DENTSPLY 4% PRILOCAINE AND EPINEPHRINE INJECTION 1:200,000 5 MCG
EPINEPHRINE (EPINEPHRINE BITARTRATE) : 5 MCG PRILOCAINE HYDROCHLORIDE : 40 MG · DIN 00519227 · DENTSPLY CANADA LIMITED
Health Canada status: CANCELLED POST MARKET
What is DENTSPLY 4% PRILOCAINE AND EPINEPHRINE INJECTION 1:200,000?
DENTSPLY 4% PRILOCAINE AND EPINEPHRINE INJECTION 1:200,000 5 MCG contains EPINEPHRINE (EPINEPHRINE BITARTRATE) : 5 MCG PRILOCAINE HYDROCHLORIDE : 40 MG. It is listed in the Health Canada Drug Product Database under DIN 00519227, held by DENTSPLY CANADA LIMITED, supplied as SOLUTION for BLOCK/INFILTRATION administration. Health Canada currently lists it as cancelled post market, status dated 19-Jul-2012. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is DENTSPLY 4% PRILOCAINE AND EPINEPHRINE INJECTION 1:200,000 used for?
Indicated in dentistry for the production of local anesthesia by infiltration or nerve block.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
Product details and regulatory record
| DIN | 00519227 |
|---|---|
| Brand name | DENTSPLY 4% PRILOCAINE AND EPINEPHRINE INJECTION 1:200,000 |
| Generic / active ingredient | EPINEPHRINE (EPINEPHRINE BITARTRATE) : 5 MCG PRILOCAINE HYDROCHLORIDE : 40 MG |
| Manufacturer | DENTSPLY CANADA LIMITED |
| Strength | 5 MCG |
| Dosage form | SOLUTION |
| Route of administration | BLOCK/INFILTRATION |
| Schedule | Ethical |
| ATC code | N01BB54 PRILOCAINE, COMBINATIONS |
| AHFS class | 72:00.00 |
| Biosimilar | No |
| Health Canada status | CANCELLED POST MARKET |
| Status date | 19-Jul-2012 |
| Original market date | 1968-12-31 00:00:00 |
How is it administered?
Adults: 1-2 mL (40-80 mg) usually adequate; max 400 mg (10 mL) per procedure. Children <10 years: rarely more than 0.9-1 mL (36-40 mg). Inject slowly with frequent aspiration.
Included because it drives pack selection and wastage. Consult the monograph.
How is it stored and handled?
Cartridges should not be autoclaved. Avoid immersion in disinfectants. Store appropriately to protect from light and metal contact.
How is it supplied?
Dental cartridges (glass) for use with a syringe.
Contraindications
Known hypersensitivity to amide-type local anesthetics; congenital or idiopathic methemoglobinemia.
Warnings and precautions
Risk of dose-related toxicity and methemoglobinemia. Avoid intravascular injection. Epinephrine formulation contains sodium metabisulfite (allergic risk). Monitor CNS and cardiovascular signs.
What can be used instead?
Other Canadian products sharing ATC code N01BB54 PRILOCAINE, COMBINATIONS. 4 of 5 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.
| Product | Strength | Form | Manufacturer | Health Canada status | DIN |
|---|---|---|---|---|---|
| 4% CITANEST FORTE DENTAL WITH EPINEPHRINE 1:200,000 | 0.005 MG | SOLUTION | DENTSPLY CANADA LIMITED | MARKETED | DIN 02347695 |
| EMLA CREAM | 2.5 % | CREAM | ASPEN PHARMACARE CANADA INC. | MARKETED | DIN 00886858 |
| EMLA PATCH | 2.5 % | PATCH | ASPEN PHARMACARE CANADA INC. | MARKETED | DIN 02057794 |
| PRILOCAINE HCL 4% EPINEPH 1:200000INJ | 40 MG | SOLUTION | NOVOCOL PHARMACEUTICAL OF CANADA INC | MARKETED | DIN 00393746 |
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Request a quote for DENTSPLY 4% PRILOCAINE AND EPINEPHRINE INJECTION 1:200,000
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.