AMINOSYN 440 MG / 100 ML
L-PHENYLALANINE : 440 MG / 100 ML L-THREONINE : 520 MG / 100 ML L-LYSINE (L-LYSINE ACETATE) : 720 MG / 100 ML L-ALANINE : 1280 MG / 100 ML L-LEUCINE : 940 MG / 100 ML L-ARGININE : 980 MG / 100 ML SERINE : 420 MG / 100 ML L-TYROSINE : 44 MG / 100 ML L-VALINE : 800 MG / 100 ML L-PROLINE : 860 MG / 100 ML TRYPTOPHAN : 160 MG / 100 ML HISTIDINE : 300 MG / 100 ML METHIONINE : 400 MG / 100 ML L-ISOLEUCINE : 720 MG / 100 ML GLYCINE : 1280 MG / 100 ML · DIN 00454907 · ICU MEDICAL CANADA INC
Health Canada status: CANCELLED POST MARKET
What is AMINOSYN?
AMINOSYN 440 MG / 100 ML contains L-PHENYLALANINE : 440 MG / 100 ML L-THREONINE : 520 MG / 100 ML L-LYSINE (L-LYSINE ACETATE) : 720 MG / 100 ML L-ALANINE : 1280 MG / 100 ML L-LEUCINE : 940 MG / 100 ML L-ARGININE : 980 MG / 100 ML SERINE : 420 MG / 100 ML L-TYROSINE : 44 MG / 100 ML L-VALINE : 800 MG / 100 ML L-PROLINE : 860 MG / 100 ML TRYPTOPHAN : 160 MG / 100 ML HISTIDINE : 300 MG / 100 ML METHIONINE : 400 MG / 100 ML L-ISOLEUCINE : 720 MG / 100 ML GLYCINE : 1280 MG / 100 ML. It is listed in the Health Canada Drug Product Database under DIN 00454907, held by ICU MEDICAL CANADA INC, supplied as SOLUTION for INTRAVENOUS administration. Health Canada currently lists it as cancelled post market, status dated 24-Jan-2019. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is AMINOSYN used for?
Source of nitrogen for acute surgical patients (peripheral); adjunct in prevention of nitrogen loss or treatment of negative nitrogen balance (central) when oral/enteral nutrition is not feasible.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
Product details and regulatory record
| DIN | 00454907 |
|---|---|
| Brand name | AMINOSYN |
| Generic / active ingredient | L-PHENYLALANINE : 440 MG / 100 ML L-THREONINE : 520 MG / 100 ML L-LYSINE (L-LYSINE ACETATE) : 720 MG / 100 ML L-ALANINE : 1280 MG / 100 ML L-LEUCINE : 940 MG / 100 ML L-ARGININE : 980 MG / 100 ML SERINE : 420 MG / 100 ML L-TYROSINE : 44 MG / 100 ML L-VALINE : 800 MG / 100 ML L-PROLINE : 860 MG / 100 ML TRYPTOPHAN : 160 MG / 100 ML HISTIDINE : 300 MG / 100 ML METHIONINE : 400 MG / 100 ML L-ISOLEUCINE : 720 MG / 100 ML GLYCINE : 1280 MG / 100 ML |
| Manufacturer | ICU MEDICAL CANADA INC |
| Strength | 440 MG / 100 ML |
| Dosage form | SOLUTION |
| Route of administration | INTRAVENOUS |
| Schedule | Ethical |
| ATC code | B05BA01 AMINO ACIDS |
| AHFS class | 40:20.00 |
| Biosimilar | No |
| Health Canada status | CANCELLED POST MARKET |
| Status date | 24-Jan-2019 |
| Original market date | 1979-12-31 00:00:00 |
How is it administered?
Individualized based on protein requirements. Peripheral: max 1.5 g/kg/day amino acids (must be diluted). Central: often 3.5% amino acid with 20-25% dextrose. Max 24h infusion per container.
Included because it drives pack selection and wastage. Consult the monograph.
How is it stored and handled?
Store between 20° and 25°C. Do not freeze. Protect from light. Avoid excessive heat. Use promptly after mixing (refrigerate < 24h).
How is it supplied?
500 mL and 1000 mL flexible plastic containers.
Contraindications
Hypersensitivity to product/components; hepatic coma; anuria; metabolic disorders involving impaired nitrogen utilization; azotemia.
Warnings and precautions
May rise BUN; aluminum toxicity risk in renal impairment/neonates; hyperammonemia risk (especially infants); central vein administration requires specialized expertise; monitor electrolytes/glucose.
What can be used instead?
Other Canadian products sharing ATC code B05BA01 AMINO ACIDS. 4 of 26 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.
| Product | Strength | Form | Manufacturer | Health Canada status | DIN |
|---|---|---|---|---|---|
| 20% PROSOL | 1.18 G / 100 ML | LIQUID | BAXTER CORPORATION | MARKETED | DIN 02141450 |
| ESSEPNA | 1.1 G / 100 ML | SOLUTION | FRESENIUS KABI CANADA LTD | MARKETED | DIN 02510324 |
| PRIMENE 10% | 189 MG / 100 ML | LIQUID | BAXTER CORPORATION | MARKETED | DIN 02236875 |
| TRAVASOL | 600 MG / 100 ML | SOLUTION | BAXTER CORPORATION | MARKETED | DIN 00872296 |
| 4.25% AMINO ACID INJECTION WITHOUT ELECTROLYTES IN 20% DEXTROSE QUICKMIX | 76 MG / 100 ML | SOLUTION | BAXTER CORPORATION CLINTEC NUTRITION DIVISION | CANCELLED POST MARKET | DIN 02013908 |
| 8.5% FREAMINE III | 770 MG / 100 ML | LIQUID | B. BRAUN MEDICAL INC | CANCELLED POST MARKET | DIN 02158647 |
| AMINOSYN 5% | 220 MG / 100 ML | SOLUTION | HOSPIRA HEALTHCARE ULC | CANCELLED POST MARKET | DIN 00404160 |
| AMINOSYN 7% | 690 MG / 100 ML | SOLUTION | HOSPIRA HEALTHCARE ULC | CANCELLED POST MARKET | DIN 00523232 |
| AMINOSYN 8.5% | 624 MG / 100 ML | SOLUTION | HOSPIRA HEALTHCARE ULC | CANCELLED POST MARKET | DIN 00613320 |
| AMINOSYN II | 172 MG / 100 ML | SOLUTION | ICU MEDICAL CANADA INC | DORMANT | DIN 00742619 |
Who else supplies AMINO ACIDS worldwide?
Nexara tracks national medicine registries and published price lists across multiple markets. AMINO ACIDS appears in 215 registered pack listings across 5 markets, published on 4 different national price bases. Where a Canadian route is closed, that is where an alternative route of supply starts — subject to the import rules in both countries.
Registered listings are not stock. Ask us to confirm what can actually be sourced for your order.
Can this still be bought in Canada?
No. This Drug Identification Number is cancelled post market in Health Canada's Drug Product Database, so the product is no longer authorized for sale in Canada and Nexara does not supply it. This page is kept as a regulatory record.
If you are looking for a current equivalent, the alternatives above list every product sharing this therapeutic class, with the marketed ones first. Ask us to source an alternative
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.