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MEGACILLIN 500 SUS Strength — DIN 00009938

Active ingredient(s) See footnote 8 : Strength PENICILLIN G BENZATHINE : 500000 UNIT / 5 ML · MERCK FROSST CANADA & CIE, MERCK FROSST CANADA & CO. 16711 Trans Canada Highway Kirkland Quebec Canada H9H 3L1 · Suspension · wholesale supply in Canada

Health Canada status: CANCELLED POST MARKET

What is MEGACILLIN 500 SUS?

MEGACILLIN 500 SUS Strength contains Active ingredient(s) See footnote 8 : Strength PENICILLIN G BENZATHINE : 500000 UNIT / 5 ML. It is listed in the Health Canada Drug Product Database under DIN 00009938, held by MERCK FROSST CANADA & CIE, MERCK FROSST CANADA & CO. 16711 Trans Canada Highway Kirkland Quebec Canada H9H 3L1, supplied as Suspension for Oral administration. Health Canada currently lists it as cancelled post market, status dated 21-Apr-1998. This Drug Identification Number is no longer authorized for sale in Canada, so Nexara does not supply it. The record is kept here because buyers still meet the number on old formularies, purchase orders and tender documents; Nexara can help identify an authorized alternative.

How much does Benzathine Benzylpenicillin cost around the world?

Benzathine Benzylpenicillin is listed on 3 of the national price registers Nexara ingests. Each country publishes on a different basis, so those figures are not comparable with one another — or with a Canadian wholesale price.

What a market publishes matters more than the number it publishes. Australia publishes a ex-manufacturer; Iceland publishes a max wholesale; South Africa publishes a single exit price. Comparing an ex-factory ceiling against a pharmacy public price tells you nothing about either, and comparing either against a Canadian landed cost tells you less.

MarketPrice basis published thereBrandsPacks listedRange
Australiaex-manufacturer414AUD███.██
South Africasingle exit price810ZAR███.██
Icelandmax wholesale22ISK███.██

26 pack listings across 14 brand entries and 3 price bases, refreshed 08 Sep 2026. Ranges span every Benzathine Benzylpenicillin pack in that market, so a high figure is usually a larger pack rather than the same product.

Figures are held for the Nexara team. Cross-market prices are published on incompatible bases and are not an offer, a landed cost, or a guide to what any buyer can obtain. Nexara publishes which markets list the product and on what basis; the numbers stay internal.

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This table is a regulatory record of where the molecule is listed. The DIN on this page is no longer authorized for sale in Canada, so Nexara does not quote it — see the alternatives above.

Is there a generic Benzathine Benzylpenicillin in Canada, and who makes it?

Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.

3 holders have a Canadian DIN containing Benzathine Benzylpenicillin, across 3 DINs, of which 0 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.

Market authorization holderDINsMarketedBrand namesPosition
MERCK FROSST CANADA & CIE, MERCK FROSST CANADA & CO.10MEGACILLIN 250 PEDI SUSNo marketed DIN
MERCK FROSST CANADA & CIE, MERCK FROSST CANADA & CO. 16711 Trans Canada Highway Kirkland Quebec Canada H9H 3L110MEGACILLIN 500 SUSNo marketed DIN
WYETH-AYERST CANADA INC.10BICILLIN L-A INJECTION SUS 1200000IU/2MLNo marketed DIN

Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.

How is it supplied and stored?

Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.

Strength on the labelStrength
Dosage formSuspension
RouteOral

Pack detail is kept as a regulatory record. This DIN is no longer authorized for sale in Canada, so Nexara does not quote this pack.

Substance and classification

Active substanceBenzathine Benzylpenicillin
ATC codeJ01CE08
Biosimilar biologicNo

Health Canada record and identifiers

The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.

DIN (8-digit, as used in ordering)00009938
DIN (unpadded, as printed on some documents)9938
Brand nameMEGACILLIN 500 SUS
Generic / active ingredientActive ingredient(s) See footnote 8 : Strength PENICILLIN G BENZATHINE : 500000 UNIT / 5 ML
Market authorization holderMERCK FROSST CANADA & CIE, MERCK FROSST CANADA & CO. 16711 Trans Canada Highway Kirkland Quebec Canada H9H 3L1
Health Canada schedulePRESCRIPTION
ATC codeJ01CE08
ATC anatomical main groupJ — Anti-infectives for systemic use
ATC therapeutic subgroupJ01CE
Current statusCANCELLED POST MARKET
Status date21-Apr-1998
Original market date1961-12-31
Status sourceLive Health Canada DPD sync

Verify on the primary sources

Health Canada DPD record

What can be used instead?

Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.

1 · Same molecule, other Canadian presentations

0 of 3 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.

ProductStrengthFormHolderHealth Canada statusDIN
BICILLIN L-A INJECTION SUS 1200000IU/2ML1200000 UNIT / 2 MLSUSPENSIONWYETH-AYERST CANADA INC.CANCELLED POST MARKET02041596
MEGACILLIN 250 PEDI SUS250000 UNIT / 5 MLSUSPENSIONMERCK FROSST CANADA & CIE, MERCK FROSST CANADA & CO.CANCELLED POST MARKET00107441

2 · Same class — other molecules in ATC J01CE

MoleculeCanadian brandsDINsMarketedSourceable
BenzylpenicillinCRYSTAPEN · CRYSTAPEN 1 000 000 IU PWS · CRYSTAPEN 10000000 IU PWS · CRYSTAPEN 10M I.U. · +25 more363Yes
PhenoxymethylpenicillinAPO PEN VK · LEDERCILLIN VK - TAB 400000 UNIT · LEDERCILLIN VK - TAB 800000UNITS · LEDERCILLIN VK TAB 400000UNIT · +16 more211Yes
Benzathine PhenoxymethylpenicillinPEN VEE SUS 180MG · PEN-VEE SUSPENSION 180 MG · PEN-VEE SUSPENSION 180MG/5ML · PEN-VEE SUSPENSION 300 MG · +3 more70Not in Canada
Benzathine BenzylpenicillinBICILLIN L-A INJECTION SUS 1200000IU/2ML · MEGACILLIN 250 PEDI SUS · MEGACILLIN 500 SUS30Not in Canada
CombinationsBICILLIN A-P INJECTION PWS10Not in Canada
Procaine PenicillinAYERCILLIN SUSPENSION10Not in Canada

A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.

3 · Adjacent classes in ATC J01C

ATC subgroupMoleculesDINsMarketed
J01CAAmoxicillin · Ampicillin · Ampicillin, Combinations · Bacampicillin · Piperacillin · +3 more20147
J01CRAmoxicillin And Beta-Lactamase Inhibitor · Piperacillin And Beta-Lactamase Inhibitor · Ticarcillin And Beta-Lactamase Inhibitor11344
J01CFBeta-Lactamase Resistant Penicillins · Cloxacillin · Flucloxacillin429

Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.

What else is MEGACILLIN 500 SUS called?

The same molecule, Benzathine Benzylpenicillin, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:

NameScriptRegistered in
Bicillin L-ALatinAustralia
Benzetacil (Spain)LatinAustralia
Benzylpenicillin BenzathineLatinIceland
TardocillinLatinIceland
UltracillinLatinSouth Africa

Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.

Can this still be bought in Canada?

No. This Drug Identification Number is cancelled post market in Health Canada's Drug Product Database, so the product is no longer authorized for sale in Canada and Nexara does not supply it. This page is kept as a regulatory record.

If you are looking for a current equivalent, the alternatives above list every product sharing this therapeutic class, with the marketed ones first. Ask us to source an alternative

Ordering questions

Who can buy this from Nexara?

Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.

Is there a minimum order?

Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.

What is the lead time?

Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.

Why is there no price on this page?

Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.

Can Nexara supply this for a clinical trial?

Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.

Sources and disclaimer

Product data sourced from the Health Canada Drug Product Database. Health Canada status reconciled against the live DPD sync. Last reviewed 11 Sep 2026.

Nothing on this page is medical advice. Nexara Health is a licensed wholesale distributor and supplies licensed entities only; consumer orders are routed to a partner pharmacy. Alternatives tables describe supply, not clinical equivalence.

Health Canada Drug Product Database (DPD), DIN 00009938. Last reviewed 2026-09-11. Nexara Health is a licensed wholesaler and supplies licensed entities only; consumer orders are routed to a partner pharmacy.