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XYLOCAINE 2% W EPINEPHRINE 1:100000 0.01 MG — DIN 00001821

EPINEPHRINE (EPINEPHRINE BITARTRATE) : 0.01 MG LIDOCAINE HYDROCHLORIDE : 20 MG · ASTRAZENECA CANADA INC · LIQUID · wholesale supply in Canada

Health Canada status: CANCELLED POST MARKET

What is XYLOCAINE 2% W EPINEPHRINE 1:100000?

XYLOCAINE 2% W EPINEPHRINE 1:100000 0.01 MG contains EPINEPHRINE (EPINEPHRINE BITARTRATE) : 0.01 MG LIDOCAINE HYDROCHLORIDE : 20 MG. It is listed in the Health Canada Drug Product Database under DIN 00001821, held by ASTRAZENECA CANADA INC, supplied as LIQUID for BLOCK/INFILTRATION administration. Health Canada currently lists it as cancelled post market, status dated 12-Sep-2012. This Drug Identification Number is no longer authorized for sale in Canada, so Nexara does not supply it. The record is kept here because buyers still meet the number on old formularies, purchase orders and tender documents; Nexara can help identify an authorized alternative.

What is XYLOCAINE 2% W EPINEPHRINE 1:100000 used for?

XYLOCAINE Parenteral Solutions (lidocaine hydrochloride) are indicated for production of local or regional anesthesia by infiltration techniques including percutaneous injection, peripheral nerve block techniques such as brachial plexus and intercostal blocks, and central neural techniques including epidural and caudal blocks, when the accepted procedures for these techniques, as described in standard textbooks, are observed.

Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.

Is there a generic Lidocaine, Combinations in Canada, and who makes it?

Every market authorization holder with a Canadian DIN for this molecule, and how many of their listings Health Canada currently shows as marketed.

21 holders have a Canadian DIN containing Lidocaine, Combinations, across 72 DINs, of which 16 are currently marketed. Marketed count is the number that matters: an approval that is not marketed cannot be bought.

Market authorization holderDINsMarketedBrand namesPosition
SEPTODONT65LIDOCAINE 2% AND EPINEPHRINE 1:100,000, LIDOCAINE 2% AND EPINEPHRINE 1:50,000, LIGNOSPAN FORTE, LIGNOSPAN SPECIALE INJ, LIGNOSPAN STANDARD, +1 moreSourceable in Canada
ASPEN PHARMACARE CANADA INC.44XYLOCAINE 1% W EPINEPHRINE 1:100000, XYLOCAINE 1% W EPINEPHRINE 1:200000, XYLOCAINE 2% W EPINEPHRINE 1:200000, XYLOCAINE 2% WITH EPINEPHRINE 1:200000Sourceable in Canada
DENTSPLY CANADA LIMITED42DENTSPLY 2% LIDOCAINE WITH EPINEPHRINE 1:100,000, DENTSPLY 2% LIDOCAINE WITH EPINEPHRINE 1:50,000, XYLOCAINE DENTAL LIDOCAINE HCL 2% AND EPINEPHRINE 1:100,000, XYLOCAINE DENTAL LIDOCAINE HYDROCHLORIDE 2% AND EPINEPHRINE 1:50,000Sourceable in Canada
NOVOCOL PHARMACEUTICAL OF CANADA INC31OCTOCAINE 100 NEEDLEJECT INJ, OCTOCAINE HCL 2% EPINEPHRINE 1:100000, OCTOCAINE HCL 2% EPINEPHRINE 1:50000Sourceable in Canada
PFIZER CANADA ULC31LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE INJECTION USPSourceable in Canada
HIKMA CANADA LIMITED11LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE INJECTION USPSourceable in Canada
PENDOPHARM DIVISION OF PHARMASCIENCE INC11INSTILLAGELSourceable in Canada
SCIENCES DE LA PEAU CRESCITA INC. / CRESCITA SKIN SCIENCES INC.11PLIAGLISSourceable in Canada
BAXTER CORPORATION140CONTINUOUS EPIDURAL ANESTHESIA TRAY, EPIDURAL ANESTHESIA TRAY, PARACENTESIS TRAY W BOASBERG CATHETER SET, SINGLE-SHOT EPIDURAL ANESTHESIA TRAY, SPINAL ANAESTHESIA TRAY, +1 moreNo marketed DIN
ARROW INTERNATIONAL INC.110ARROW CENTRAL VENOUS CATHETERIZATION KIT, ARROW MULTI-LUMEN CENTRAL VENOUS CATHETER KIT, ARROW PNEUMOTHORAX KIT, ARROW TWO-LUMEN CENTRAL VENOUS CATHETAR KIT, ARROW TWO-LUMEN JUGULAR CATHETERIZATION KIT, +6 moreNo marketed DIN
ASTRAZENECA CANADA INC50XYLOCAINE 0.5% W EPINEPHRINE 1:100000, XYLOCAINE 0.5% W EPINEPHRINE 1:200000, XYLOCAINE 1.5% W EPINEPHRINE 1:200000, XYLOCAINE 1.5% W EPINEPHRINE 1:200000 TEST DOSE, XYLOCAINE 2% W EPINEPHRINE 1:100000No marketed DIN
ALLEGIANCE HEALTHCARE CORPORATION30GENETIC AMNIOCENTESIS TRAY KIT, JAMSHIDI BONE MARROW BIOPSY TRAY, JAMSHIDI MENGHINI SOFT TISSUE BIOPSY TRAYNo marketed DIN

Health Canada’s Drug Product Database does not flag which listing is the originator and which are subsequent-entry products, so Nexara does not label them here. Interchangeability is determined provincially, not federally — confirm for your province before a formulary switch. Nexara can confirm which of these is actually obtainable, and on what lead time, per order.

How is it supplied and stored?

Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.

Strength on the label0.01 MG
Dosage formLIQUID
RouteBLOCK/INFILTRATION
Pack configuration (monograph)null
Storagenull

Pack detail is kept as a regulatory record. This DIN is no longer authorized for sale in Canada, so Nexara does not quote this pack.

Substance and classification

Active substanceLidocaine, Combinations
ATC codeN01BB52
AHFS class72:00.00
Biosimilar biologicNo

Health Canada record and identifiers

The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.

DIN (8-digit, as used in ordering)00001821
DIN (unpadded, as printed on some documents)1821
Brand nameXYLOCAINE 2% W EPINEPHRINE 1:100000
Generic / active ingredientEPINEPHRINE (EPINEPHRINE BITARTRATE) : 0.01 MG LIDOCAINE HYDROCHLORIDE : 20 MG
Market authorization holderASTRAZENECA CANADA INC
Health Canada scheduleEthical
ATC codeN01BB52
ATC anatomical main groupN — Nervous system
ATC therapeutic subgroupN01BB
Current statusCANCELLED POST MARKET
Status date12-Sep-2012
Original market date1955-12-31 00:00:00
Status sourceLive Health Canada DPD sync

Verify on the primary sources

Health Canada DPD record Approved product monograph (PDF)

What can be used instead?

Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.

1 · Same molecule, other Canadian presentations

16 of 72 Canadian DINs for this molecule are currently marketed. Marketed products are listed first.

ProductStrengthFormHolderHealth Canada statusDIN
INSTILLAGEL0.05 %GELPENDOPHARM DIVISION OF PHARMASCIENCE INCMARKETED02294990
LIDOCAINE 2% AND EPINEPHRINE 1:100,00020 MGSOLUTIONSEPTODONTMARKETED02473518
LIDOCAINE 2% AND EPINEPHRINE 1:50,00020 MGSOLUTIONSEPTODONTMARKETED02473526
LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE INJECTION USP20 MGSOLUTIONPFIZER CANADA ULCMARKETED01901915
LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE INJECTION USP0.01 MGSOLUTIONHIKMA CANADA LIMITEDMARKETED02436221
LIGNOSPAN FORTE36 MCG / 1.8 MLSOLUTIONSEPTODONTMARKETED00375799
LIGNOSPAN STANDARD36 MG / 1.8 MLSOLUTIONSEPTODONTMARKETED00375780
OCTOCAINE HCL 2% EPINEPHRINE 1:1000000.01 MGSOLUTIONNOVOCOL PHARMACEUTICAL OF CANADA INCMARKETED00151866
PLIAGLIS7 %CREAMSCIENCES DE LA PEAU CRESCITA INC. / CRESCITA SKIN SCIENCES INC.MARKETED02398028
XYLOCAINE 1% W EPINEPHRINE 1:10000010 MGSOLUTIONASPEN PHARMACARE CANADA INC.MARKETED00001791

2 · Same class — other molecules in ATC N01BB

MoleculeCanadian brandsDINsMarketedSourceable
LidocaineAMNIOCENTESIS TRAY 1% · ANTECUBITAL CENT VENOUS CATHETERIZATION KIT · ARTHROGRAM TRAY 1% · ATELOCOLLAGEN IMPLANT · +39 more7226Yes
Lidocaine, Combinations2% LIDOCAINE AND EPINEPHRINE 1:100,000 INJECTION USP · 5% XYLOCAINE MPF WITH GLUCOSE 7.5% INJECTION · ARROW CENTRAL VENOUS CATHETERIZATION KIT · ARROW MULTI-LUMEN CENTRAL VENOUS CATHETER KIT · +55 more7216Yes
Articaine, Combinations4% ASTRACAINE DENTAL WITH EPINEPHRINE 1:200,000 (0.005MG/ML) · 4% ASTRACAINE DENTAL WITH EPINEPHRINE FORTE 1:100,000 (0.01MG/ML) · ARTICAINE HYDROCHLORIDE AND EPINEPHRINE BITARTRATE INJECTION · ORABLOC 1:100,000 · +10 more1812Yes
BupivacaineBUPIVACAINE HEAVY INJECTION BP · BUPIVACAINE HYDROCHLORIDE IN DEXTROSE INJECTION USP · BUPIVACAINE HYDROCHLORIDE INJECTION USP · BUPIVACAINE HYDROCHLORIDE INJECTION USP .25% · +12 more4210Yes
Mepivacaine3% POLOCAINE DENTAL · CARBOCAINE 1% · CARBOCAINE 2% · CARBOCAINE 3% · +7 more157Yes
RopivacaineNAROPIN · NAROPIN INJ 7.5MG/ML · ROPIVACAINE HYDROCHLORIDE INJECTION · ROPIVACAINE HYDROCHLORIDE INJECTION USP · +2 more136Yes
Bupivacaine, CombinationsBUPIVACAINE HCL 0.5% AND EPINEPHRINE 1:200,000 INJECTION · MARCAINE · MARCAINE 0.5% AND EPINEPHRINE 1:200,000 LIQ · MARCAINE E · +5 more125Yes
Prilocaine, Combinations4% CITANEST FORTE DENTAL WITH EPINEPHRINE 1:200,000 · DENTSPLY 4% PRILOCAINE AND EPINEPHRINE INJECTION 1:200,000 · EMLA CREAM · EMLA PATCH · +1 more54Yes
CombinationsCETACAINE LIQUID · ORAQIX22Yes
Prilocaine4% CITANEST PLAIN DENTAL · DENTSPLY 4% PRILOCAINE HYDROCHLORIDE DENTAL INJECTION21Yes

A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.

3 · Adjacent classes in ATC N01B

ATC subgroupMoleculesDINsMarketed
N01BABenzocaine · Chloroprocaine · Combinations,Of Anesthetics · Procaine · Tetracaine131
N01BXPhenol10

Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.

What else is XYLOCAINE 2% W EPINEPHRINE 1:100000 called?

The same molecule, Lidocaine, Combinations, is registered under other names elsewhere. Buyers and prescribers searching from outside Canada — or working from a foreign prescription or tender document — often know it by one of these:

NameScriptRegistered in
Xylocain Dental adrenalinLatinIceland
LidentLatinIceland
Lidocaina/Epinefrina NormonLatinIceland
Lidokain-tetrakain - forskriftarlyfLatinIceland
Xylocain adrenalinLatinIceland

Names are taken from national medicine registers and published price lists. A product registered abroad is not authorized for sale in Canada unless it holds its own DIN; import is possible only through the routes Health Canada permits.

What is Lidocaine called in other languages?

Buyers, prescribers and procurement teams outside Canada often search for the ingredient in their own script. These are phonetic renderings of the ingredient name Lidocaine, published to help those searches reach this page.

LanguageLidocaine
Chinese (Simplified) 简体中文利多卡因
Russian Русскийлидокаин
Spanish Españollidocaína
French Françaislidocaïne
Portuguese Portuguêslidocaína
German DeutschLidocain
Hindi हिन्दीलिडोकेन
Persian فارسیلیدوکائین
Turkish Türkçelidokain
Japanese 日本語リドカイン
Korean 한국어리도카인
Italian Italianolidocaina

These are transliterations of the ingredient name, generated automatically and published only where two independent checks agreed. They are not registered local trade names and carry no marketing authorisation in any market. Always confirm a product against its local registration before ordering.

Can this still be bought in Canada?

No. This Drug Identification Number is cancelled post market in Health Canada's Drug Product Database, so the product is no longer authorized for sale in Canada and Nexara does not supply it. This page is kept as a regulatory record.

If you are looking for a current equivalent, the alternatives above list every product sharing this therapeutic class, with the marketed ones first. Ask us to source an alternative

Ordering questions

Who can buy this from Nexara?

Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.

Is there a minimum order?

Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.

What is the lead time?

Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.

Why is there no price on this page?

Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.

Can Nexara supply this for a clinical trial?

Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.

Sources and disclaimer

Product data sourced from the Health Canada Drug Product Database and the approved product monograph (PDF). Health Canada status reconciled against the live DPD sync. Last reviewed 11 Sep 2026.

Nothing on this page is medical advice. Nexara Health is a licensed wholesale distributor and supplies licensed entities only; consumer orders are routed to a partner pharmacy. Alternatives tables describe supply, not clinical equivalence.

Health Canada Drug Product Database (DPD), DIN 00001821. Last reviewed 2026-09-11. Nexara Health is a licensed wholesaler and supplies licensed entities only; consumer orders are routed to a partner pharmacy.