ZANOSAR STERILE POWDER 1 G
STREPTOZOCIN : 1 G · DIN 00622141 · PALADIN PHARMA INC.
Health Canada status: CANCELLED POST MARKET
What is ZANOSAR STERILE POWDER?
ZANOSAR STERILE POWDER 1 G contains STREPTOZOCIN : 1 G. It is listed in the Health Canada Drug Product Database under DIN 00622141, held by PALADIN PHARMA INC., supplied as POWDER FOR SOLUTION for INTRAVENOUS administration. Health Canada currently lists it as cancelled post market, status dated 19-Dec-2017. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is ZANOSAR STERILE POWDER used for?
Treatment of metastatic islet cell carcinoma of the pancreas (functional and non-functional). Limited to symptomatic or progressive metastatic disease due to renal toxicity.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
Product details and regulatory record
| DIN | 00622141 |
|---|---|
| Brand name | ZANOSAR STERILE POWDER |
| Generic / active ingredient | STREPTOZOCIN : 1 G |
| Manufacturer | PALADIN PHARMA INC. |
| Strength | 1 G |
| Dosage form | POWDER FOR SOLUTION |
| Route of administration | INTRAVENOUS |
| Schedule | Prescription |
| ATC code | L01AD04 STREPTOZOCIN |
| AHFS class | 10:00.00 |
| Biosimilar | No |
| Health Canada status | CANCELLED POST MARKET |
| Status date | 19-Dec-2017 |
| Original market date | 1985-12-31 00:00:00 |
How is it administered?
IV only. Daily: 500 mg/m2 for 5 days every 6 weeks. Weekly: 1000 mg/m2 weekly for 2 weeks; may escalate but not to exceed 1500 mg/m2 per single dose.
Included because it drives pack selection and wastage. Consult the monograph.
How is it stored and handled?
Unopened: Refrigerate (2-8°C) and protect from light. Reconstituted: Stable for 48h refrigerated or 24h at room temp; use within 12h recommended.
How is it supplied?
Supplied as 1 g vials containing an off-white to pale yellow freeze-dried cake.
Contraindications
Known hypersensitivity to streptozocin. Pre-existing renal disease is a strong contraindication.
Warnings and precautions
Renal toxicity may be fatal; monitor renal function before, during, and after therapy. Avoid extravasation (necrosis). Mutagenic and carcinogenic. Avoid live vaccines.
Who else supplies STREPTOZOCIN worldwide?
Nexara tracks national medicine registries and published price lists across multiple markets. STREPTOZOCIN appears in 2 registered pack listings across 2 markets, published on 2 different national price bases. Where a Canadian route is closed, that is where an alternative route of supply starts — subject to the import rules in both countries.
Registered listings are not stock. Ask us to confirm what can actually be sourced for your order.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.