APO-VORTIOXETINE 10 MG
VORTIOXETINE (VORTIOXETINE HYDROBROMIDE) : 10 MG · DIN 02552752 · APOTEX INC
Health Canada status: MARKETED
What is APO-VORTIOXETINE?
APO-VORTIOXETINE 10 MG contains VORTIOXETINE (VORTIOXETINE HYDROBROMIDE) : 10 MG. It is listed in the Health Canada Drug Product Database under DIN 02552752, held by APOTEX INC, supplied as TABLET for ORAL administration. Health Canada currently lists it as marketed, status dated 15-Apr-2025. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is APO-VORTIOXETINE used for?
Treatment of major depressive disorder (MDD) in adults.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
Product details and regulatory record
| DIN | 02552752 |
|---|---|
| Brand name | APO-VORTIOXETINE |
| Generic / active ingredient | VORTIOXETINE (VORTIOXETINE HYDROBROMIDE) : 10 MG |
| Manufacturer | APOTEX INC |
| Strength | 10 MG |
| Dosage form | TABLET |
| Route of administration | ORAL |
| Schedule | Prescription |
| ATC code | N06AX26 VORTIOXETINE |
| Biosimilar | No |
| Health Canada status | MARKETED |
| Status date | 15-Apr-2025 |
How is it administered?
Recommended starting dose 10 mg once daily. May increase to 20 mg or decrease to 5 mg based on response. Administer with or without food. Gradual reduction recommended for discontinuation.
Included because it drives pack selection and wastage. Consult the monograph.
How is it stored and handled?
Not explicitly stated in provided text (standard section 11 was in TOC but text cut off).
How is it supplied?
Bottles of 100 tablets.
Contraindications
Hypersensitivity to vortioxetine or any ingredient; Concomitant use of MAOIs (including linezolid, methylene blue) or within 14 days of MAOI discontinuation.
Warnings and precautions
Increased risk of self-harm and suicidal behavior; Serotonin Toxicity/Neuroleptic Malignant Syndrome; Abnormal bleeding; Bone fracture risk; Seizures; Angle-closure glaucoma.
What can be used instead?
Other Canadian products sharing ATC code N06AX26 VORTIOXETINE. 6 of 8 DINs in this group are currently marketed — marketed products are listed first, because that is what can actually be bought. These tables describe supply, not clinical equivalence: substitution rests with the prescriber or pharmacist, and interchangeability is determined provincially.
| Product | Strength | Form | Manufacturer | Health Canada status | DIN |
|---|---|---|---|---|---|
| APO-VORTIOXETINE | 20 MG | TABLET | APOTEX INC | MARKETED | DIN 02552779 |
| APO-VORTIOXETINE | 5 MG | TABLET | APOTEX INC | MARKETED | DIN 02552744 |
| TRINTELLIX | 10 MG | TABLET | LUNDBECK CANADA INC | MARKETED | DIN 02432927 |
| TRINTELLIX | 20 MG | TABLET | LUNDBECK CANADA INC | MARKETED | DIN 02432943 |
| TRINTELLIX | 5 MG | TABLET | LUNDBECK CANADA INC | MARKETED | DIN 02432919 |
| APO-VORTIOXETINE | 15 MG | TABLET | APOTEX INC | APPROVED | DIN 02552760 |
| TRINTELLIX | 15 MG | TABLET | LUNDBECK CANADA INC | APPROVED | DIN 02432935 |
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.