EXTRANEAL 4.48 G — DIN 02240806
SODIUM LACTATE : 4.48 G SODIUM CHLORIDE : 5.35 G ICODEXTRIN : 75 G MAGNESIUM CHLORIDE : 51 MG CALCIUM CHLORIDE : 257 MG · VANTIVE ULC · SOLUTION · wholesale supply in Canada
Health Canada status: MARKETED
What is EXTRANEAL?
EXTRANEAL 4.48 G contains SODIUM LACTATE : 4.48 G SODIUM CHLORIDE : 5.35 G ICODEXTRIN : 75 G MAGNESIUM CHLORIDE : 51 MG CALCIUM CHLORIDE : 257 MG. It is listed in the Health Canada Drug Product Database under DIN 02240806, held by VANTIVE ULC, supplied as SOLUTION for HAEMODIALYSIS (INTRAPERITONEAL) administration. Health Canada currently lists it as marketed, status dated 12-Apr-2024. Nexara Health is a licensed Canadian wholesale distributor (DEL 3-002896-A) and can source this product for hospitals, pharmacies and clinics. Availability and lead time are confirmed per order.
What is EXTRANEAL used for?
EXTRANEAL (icodextrin, sodium chloride, sodium lactate, calcium chloride, magnesium chloride) is indicated for use as an osmotic agent for long dwell, up to 12 hours, in continuous ambulatory peritoneal dialysis (CAPD) or automated peritoneal dialysis (APD), where it can be used for 14 and up to 16 hours.
Authorized indication as written in the Health Canada product monograph. For healthcare professionals and licensed purchasers; this is not medical advice.
How is it supplied and stored?
Pack configuration, storage class and the handling constraints that drive cold-chain planning. One DIN can cover more than one pack size, and the pack — not the DIN — is what gets priced, shipped and invoiced.
| Strength on the label | 4.48 G |
|---|---|
| Dosage form | SOLUTION |
| Route | HAEMODIALYSIS (INTRAPERITONEAL) |
| Pack configuration (monograph) | 2000 mL or 2500 mL bag |
| Storage | room temperature (15-25 °C). Do not store below 4 °C. |
Before an order line is unambiguous Nexara needs the strength, the pack size and the presentation.
Substance and classification
| Active substance | Isotonic Solutions |
|---|---|
| ATC code | B05DA |
| AHFS class | 24:24.00 |
| Biosimilar biologic | No |
Health Canada record and identifiers
The regulatory facts straight from the Drug Product Database, plus every identifier form Nexara accepts on a purchase order. A DIN written without its leading zeros is the commonest reason an order line fails to match.
| DIN (8-digit, as used in ordering) | 02240806 |
|---|---|
| DIN (unpadded, as printed on some documents) | 2240806 |
| Brand name | EXTRANEAL |
| Generic / active ingredient | SODIUM LACTATE : 4.48 G SODIUM CHLORIDE : 5.35 G ICODEXTRIN : 75 G MAGNESIUM CHLORIDE : 51 MG CALCIUM CHLORIDE : 257 MG |
| Market authorization holder | VANTIVE ULC |
| Health Canada schedule | Ethical |
| ATC code | B05DA |
| ATC anatomical main group | B — Blood and blood-forming organs |
| ATC therapeutic subgroup | B05DA |
| Current status | MARKETED |
| Status date | 12-Apr-2024 |
| Original market date | 2000-04-19 00:00:00 |
| Status source | Live Health Canada DPD sync |
Verify on the primary sources
How is it administered?
Intraperitoneal single daily exchange for long dwell: up to 12 hours (CAPD) or 14-16 hours (APD). Instill 2000-2500 mL over 10-20 minutes. Aseptic technique required.
Included because it drives pack selection and wastage. Consult the monograph.
Contraindications
Acute renal failure; allergy to starch-based polymers or icodextrin; maltose/isomaltose intolerance; glycogen storage disease; severe lactic acidosis; uncorrectable mechanical defects; adhesions.
Warnings and precautions
Use only glucose-specific monitors (avoid GDH-PQQ/GDO/GDH-FAD) to prevent fatal hypoglycemia/mismanagement. Risk of Encapsulating Peritoneal Sclerosis (EPS) and hypersensitivity reactions.
What can be used instead?
Alternatives on every axis a buyer actually considers — the same molecule in another presentation, the same class, an adjacent class, or a fixed-dose combination. Every row is led by the marketed DIN count, because that is what can be bought this week.
2 · Same class — other molecules in ATC B05DA
| Molecule | Canadian brands | DINs | Marketed | Sourceable |
|---|---|---|---|---|
| Isotonic Solutions | EXTRANEAL | 1 | 1 | Yes |
A molecule with zero marketed DINs cannot be sourced domestically, however many approvals it holds — if one of these sits on a formulary or in an older protocol, that is the line to check.
3 · Adjacent classes in ATC B05D
| ATC subgroup | Molecules | DINs | Marketed |
|---|---|---|---|
| B05DB | Hypertonic Solutions | 21 | 3 |
Not clinical advice. These tables describe what can be supplied in Canada, not what should be prescribed. Substitution within or across classes is a prescriber and pharmacist decision, and interchangeability is determined provincially.
How can I get it?
Nexara Health supplies this product to licensed Canadian buyers — pharmacies, hospitals, clinics, licensed distributors, and clinical trial sponsors or their CROs. We confirm stock, pack size, expiry and pricing at the time of quotation. If the product is on backorder or in shortage, we identify equivalent alternatives and import options where permitted.
Ordering questions
Who can buy this from Nexara?
Licensed entities only. Nexara holds Health Canada establishment licence DEL 3-002896-A and ships only to a licensed address. Patients and unlicensed buyers are routed to a partner pharmacy.
Is there a minimum order?
Yes, set per product line and per pack multiple rather than on the order total, so you are never asked to buy a part-pack. The minimum for this line is confirmed with your quote.
What is the lead time?
Confirmed per order at quotation, and it depends on current stock position and whether the product is in shortage.
Why is there no price on this page?
Nexara quotes a delivered Canadian price per order, against a verified licence. Foreign list prices are published on incompatible bases and are not a guide to what any buyer can obtain here, so this page shows which markets list the molecule and on what basis, and nothing more.
Can Nexara supply this for a clinical trial?
Yes — comparator and background-therapy supply, including sourcing from other markets where a Canadian pack will not satisfy the protocol. Clinical trial supply.