Nexara Health — Health Canada Drug Establishment Licence #3-002896

RATIO-TOPISALIC 0.5 MG

Last verified 2026-09-08 · Source: Health Canada Drug Product Database (DPD), DIN 02245688

RATIO-TOPISALIC 0.5 MG

BETAMETHASONE (BETAMETHASONE DIPROPIONATE) : 0.5 MG SALICYLIC ACID : 20 MG · DIN 02245688 · TEVA CANADA LIMITED

Health Canada status: CANCELLED POST MARKET

What is RATIO-TOPISALIC?

RATIO-TOPISALIC 0.5 MG contains BETAMETHASONE (BETAMETHASONE DIPROPIONATE) : 0.5 MG SALICYLIC ACID : 20 MG. It is listed in the Health Canada Drug Product Database under DIN 02245688, held by TEVA CANADA LIMITED, supplied as LOTION for TOPICAL administration. Health Canada currently lists it as cancelled post market, status dated 27-Mar-2026. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.

What is RATIO-TOPISALIC used for?

Anti-inflammatory, antipruritic and keratolytic activity for topical management of subacute and chronic hyperkeratotic and dry dermatoses responsive to corticosteroid therapy.

Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.

Product details and regulatory record

DIN02245688
Brand nameRATIO-TOPISALIC
Generic / active ingredientBETAMETHASONE (BETAMETHASONE DIPROPIONATE) : 0.5 MG SALICYLIC ACID : 20 MG
ManufacturerTEVA CANADA LIMITED
Strength0.5 MG
Dosage formLOTION
Route of administrationTOPICAL
SchedulePrescription
ATC codeD07XC01 BETAMETHASONE
AHFS class84:06.00 ; 84:28.00
BiosimilarNo
Health Canada statusCANCELLED POST MARKET
Status date27-Mar-2026
Original market date2002-05-03 00:00:00

How is it administered?

Apply a thin film to cover affected areas of the scalp completely. Usual frequency is twice daily. Do not use under occlusive dressings.

Included because it drives pack selection and wastage. Consult the monograph.

How is it stored and handled?

Store between 15°C and 30°C.

How is it supplied?

Plastic squeeze bottles of 30 mL and 60 mL.

Contraindications

Hypersensitivity to any ingredient; viral diseases (vaccinia, varicella, herpes simplex); fungal infections; tuberculosis of the skin.

Warnings and precautions

Avoid contact with eyes and mucous membranes. Systemic absorption increases if used on extensive areas or with long-term use. May cause HPA axis suppression or visual disturbances.

What can be used instead?

Other Canadian products sharing ATC code D07XC01 BETAMETHASONE. 2 of 4 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.

ProductStrengthFormManufacturerHealth Canada statusDIN
DIPROSALIC0.5 MGOINTMENTORGANON CANADA INC.MARKETEDDIN 00578436
TEVA-BETAMETHASONE/ CALCIPOTRIOL0.5 MGOINTMENTTEVA CANADA LIMITEDMARKETEDDIN 02427419
DIPROSALIC0.5 MGLOTIONORGANON CANADA INC.CANCELLED POST MARKETDIN 00578428

Who else supplies BETAMETHASONE worldwide?

Nexara tracks national medicine registries and published price lists across multiple markets. BETAMETHASONE appears in 2437 registered pack listings across 12 markets, published on 10 different national price bases. Where a Canadian route is closed, that is where an alternative route of supply starts — subject to the import rules in both countries.

Registered listings are not stock. Ask us to confirm what can actually be sourced for your order.

How can I get it?

Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.

Request a quote for RATIO-TOPISALIC

Ordering questions

Who can buy this from Nexara?

Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.

Is there a minimum order?

Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.

What is the lead time?

Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.

Can Nexara supply this for a clinical trial?

Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.

Related pages

Sourcing this product