ISOTAMINE B 300 15 MG — DIN 00236799
PYRIDOXINE HYDROCHLORIDE : 15 MG ISONIAZID : 300 MG · BAUSCH HEALTH, CANADA INC. · TABLET · wholesale supply in Canada
Health Canada status: DORMANT
What is ISOTAMINE B 300?
ISOTAMINE B 300 15 MG contains PYRIDOXINE HYDROCHLORIDE : 15 MG ISONIAZID : 300 MG. It is listed in the Health Canada Drug Product Database under DIN 00236799, held by BAUSCH HEALTH, CANADA INC., supplied as TABLET for ORAL administration. Health Canada currently lists it as dormant, status dated 09-Dec-2020. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A). This DIN is not currently being marketed in Canada, so it is sourced to order where a compliant route exists rather than held in stock.
What is ISOTAMINE B 300 used for?
Treatment of clinical tuberculosis (with other agents) and prevention of tuberculosis in high-risk individuals or close contacts.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 15 MG |
|---|---|
| Dosage form | TABLET |
| Route | ORAL |
| Pack configuration (monograph) | Bottles of 100 and 1000 tablets. |
| Storage | Store in well-closed, light-resistant containers at controlled room temperature (15 – 30 ºC). Protect from light, air, and excessive heat. |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Isoniazid, Combinations |
|---|---|
| ATC code | J04AC51 |
| AHFS class | 08:16.04 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 00236799 |
|---|---|
| DIN (unpadded, as printed on some documents) | 236799 |
| Brand name | ISOTAMINE B 300 |
| Generic / active ingredient | PYRIDOXINE HYDROCHLORIDE : 15 MG ISONIAZID : 300 MG |
| Market authorization holder | BAUSCH HEALTH, CANADA INC. |
| Health Canada schedule | Prescription |
| ATC code | J04AC51 |
| ATC anatomical main group | J — Anti-infectives for systemic use |
| ATC therapeutic subgroup | J04AC |
| Current status | DORMANT |
| Status date | 09-Dec-2020 |
| Original market date | 1967-12-31 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
How is it administered?
Adults: 5-10 mg/kg (max 300 mg) daily. Children: 10-20 mg/kg (max 300-500 mg) daily. Preventive: 300 mg daily for adults. Usually administered orally.
Included because it drives pack selection and wastage. Consult the monograph.
Contraindications
Chronic or acute liver disease, history of isoniazid-associated hepatic injury, severe adverse reactions (hypersensitivity, drug fever, chills, arthritis).
Warnings and precautions
Risk of severe/fatal hepatitis; monitor for prodromal symptoms. Periodic liver function tests and ophthalmologic exams required. Risk of drug-resistant bacteria if used inappropriately.
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
2 · Same class — other molecules in ATC J04AC
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Isoniazid | DOM-ISONIAZID 300MG TABLETS · ISONIAZID SYRUP 50MG/5ML · ISONIAZID TAB 100MG · ISONIAZID TAB 300MG · +5 more | 18 | 3 | Yes |
| Isoniazid, Combinations | ISOTAMINE B 300 | 1 | 0 | Not in Canada |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC J04A
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| J04AB | Capreomycin · Cycloserine · Rifabutin · Rifampicin | 8 | 3 |
| J04AK | Ethambutol · Pyrazinamide | 8 | 3 |
| J04AA | Sodium Aminosalicylate | 1 | 0 |
| J04AM | Rifampicin, Pyrazinamide And Isoniazid | 1 | 0 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
How can I get it?
This DIN is dormant — it holds a Health Canada authorization but is not currently being marketed in Canada, so it cannot simply be ordered from Canadian stock. Where a patient need exists, supply may be possible through exceptional importation or the Special Access Programme, subject to Health Canada's requirements and the prescriber's application. Nexara can advise on the route and on marketed alternatives.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.