, OTRIVIN PEDIATRIC NASAL SPRAY 0.05%, OTRIVIN WITH M-D PUMP | No marketed DIN |
| TEVA CANADA LIMITED | 5 | 0 | BALMINIL DECONGEST, BALMINIL NASAL DECONGESTANT, COLD AND ALLERGY DECONGESTANT NASAL SPRAY, DECONGEST NASAL, DECONGESTANT NASAL SPRAY 0.1% | No marketed DIN |
| GLAXOSMITHKLINE CONSUMER HEALTHCARE ULC | 3 | 0 | OTRIVIN ALLERGY AND COLD DECONGESTANT NASAL SPRAY, OTRIVIN COLD AND ALLERGY DECONGESTANT NOSE DROPS, OTRIVIN SINUS RELIEF | No marketed DIN |
| LABORATOIRES CONFAB INC | 3 | 0 | DECONGESTANT NOSE DROPS 0.1%, NASAL DECONGESTANT SPRAY WITH MOISTURIZERS, VAPORISATEUR NASAL DECONGESTIONNANT | No marketed DIN |
| JAMP PHARMA CORPORATION | 2 | 0 | DECONGESTANT NASAL SPRAY, DECONGESTANT NASAL SPRAY WITH MOISTURIZERS | No marketed DIN |
| PHARMASCIENCE INC | 2 | 0 | COLD & ALLERGY RELIEF, COLD & ALLERGY RELIEF WITH MOISTURIZERS | No marketed DIN |
| PRODEMDIS ENR. | 2 | 0 | CERTIFIED DECONGESTANT NASAL SPRAY .1%, DECONGESTANT NASAL SPRAY 0.1% | No marketed DIN |
| KSL PHARMACEUTICALS | 1 | 0 | DECONGESTANT NASAL SPRAY 0.1% USP | No marketed DIN |
| STANLEY PHARMACEUTICALS, A DIVISION OF VITA HEALTH PRODUCTS INC. | 1 | 0 | DECONGESTANT NASAL SPRAY 0.1% W/V | No marketed DIN |
| WES PAK PRODUCTS LTD. | 1 | 0 | DECONGESTANT NASAL SPRAY - 0.10% | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 0.1 % |
|---|---|
| Dosage form | SPRAY |
| Route | NASAL |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Xylometazoline |
|---|---|
| ATC code | R01AA07 |
| AHFS class | 52:32.00 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 00653330 |
|---|---|
| DIN (unpadded, as printed on some documents) | 653330 |
| Brand name | OTRIVIN MEDICATED COLD & ALLERGY RELIEF |
| Generic / active ingredient | XYLOMETAZOLINE HYDROCHLORIDE : 0.1 % |
| Market authorization holder | HALEON CANADA ULC |
| Health Canada schedule | NON-PRESCRIPTION DRUGS |
| ATC code | R01AA07 |
| ATC anatomical main group | R — Respiratory system |
| ATC therapeutic subgroup | R01AA |
| Current status | MARKETED |
| Status date | 08-Jun-2026 |
| Original market date | 1961-12-31 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
5 of 31 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| DECONGESTANT NASAL SPRAY | 0.1 % | SPRAY | CRLS | MARKETED | 02452812 |
| NASAL DECONGESTANT SPRAY WITH MOISTURIZERS | 0.1 % | SPRAY | CRLS | MARKETED | 02452863 |
| OTRIVIN MEDICATED COLD & ALLERGY RELIEF WITH MOISTURIZERS | 0.1 % | SPRAY | HALEON CANADA ULC | MARKETED | 02208903 |
| OTRIVIN MEDICATED COMPLETE NASAL CARE | 0.1 % | SPRAY | HALEON CANADA ULC | MARKETED | 02331403 |
| BALMINIL DECONGEST | 0.1 % | SOLUTION | TEVA CANADA LIMITED | CANCELLED POST MARKET | 02300257 |
| BALMINIL NASAL DECONGESTANT | 0.1 % | SPRAY | TEVA CANADA LIMITED | DORMANT | 00791172 |
| CERTIFIED DECONGESTANT NASAL SPRAY .1% | 0.1 % | SPRAY ; SOLUTION | PRODEMDIS ENR. | CANCELLED POST MARKET | 02054701 |
| COLD & ALLERGY RELIEF | 0.1 % | SPRAY | PHARMASCIENCE INC | CANCELLED POST MARKET | 02246021 |
| COLD & ALLERGY RELIEF WITH MOISTURIZERS | 0.1 % | SPRAY | PHARMASCIENCE INC | CANCELLED POST MARKET | 02246023 |
| COLD AND ALLERGY DECONGESTANT NASAL SPRAY | 0.1 % | SPRAY | TEVA CANADA LIMITED | CANCELLED POST MARKET | 02351927 |
2 · Same class — other molecules in ATC R01AA
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Oxymetazoline | AESB - OXYMETAZOLINE HYDROCHLORIDE NASAL SOLUTION USP, 0.025% · AFRIN COLD · CLARITIN ALLERGY DECONGESTANT · COOLING MENTHOL NASAL SPRAY · +34 more | 42 | 13 | Yes |
| Xylometazoline | BALMINIL DECONGEST · BALMINIL NASAL DECONGESTANT · CERTIFIED DECONGESTANT NASAL SPRAY .1% · COLD & ALLERGY RELIEF · +24 more | 31 | 5 | Yes |
| Phenylephrine | NEO SYNEPHRINE NASAL DROP 1% · NEO-SYNEPHRINE NASAL DROP 1% | 2 | 0 | Not in Canada |
| Ephedrine | FORMULE G8 LIQ 1.5% | 1 | 0 | Not in Canada |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC R01A
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| R01AD | Beclomethasone · Budesonide · Ciclesonide · Flunisolide · Fluticasone · +5 more | 55 | 24 |
| R01AX | Combinations · Ipratropium Bromide · Various | 42 | 4 |
| R01AB | Ephedrine · Naphazoline · Oxymetazoline · Phenylephrine | 12 | 1 |
| R01AC | Cromoglicic Acid · Levocabastine | 6 | 0 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What else is OTRIVIN MEDICATED COLD & ALLERGY RELIEF called?
The same molecule, Xylometazoline, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:
| Name | Script | Registered in |
|---|---|---|
| OTRIVINE | Latin | Morocco |
| Otrivin Adult Drops | Latin | South Africa |
| Otrivin Adult Spray | Latin | South Africa |
| Otrivin Menthol Adult | Latin | South Africa |
| Otrivin Paed Drops | Latin | South Africa |
| Otrivin Paed Spray | Latin | South Africa |
| Zylovin | Latin | South Africa |
Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.