ADRENALIN TOPICAL SOLUTION 1 MG — DIN 00155365
EPINEPHRINE (EPINEPHRINE HYDROCHLORIDE) : 1 MG · SEARCHLIGHT PHARMA INC · SOLUTION · wholesale supply in Canada
Health Canada status: MARKETED

What is ADRENALIN TOPICAL SOLUTION?
ADRENALIN TOPICAL SOLUTION 1 MG contains EPINEPHRINE (EPINEPHRINE HYDROCHLORIDE) : 1 MG. It is listed in the Health Canada Drug Product Database under DIN 00155365, held by SEARCHLIGHT PHARMA INC, supplied as SOLUTION for TOPICAL administration. Health Canada currently lists it as marketed, status dated 06-Oct-2022. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is ADRENALIN TOPICAL SOLUTION used for?
Hemostatic agent in mucosal and sinus surgery, such as endonasal surgeries and endodontic mini-surgeries when reduction of local hemorrhage is indicated.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
How much does Epinephrine cost around the world?
Epinephrine is listed on 6 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.
What a market publishes matters more than the number it publishes. Bahrain publishes a retail (max); Greece publishes a producer price (ex-factory); Morocco publishes a PPV (public price). Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.
| Market | Price basis published there | Brands | Packs listed | Range |
|---|---|---|---|---|
| United States | acquisition | 3 | 13 | USD███.██ |
| Saudi Arabia | public | 7 | 7 | SAR███.██ |
| Morocco | PPV (public price) | 3 | 6 | MAD███.██ |
| Greece | producer price (ex-factory) | 4 | 4 | EUR███.██ |
| Bahrain | retail (max) | 1 | 1 | BHD███.██ |
| South Africa | single exit price | 1 | 1 | ZAR███.██ |
32 pack listings across 19 brand entries and 6 price bases, refreshed 10 Sep 2026. Ranges span every Epinephrine pack in that market, so a high figure is usually a larger pack rather than the same product.
Canada publishes no comparable public list price. For a delivered Canadian price on a licensed account, verify your licence — it takes about a minute.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 1 MG |
|---|---|
| Dosage form | SOLUTION |
| Route | TOPICAL |
| Pack configuration (monograph) | Vials of 30 mL with a removable tear-off metal ferrule and rubber stopper. |
| Storage | Protect from light and freezing. Store at room temperature between 15 °C and 30 °C. Do not remove from carton until ready to use. |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Epinephrine |
|---|---|
| ATC code | B02BC09 |
| AHFS class | 52:32.00 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 00155365 |
|---|---|
| DIN (unpadded, as printed on some documents) | 155365 |
| Brand name | ADRENALIN TOPICAL SOLUTION |
| Generic / active ingredient | EPINEPHRINE (EPINEPHRINE HYDROCHLORIDE) : 1 MG |
| Market authorization holder | SEARCHLIGHT PHARMA INC |
| Health Canada schedule | Prescription |
| ATC code | B02BC09 |
| ATC anatomical main group | B — Blood and blood-forming organs |
| ATC therapeutic subgroup | B02BC |
| Current status | MARKETED |
| Status date | 06-Oct-2022 |
| Original market date | 1951-12-31 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
How is it administered?
For topical use only. Apply 1 mg/mL solution locally with a sterile swab as required. Do not inject. Remove metal ferrule and rubber stopper to pour out solution.
Included because it drives pack selection and wastage. Consult the monograph.
Contraindications
Narrow angle glaucoma, shock during general anesthesia with halogenated hydrocarbons, organic brain damage, local anesthesia of fingers/toes, labour, cardiac dilatation, coronary insufficiency.
Warnings and precautions
DO NOT INJECT. Inadvertent injection can result in cardiac arrest and death. Use caution in elderly, cardiovascular disease, hypertension, diabetes, hyperthyroidism, or asthma. Contains sulfites.
Is Epinephrine in shortage in Canada?
A Canadian shortage report is on file for a product containing this molecule: Active — reported by PFIZER CANADA ULC, last seen 11 Sep 2026. A shortage on one presentation does not always affect every DIN of the molecule — the alternatives below list what else is marketed in Canada. Nexara can confirm current availability and identify substitutions or import options where permitted.
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
2 · Same class — other molecules in ATC B02BC
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Combinations | ARTISS · EVICEL · QUIXIL · TACHOSIL · +3 more | 12 | 5 | Yes |
| Epinephrine | ADRENALIN TOPICAL SOLUTION | 1 | 1 | Yes |
| Thrombin | THROMBINAR PWS 5000UNIT/VIAL · THROMBOGEN · THROMBOGEN SPRAY KIT · THROMBOSTAT 10000UNITS · +2 more | 9 | 0 | Not in Canada |
| Local Hemostatics | ULTRAPLAST ALGINATE STYPTIC GAUZE | 1 | 0 | Not in Canada |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC B02B
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| B02BD | Catridecacog · Coagulation Factor Ix · Coagulation Factor Ix, Ii, Vii And X In Comb · Coagulation Factor Viia · Coagulation Factor Viii · +8 more | 216 | 73 |
| B02BX | Avatrombopag · Concizumab · Eltrombopag · Emicizumab · Fostamatinib · +1 more | 23 | 15 |
| B02BA | Phytomenadione | 5 | 2 |
| B02BB | Fibrinogen, Human | 2 | 2 |
4 · Fixed-dose combinations with Canadian supply
| Product | Active ingredients | Holder | Status | DIN |
|---|---|---|---|---|
| ADYNOVATE | ANTIHEMOPHILIC FACTOR (RECOMBINANT), PEGYLATED : 1000 UNIT | TAKEDA CANADA INC | MARKETED | 02498588 |
| ALPROLIX | RECOMBINANT HUMAN COAGULATION FACTOR IX, FC FUSION PROTEIN : 500 UNIT | SANOFI-AVENTIS CANADA INC | MARKETED | 02422913 |
| ALTUVIIIO | *ANTIHEMOPHILIC FACTOR VIII (RECOMBINANT, BDD), FC-VWF-XTEN FUSION PROTEIN : 4000 UNIT | SANOFI-AVENTIS CANADA INC | MARKETED | 02448157 |
| ELOCTATE | ANTIHEMOPHILIC FACTOR (RECOMBINANT BDD), FC FUSION PROTEIN : 500 UNIT | SANOFI-AVENTIS CANADA INC | MARKETED | 02430304 |
| ESPEROCT | ANTIHEMOPHILIC FACTOR VIII (RECOMBINANT, B-DOMAIN TRUNCATED), PEGYLATED : 2000 UNIT | NOVO NORDISK CANADA INC | MARKETED | 02490099 |
| JIVI | ANTIHEMOPHILIC FACTOR (RECOMBINANT, B-DOMAIN DELETED, PEGYLATED) : 1000 UNIT | BAYER INC | MARKETED | 02481774 |
| REBINYN | COAGULATION FACTOR IX (RECOMBINANT), PEGYLATED : 3000 UNIT | NOVO NORDISK CANADA INC | MARKETED | 02532964 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
What is Epinephrine called in other languages?
Buyers, prescribers and procurement teams outside Canada often search for the ingredient in their own script. These are phonetic renderings of the ingredient name Epinephrine, published to help those searches reach this page.
| Language | Epinephrine |
|---|---|
| Arabic العربية | إبينفرين |
| Chinese (Simplified) 简体中文 | 肾上腺素 |
| Russian Русский | Эпинефрин |
| Spanish Español | Epinefrina |
| French Français | Épinéphrine |
| Portuguese Português | Epinefrina |
| German Deutsch | Epinephrin |
| Japanese 日本語 | エピネフリン |
These are transliterations of the ingredient name, generated automatically and published only where two independent checks agreed. They are not registered local trade names and carry no marketing authorisation in any market. Always confirm a product against its local registration before ordering.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.