APL INJ 1000 IU/ML 1000 UNIT — DIN 00002291
CHORIONIC GONADOTROPIN : 1000 UNIT · AYERST LABORATORIES · LIQUID · wholesale supply in Canada
Health Canada status: CANCELLED POST MARKET
What is APL INJ 1000 IU/ML?
APL INJ 1000 IU/ML 1000 UNIT contains CHORIONIC GONADOTROPIN : 1000 UNIT. It is listed in the Health Canada Drug Product Database under DIN 00002291, held by AYERST LABORATORIES, supplied as LIQUID for INTRAMUSCULAR administration. Health Canada currently lists it as cancelled post market, status dated 02-Aug-2000. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
Is there a generic Chorionic Gonadotrophin in Canada, and who makes it?
Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.
6 holders have a Canadian DIN containing Chorionic Gonadotrophin, across 6 DINs, of which 2 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.
| Market authorization holder | DINs | Marketed | Brand names | Position |
|---|---|---|---|---|
| FRESENIUS KABI CANADA LTD | 1 | 1 | CHORIONIC GONADOTROPIN FOR INJECTION, USP | Sourceable in Canada |
| ORGANON CANADA INC. | 1 | 1 | PREGNYL | Sourceable in Canada |
| AYERST LABORATORIES | 1 | 0 | APL INJ 1000 IU/ML | No marketed DIN |
| EMD SERONO, A DIVISION OF EMD INC., CANADA | 1 | 0 | PROFASI HP 10000 | No marketed DIN |
| PHARMASCIENCE INC | 1 | 0 | PROFASI HP INJ 10000UNIT/VIAL USP | No marketed DIN |
| WYETH-AYERST CANADA INC. | 1 | 0 | A.P.L. - PWS-LIQ | No marketed DIN |
Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 1000 UNIT |
|---|---|
| Dosage form | LIQUID |
| Route | INTRAMUSCULAR |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Chorionic Gonadotrophin |
|---|---|
| ATC code | G03GA01 |
| AHFS class | 68:18.00 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 00002291 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2291 |
| Brand name | APL INJ 1000 IU/ML |
| Generic / active ingredient | CHORIONIC GONADOTROPIN : 1000 UNIT |
| Market authorization holder | AYERST LABORATORIES |
| Health Canada schedule | Prescription |
| ATC code | G03GA01 |
| ATC anatomical main group | G — Genito-urinary system and sex hormones |
| ATC therapeutic subgroup | G03GA |
| Current status | CANCELLED POST MARKET |
| Status date | 02-Aug-2000 |
| Original market date | 1951-12-31 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
1 · Same molecule, other Canadian presentations
2 of 6 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.
| Product | Strength | Form | Holder | Health Canada status | DIN |
|---|---|---|---|---|---|
| CHORIONIC GONADOTROPIN FOR INJECTION, USP | 10000 UNIT | POWDER FOR SOLUTION | FRESENIUS KABI CANADA LTD | MARKETED | 02247459 |
| PREGNYL | 10000 UNIT | POWDER FOR SOLUTION ; KIT | ORGANON CANADA INC. | MARKETED | 02182904 |
| A.P.L. - PWS-LIQ | 10000 UNIT | LIQUID ; POWDER FOR SOLUTION | WYETH-AYERST CANADA INC. | CANCELLED POST MARKET | 02168936 |
| PROFASI HP 10000 | 10 ML | KIT ; POWDER FOR SOLUTION ; LIQUID | EMD SERONO, A DIVISION OF EMD INC., CANADA | CANCELLED POST MARKET | 01925679 |
| PROFASI HP INJ 10000UNIT/VIAL USP | 10000 UNIT | POWDER FOR SOLUTION | PHARMASCIENCE INC | CANCELLED POST MARKET | 00598534 |
2 · Same class — other molecules in ATC G03GA
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Follitropin Alfa | GONAL-F · GONAL-F PEN | 10 | 3 | Yes |
| Follitropin Delta | REKOVELLE | 6 | 3 | Yes |
| Combinations | PERGOVERIS | 4 | 3 | Yes |
| Chorionic Gonadotrophin | A.P.L. - PWS-LIQ · APL INJ 1000 IU/ML · CHORIONIC GONADOTROPIN FOR INJECTION, USP · PREGNYL · PROFASI HP 10000 · PROFASI HP INJ 10000UNIT/VIAL USP | 6 | 2 | Yes |
| Choriogonadotropin Alfa | OVIDREL | 2 | 2 | Yes |
| Follitropin Beta | PUREGON · PUREGON (600 IU) · PUREGON 100 I.U. · PUREGON 50 I.U. | 6 | 1 | Yes |
| Human Menopausal Gonadotrophin | HUMEGON INJ 75 I.U. · MENOPUR · PERGONAL 75 I.U. · REPRONEX | 4 | 1 | Yes |
| Urofollitropin | BRAVELLE · FERTINORM HP 150 - PWS DILUENT IM SC · FERTINORM HP 75 - PWS DILUENT IM SC · METRODIN 75 I.U. | 4 | 0 | Not in Canada |
| Lutropin Alfa | LUVERIS | 1 | 0 | Not in Canada |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC G03G
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| G03GB | Clomifene | 4 | 0 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
Can this still be bought in Canada?
No. This Drug Identification Number is cancelled post market in Health Canada's Drug Product Database, so the product is no longer authorized for sale in Canada and Nexara does not supply it. This page is kept as a regulatory record.
If you are looking for a current equivalent, the alternatives above list every product sharing this therapeutic class, with the marketed ones first. Ask us to source an alternative
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.