ISOPTO CARPINE 1 %
PILOCARPINE HYDROCHLORIDE : 1 % · DIN 00000841 · NOVARTIS PHARMACEUTICALS CANADA INC
Health Canada status: CANCELLED POST MARKET
What is ISOPTO CARPINE?
ISOPTO CARPINE 1 % contains PILOCARPINE HYDROCHLORIDE : 1 %. It is listed in the Health Canada Drug Product Database under DIN 00000841, held by NOVARTIS PHARMACEUTICALS CANADA INC, supplied as LIQUID for OPHTHALMIC administration. Health Canada currently lists it as cancelled post market, status dated 24-May-2017. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is ISOPTO CARPINE used for?
Indicated for the reduction of intraocular pressure.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
Product details and regulatory record
| DIN | 00000841 |
|---|---|
| Brand name | ISOPTO CARPINE |
| Generic / active ingredient | PILOCARPINE HYDROCHLORIDE : 1 % |
| Manufacturer | NOVARTIS PHARMACEUTICALS CANADA INC |
| Strength | 1 % |
| Dosage form | LIQUID |
| Route of administration | OPHTHALMIC |
| Schedule | Prescription |
| ATC code | S01EB01 PILOCARPINE |
| AHFS class | 52:40.20 |
| Biosimilar | No |
| Health Canada status | CANCELLED POST MARKET |
| Status date | 24-May-2017 |
| Original market date | 1959-12-31 00:00:00 |
How is it administered?
Instill 2 drops topically in the affected eye(s) 3 or 4 times daily. Nasolacrimal occlusion or gently closing the eyelid after administration is recommended.
Included because it drives pack selection and wastage. Consult the monograph.
How is it stored and handled?
Store at room temperature. Avoid excessive heat. Keep bottle tightly closed when not in use.
How is it supplied?
15 mL DROP-TAINER dispensers.
Contraindications
Hypersensitivity to drug or ingredients; conditions where pupillary constriction is undesirable (e.g., acute iritis or anterior uveitis).
Warnings and precautions
Caution in patients with cardiac failure, asthma, peptic ulcer, Parkinson's. Risk of retinal detachment. Miosis may cause blurred vision/difficulty in dark adaptation; caution driving at night.
What can be used instead?
Other Canadian products sharing ATC code S01EB01 PILOCARPINE. 2 of 42 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.
| Product | Strength | Form | Manufacturer | Health Canada status | DIN |
|---|---|---|---|---|---|
| ISOPTO CARPINE | 2 % | LIQUID | NOVARTIS PHARMACEUTICALS CANADA INC | MARKETED | DIN 00000868 |
| MINIMS PILOCARPINE NITRATE | 2 % | DROPS | BAUSCH & LOMB INC | MARKETED | DIN 02148463 |
| ISOPTO CARPINE | 4 % | LIQUID | NOVARTIS PHARMACEUTICALS CANADA INC | CANCELLED POST MARKET | DIN 00000884 |
| ISOPTO CARPINE 0.5% | 0.5 % | LIQUID | ALCON CANADA INC | CANCELLED POST MARKET | DIN 00000833 |
| ISOPTO CARPINE LIQ 6% | 60 G | LIQUID | ALCON CANADA INC | CANCELLED POST MARKET | DIN 00000892 |
| MINIMS PILOCARPINE NITRATE 4% | 4 % | DROPS | CHAUVIN PHARMACEUTICALS LIMITED | CANCELLED POST MARKET | DIN 02148471 |
| MIOCARPINE OPH SOLN 1% | 1 % | DROPS | IOLAB PHARMACEUTICALS | CANCELLED POST MARKET | DIN 00759945 |
| MIOCARPINE OPH SOLN 2% | 2 % | DROPS | IOLAB PHARMACEUTICALS | CANCELLED POST MARKET | DIN 00759961 |
| MIOCARPINE OPH SOLN 4% | 4 % | DROPS | IOLAB PHARMACEUTICALS | CANCELLED POST MARKET | DIN 00760099 |
| MIOCARPINE OPH SOLN 6% | 6 % | DROPS | IOLAB PHARMACEUTICALS | CANCELLED POST MARKET | DIN 00759953 |
Who else supplies PILOCARPINE worldwide?
Nexara tracks national medicine registries and published price lists across multiple markets. PILOCARPINE appears in 36 registered pack listings across 8 markets, published on 7 different national price bases. Where a Canadian route is closed, that is where an alternative route of supply starts — subject to the import rules in both countries.
Registered listings are not stock. Ask us to confirm what can actually be sourced for your order.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.